Can Listening to Music Improve Attention and Language After Post-Stroke Aphasia?

Sponsor
Purdue University
Study ID
NCT07198048
Status
Not Yet Recruiting

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Conditions

  • Aphasia
  • Music Intervention
  • Stroke
  • Stroke Hemorrhagic
  • Stroke Ischemic
  • Stroke and Aphasia

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Music-Based Therapy for Post Stroke Aphasia — BEHAVIORAL
    Participants will be instructed to maintain their usual activities each day, except we will ask them to select a time of day, a comfortable and distraction free environment, and an apparatus for regular music listening (earbuds, headphones, speakers). Participants will listen mindfully to randomized selections from the playlist that meets their needs that day (i.e., energizing or relaxing). Participants will listen to their music selections on shuffle for 30 minutes per day for 8 weeks using the strategies provided by the music therapist. The target listening duration is 30 minutes as it is a common target for time spent on task before taking a break. Participants will complete their daily journal entry immediately after music listening. The music therapist will make a weekly telephone call to each participant in the experimental arm. The telephone call will last \~30 minutes. During this telephone call, the music therapist will update the music playlists and help submit their logs.
  • Audiobook Intervention for Post Stroke Aphasia — BEHAVIORAL
    Participants will be instructed to maintain their usual activities each day, except we will ask them to select a time of day, a comfortable and distraction free environment, and an apparatus for regular music listening (earbuds, headphones, speakers). Participants will listen mindfully to an audiobook selected with a speech-language pathologist (SLP). Participants will listen to their audiobook for 30 minutes per day for 8 weeks using the strategies provided by the SLP. The target listening duration is 30 minutes as it is a common target for time spent on task before taking a break. Participants will complete their daily journal entry immediately after audiobook listening. The SLP will make a weekly telephone call to each participant in the experimental arm. The telephone call will last \~30 minutes. During this telephone call, the SLP will update the audiobook library and help submit their logs.

Study Details

The goal of this clinical trial is to learn if a music-based intervention can acutely improve three types of attention (alerting, orientating, executive control) in people with aphasia following a stroke. The main questions it aims to answer are: 1. Is a music based intervention effective at improving attention with someone who has aphasia? 2. Does music-induced changes in attention improve language abilities and quality of life with someone who has aphasia? Researchers will compare a group that listening to music, to listing to an audiobook group, to a group that serves as a control to see if there are changes in attention over time. Participants will: 1. Listen to music or an audiobook for 30 minutes a day for 8 weeks 2. Complete a daily journal about each day's listening experience 3. Complete three testing sessions where attention, language, and quality of life are assessed.

Key Dates

First listed
Sep 30, 2025
Start date
Oct 31, 2025
Status verified
Sep 2025
Primary completion
Jan 31, 2028
Completion
Jul 1, 2028

Study Design

Enrollment
45 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Music Based Intervention
    Participants in this arm will participate in the music intervention. For this intervention, participants will work with a music therapist and attend to music for 30 minutes each day over the course of 10 weeks.
  • Active Comparator: Audiobook listeners
    Participants in this arm will participate in the audiobook intervention. For this intervention, participants will work with a speech-language pathologist and attend to audiobooks for 30 minutes each day over the course of 10 weeks.
  • No Intervention: No Contact Control
    The no-contact control arm is designed to demonstrate that any behavioral changes observed in the experimental (MBI) arm are due to the intervention itself, rather than spontaneous recovery processes. While PWA did not achieve full recovery through spontaneous processes, they may still experience improvements over time that occur independently of therapeutic interventions. The use of a no-contact control arm allows us to determine whether any changes observed in the experimental arm exceed those that might naturally occur without participation in the intervention.

Primary Outcome Measure

Change in attention from T1 to T2 and T3 [ Time Frame: From T1 to T2 (11 weeks for the experimental and active control arms, 9 weeks for the no-contact arm) and to T3 (8 weeks after T2) ]

Central Contacts

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