Stroke Clinical Trials

Recruiting stroke studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat stroke. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting stroke studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting stroke trials

Within

REstoring Flow by REvascularization With Submaximal Angioplasty in Hemodynamic IntraCranial Atherosclerotic Stenosis

for Intracranial Atherosclerotic Disease

1 site in Cleveland

Sponsor: Case Western Reserve University

Sex: All·Age: 30 - 90

Code: NCT03729817

The Feasibility and Acceptability of a Gait Training Program Based on Telerehabilitation After Stroke

for Stroke

Sponsor: University of Exeter

Sex: All·Age: 18+

Code: NCT07623018

The Disrupted Bodily Self of Patients

for Stroke

Sponsor: University of Geneva, Switzerland

Sex: All·Age: 20 - 85

Code: NCT04957576

Optimal Dosing of High-Intensity Locomotor Training for Step Attainment and Locomotor Outcomes in Stroke Patients Undergoing Acute Inpatient Rehabilitation

for Stroke

1 site in New York

Sponsor: NYU Langone Health

Sex: All·Age: 18 - 95

Code: NCT06637839

Effects of Task-Oriented Sit-to-Stand Training Using Immersive VR and PNF on Quality of Life in Chronic Stroke: Trial Protocol

for Stroke

Sponsor: Universidad Nacional Autonoma de Mexico

Sex: All·Age: 35 - 71

Code: NCT07713446

Clinical Efficacy of Exoskeleton Assistance for Individuals Post-Stroke

for Stroke

1 site in Atlanta

Sponsor: Georgia Institute of Technology

Sex: All·Age: 18 - 85

Code: NCT06064604

A Study on the Application of Positive Psychological Counseling Based on "Dou Bao" Software in Patients With Post-stroke Depression

for Stroke

Sponsor: The Fourth Affiliated Hospital of Zhejiang University School of Medicine

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07336888

Relaxin Therapy for Atrial Fibrillation

for Atrial Fibrillation (AF)

Sponsor: Deeptankar DeMazumder

Sex: All·Age: 18+

Code: NCT07359872·Phase 1, Phase 2

Improving Awareness for Spatial Neglect With tDCS

for Stroke

Sponsor: University of Geneva, Switzerland

Sex: All·Age: 20 - 85

Code: NCT04845529

Computerized Decision Support to Prevent Stroke in Atrial Fibrillation

for Atrial Fibrillation

2 sites incl. Edgewood

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT06355986

Assessment of Safety and Effectiveness of Spatial StimelMD (SSMD) in Subjects With Upper Limb Neuromotor Impairments

for Stroke

Sponsor: Motion Informatics LTD

Sex: All·Age: 18 - 80

Code: NCT07396922

tACS and Upper Limb Rehabilitation in Chronic Stroke

for Stroke

Sponsor: National University Hospital, Singapore

Sex: All·Age: 21 - 80

Code: NCT07778342

Bedside Cranial Ultrasound for Risk-Stratified Imaging in Pediatric Acute Brain Injury

for Acute Brain Injury

1 site in Richmond

Sponsor: Virginia Commonwealth University

Sex: All·Age: 2 - 17

Code: NCT07772323

Visual Restoration Using Focused Ultrasound Stimulation and Immersive Virtual Reality After Stroke

for Stroke

1 site in Durham

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06875206

Application of Digital Twins' Technology in Patients Who Had a Stroke, With Moyamoya Disease and With Cerebral Amyloid Angiopathy (CAA) During the Secondary Prevention Phase: A Proof of Concept Using a Randomized Control Trial (Clinical Study 6, STRATIF-AI Project)

for Stroke

Sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta

Sex: All·Age: 18+

Code: NCT06714097

Apply to this trial

Smartphone Application to PREDICT Real-Time Cardiovascular Risk for Heart Attack and Stroke

for Myocardial Infarction (MI)

1 site in Stanford

Sponsor: Stanford University

Sex: All·Age: 40 - 79·Accepts healthy volunteers

Code: NCT07735338

Creatine Supplementation in Pediatric Brain Injury

for Brain Injury

Sponsor: Spaulding Rehabilitation Hospital

Sex: All·Age: 8 - 25

Code: NCT07756060

Zastaprazan for the prEvention of Upper GI Bleeding in Ischemic Stroke

for Ischemic Stroke

Sponsor: Asan Medical Center

Sex: All·Age: 19+

Code: NCT07730840·Phase 3

AI-Assisted Workflow for Occult Atrial Fibrillation Detection After Ischemic Stroke: A Prospective Randomized Trial

for Atrial Fibrillation

Sponsor: National Taiwan University Hospital

Sex: All·Age: 18+

Code: NCT07540065

PIRe 2.0: A Stepped-Care Model for Involving Relatives Across Sectors

for Brain Injuries, Acute

Sponsor: Rigshospitalet, Denmark

Sex: All·Age: 18+

Code: NCT07590726

This Study Evaluates the Use of a Data-driven Lower Limb Exoskeleton Controller for Stroke Rehabilitation.

for Stroke

1 site in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT07616167

A Phase 3 Trial of Lesion Network Mapping-Guided cTBS for Motor Recovery After Acute Ischemic Stroke

for Ischemic Stroke

Sponsor: Beijing Tiantan Hospital

Sex: All·Age: 18 - 80

Code: NCT07645586·Phase 3

Pilot RCT of Computer-based Eye Movement Training

for Stroke

Sponsor: Glasgow Caledonian University

Sex: All·Age: 18+

Code: NCT07752563

APEX-STROKE CALM-ICH Domain

for Stroke

Sponsor: Fudan University

Sex: All·Age: 18+

Code: NCT07752719·Phase 3

The BASIC-S Feasibility Study for Vascular Risk Reduction

for Hypertension (HTN)

Sponsor: Andrew Appleton

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07755631

Lifescapes System in Post-stroke Hand Recovery

for Stroke

Sponsor: National University Hospital, Singapore

Sex: All·Age: 21 - 80

Code: NCT07784920

Colchicine for the Reduction of Dependency and Vascular Events After an Acute Intracerebral Hemorrhage

for Colchicine

Sponsor: Population Health Research Institute

Sex: All·Age: 18+

Code: NCT06587737·Phase 3

Combination Antithrombotic Treatment for Prevention of Recurrent Ischemic Stroke in IntraCranial Atherosclerotic diseaSe (CATIS- ICAS)

for Ischemic Stroke

Sponsor: Population Health Research Institute

Sex: All·Age: 40+

Code: NCT07468448·Phase 3

Glucagon-like Peptide-1 Receptor Agonists for Endovascular Stroke Thrombectomy

for Ischemic Stroke

Sponsor: Population Health Research Institute

Sex: All·Age: 18+

Code: NCT07511543·Phase 3

Smartwatch-Guided Secondary Prevention After Stroke

for Stroke

Sponsor: University Hospital, Brest

Sex: All·Age: 40 - 75

Code: NCT07640360

Experimental PBT Study in Fall-prone Subjects

for Stroke

Sponsor: University Rehabilitation Institute, Republic of Slovenia

Sex: All·Age: 18 - 75

Code: NCT07654335

Neuroplastic Changes Due to an Exercise Intervention That Aid in Lower Limb Recovery After Subcortical Stroke

for Subcortical Lesions

2 sites in Atlanta

Sponsor: Emory University

Sex: All·Age: 18 - 80

Code: NCT07663292

Apply to this trial

Impact of Presenting Symptoms on Treatment Time and Outcomes in Acute Ischemic Stroke

for Acute Ischemic Stroke

Sponsor: Assiut University

Sex: All·Age: 18+

Code: NCT07750847

Impact of Stroke Unit Care on Acute Stroke Outcomes

for Acute Stroke

Sponsor: Assiut University

Sex: All·Age: 18+

Code: NCT07750860

Comparative Study of Embolic Agents in Patients With Subdural Hemorrhage Undergoing Middle Meningeal Artery (MMA) Embolization

for Chronic Subdural Hematoma

1 site in Sioux Falls

Sponsor: Sanford Health

Sex: All·Age: 18+

Code: NCT07757113

Huayu Jiedu Formula (FTFY-919) Granules Versus Traditional Decoction for Acute Hypertensive Intracerebral Hemorrhage

for Intracerebral Hemorrhage

Sponsor: Guangzhou University of Traditional Chinese Medicine

Sex: All·Age: 40+

Code: NCT07801599·Phase 3

Self-Managed Exercise in Chronic Stroke

for Stroke

1 site in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 89

Code: NCT07799987

Endovascular Treatment for Acute Large Vessel Occlusion With Ultra-Large Ischemic Core

for AIS

Sponsor: First Affiliated Hospital of Harbin Medical University

Sex: All·Age: 18+

Code: NCT07791810

Immuno-inflammatory Profile and Response to Ischemic Stroke Reperfusion Therapies (IMMUNOSTROKE)

for Stroke

Sponsor: Fondation Ophtalmologique Adolphe de Rothschild

Sex: All·Age: 18 - 90

Code: NCT04701619

Prevention of Infection of the Respiratory Tract Through Application of Non-Invasive Methods of Secretion Suctioning

for Intubation Complication

Sponsor: Hospital San Carlos, Madrid

Sex: All·Age: 18+

Code: NCT06113939·Phase 4

Tenecteplase (TNK) in the Treatment of Intracerebral Hemorrhage (ICH)

for Intracerebral Hemorrhage

Sponsor: Gaurav Gupta, MD

Sex: All·Age: 18 - 80

Code: NCT06696131·Phase 1

Augmenting Cerebral Blood Flow in Acute Ischemic Stroke

for Stroke

Sponsor: University of Alberta

Sex: All·Age: 18+

Code: NCT06911385·Phase 1, Phase 2

PLasmatic Extracellular Vesicles AS Biomarkers of nEural Tissue Damage

for Multiple Sclerosis

Sponsor: Roberto Furlan

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07769294

Effects of High-Frequency rTMS on Cortical Motor Mapping in Stroke Patients With Severe Upper Limb Impairment (MAP2024SJD)

for Stroke

Sponsor: Ancor Rebassa Cabrera

Sex: All·Age: 18+

Code: NCT07787793

Apply to this trial

Telerehabilitation for Post-Stroke Hand Function

for Stroke

1 site in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 40 - 75

Code: NCT07792655

Apply to this trial

Transcranial Direct Current Stimulation for Neurogenic Overactive Bladder Symptoms Among People With Stroke

for Stroke

Sponsor: The Hong Kong Polytechnic University

Sex: All·Age: 18 - 80

Code: NCT07768137

Non-Invasive Deep Brain Stimulation for Upper Limb Recovery After Stroke (NIMBUS)

for Stroke

Sponsor: Friedhelm Hummel

Sex: All·Age: 18+

Code: NCT07792811·Phase 2, Phase 3

Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke

for Stroke

1 site in Bethesda

Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All·Age: 18 - 99

Code: NCT06615973

Apply to this trial

BurtVision™ for Arm Rehabilitation in Chronic Stroke Survivors:

for Stroke

Sponsor: Spaulding Rehabilitation Hospital

Sex: All·Age: 18 - 80

Code: NCT04940403

Stroke Cerebral Reorganization Pathways (SPECTRE)

for Brain Diseases

Sponsor: Rennes University Hospital

Sex: All·Age: 18 - 75

Code: NCT06784518

Proprioceptive Error Correction for Post-Stroke Upper Limb Rehabilitation

for Ischemic Stroke

Sponsor: Sungkyunkwan University

Sex: All·Age: 19+

Code: NCT07156955

Apply to this trial

Effect of Mental Arithmetic Priming on Gait and Balance in Stroke

for Stroke

Sponsor: Lebanese University

Sex: All·Age: 60 - 80

Code: NCT07327814

Individual vs Co-Treatment in Acute Stroke Rehabilitation and Evaluation

for Stroke

1 site in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT07411534

Enhancing Attention and Processing Speed Through Home-based Music Rehabilitation Program After Stroke in Malaysia

for Stroke

Sponsor: University of Malaya

Sex: All·Age: Up to 75

Code: NCT07522463

Potential for Recovery of Voluntary Finger Extension After Stroke

for Stroke

Sponsor: University College, London

Sex: All·Age: 18+

Code: NCT07592247

Studying Fatigue and Movement After Stroke

for Stroke

Sponsor: Vrije Universiteit Brussel

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07594938

Brain-controlled Spinal Cord Stimulation in Participants With Chronic Stroke for Lower and Upper Limb Rehabilitation

for Stroke

Sponsor: Ecole Polytechnique Fédérale de Lausanne

Sex: All·Age: 18 - 70

Code: NCT07610850

Apply to this trial

Investigating Central Contributions to Fatigue Using Non-invasive Brain Stimulation

for Stroke

Sponsor: Vrije Universiteit Brussel

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07613970·Phase 1, Phase 2

A Study of Probiotics in Patients With Acute Ischemic Stroke

for Ischemic Stroke

Sponsor: Capital Medical University

Sex: All·Age: 60+

Code: NCT07651332·Phase 2

Medico-Economic Evaluation of MRI Versus CT as Diagnostic Imaging Strategies in Patients With Suspected Ischemic Stroke: the MAGRITTE Study.

for Stroke

Sponsor: Fondation Ophtalmologique Adolphe de Rothschild

Sex: All·Age: 18+

Code: NCT07719374

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Stroke clinical trials — common questions

Are stroke clinical trials free to join?

Yes. Participating in a stroke clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a stroke clinical trial?

Each stroke study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a stroke trial near me?

Use the location controls above. We'll show recruiting stroke trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many stroke trials are recruiting right now?

We're currently tracking roughly 315 recruiting stroke trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Stroke trials by city

Chicago, IL Boston, MA Birmingham, AL Milwaukee, WI San Francisco, CA Cleveland, OH Los Angeles, CA Indianapolis, IN Jacksonville, FL Sacramento, CA Ann Arbor, MI Cincinnati, OH

Related specialties

Neurology Brain disorders