Cardiovascular Protection After Preeclampsia With Enalapril

Sponsor
Women and Infants Hospital of Rhode Island
Study ID
NCT07222852
Phase
PHASE3
Status
Not Yet Recruiting

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Conditions

  • Gestational Hypertension
  • Gestational Hypertension After Childbirth
  • Hypertension
  • Hypertensive Disorder of Pregnancy
  • Preeclampsia

Eligibility Criteria

Sex
FEMALE
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Enalapril — DRUG
    First-line anti-hypertensive treatment with enalapril
  • Standard treatment — OTHER
    First-line anti-hypertensive treatment per standard of care

Study Details

The purpose of this study is to learn if postpartum women are willing to be randomized to different blood pressure medicines after delivery and how that affects blood pressure in women with hypertensive disorders of pregnancy.

Key Dates

First listed
Oct 30, 2025
Start date
Nov 15, 2025
Status verified
Oct 2025
Primary completion
Oct 15, 2027
Completion
Oct 15, 2027

Study Design

Enrollment
60 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Enalapril
    First-line anti-hypertensive treatment with enalapril
  • Active Comparator: Standard treatment
    First-line anti-hypertensive treatment with standard of care treatment

Primary Outcome Measure

Feasibility of enrollment [ Time Frame: 4 months ]

Central Contacts

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