Hypertension (high blood pressure) Clinical Trials

Recruiting hypertension (high blood pressure) studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat hypertension (high blood pressure). Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting hypertension (high blood pressure) studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting hypertension (high blood pressure) trials

Within

Mobile Health Management of Hypertension

for Hypertension

1 site in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT05856955

Know Your Pressures NYC

for Glaucoma

1 site in New York

Sponsor: Columbia University

Sex: All·Age: 40+·Accepts healthy volunteers

Code: NCT05992415

Monitoring Blood Pressure at Home and Pharmacy Telehealth

for Hypertension

1 site in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT07623291

Optimizing Care For Management Of Hard To Control Hypertension In Low-Income Patients Across Family Health Centers In New York City

for Hypertension

1 site in New York

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT07703423

Community Hypertension Control Using the Health Belief Model and PRECEDE-PROCEED

for Hypertension

Sponsor: Bangladesh Medical University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07426978

PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study

for Heart Failure

1 site in Milwaukee

Sponsor: Medical College of Wisconsin

Sex: All·Age: 18+

Code: NCT05377320

Real-World Validation for Less-Disturbing Ambulatory Blood Pressure Monitoring (ABPM) in Malaysia Using Huawei Wearables

for Hypertension

Sponsor: Sunway University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07790978

A Study to Investigate Efficacy and Safety of a TCA108 in Participants ≥18 Years With Uncontrolled Hypertension

for Hypertension

Sponsor: EMS

Sex: All·Age: 18+

Code: NCT07030101·Phase 3

The Effects of Bifidobacterium-based Probiotics in Reducing Blood Pressure in Middle-aged Chinese With Hypertension

for Hypertension

Sponsor: The University of Hong Kong

Sex: All·Age: 40 - 65

Code: NCT07206303·Phase 1

A Clinical Study Comparing Ankle Swelling Caused by Two Different Blood Pressure Medications, Levamlodipine and Amlodipine, in Post-menopausal Women With Mild High Blood Pressure.

for Hypertension

Sponsor: Zentiva, k.s.

Sex: Female·Age: 50 - 79

Code: NCT07618806·Phase 3

Value of Potassium Magnesium Citrate in Preventing and Treating Hypertension in African Americans

for Hypertension

1 site in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT05145309·Phase 2

Renal Artery Denervation Assessment Without Antihypertensive Medication Regimen (RADAR)

for Hypertension

1 site in Knoxville

Sponsor: Ablative Solutions, Inc.

Sex: All·Age: 18 - 80

Code: NCT07083765·Phase 3

Consciousness Studies and Cardiovascular Health

for Blood Pressure

1 site in Miami

Sponsor: University of Miami

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07620639

A Phase 1 Clinical Trial to Evaluate the Safety and the Pharmacokinetic Drug-Drug Interaction Between HUC2A-752-A and HUC2A-752-B in Healthy Adults

for Hypertension

Sponsor: Huons Co., Ltd.

Sex: All·Age: 19 - 64·Accepts healthy volunteers

Code: NCT07784621·Phase 1

Emergency Department-Initiated Team-Based Care for Severe Hypertension

for Severe Hypertension

4 sites incl. Dearborn

Sponsor: Henry Ford Health System

Sex: All·Age: 18 - 85

Code: NCT07777237

A Study to Evaluate the Effect of Two Fixed-Dose Leucine, Sildenafil and Metformin Combinations on Blood Pressure in Individuals With Hypertension

for Hypertension

Sponsor: NuSirt Biopharma

Sex: All·Age: 18 - 75

Code: NCT07647003·Phase 2

Using Healthcare Financing and Digital Technology to Improve Hypertension Prevention and Control in Tanzania

for Hypertension

Sponsor: Dr. Karen Yeates

Sex: All·Age: 21 - 70

Code: NCT06379750

Guided Physical Activity Counseling for Hypertension in Primary Care

for Physical Activity

Sponsor: University of California, San Diego

Sex: All·Age: 18 - 80

Code: NCT07342543

Enhancing Mental and Physical Health of Women Veterans 3.0

for Cardiovascular Diseases

1 site in West Los Angeles

Sponsor: VA Office of Research and Development

Sex: All·Age: All ages

Code: NCT07356479

Evaluating the Effects of a Mindfulness Intervention on Health Outcomes in Individuals With Hypertension

for Hypertension

1 site in Columbus

Sponsor: Ohio State University

Sex: All·Age: 18+

Code: NCT07679984

INTEGRATE-RX: Integrating Clinical Pharmacists in HIV Care to Mitigate Last-Mile Challenges and Reduce Cardiovascular Disease Burden

for HIV

Sponsor: Temple University

Sex: All·Age: 18 - 75

Code: NCT07711366

Anticipated Stigma, Illness Identity, and Quality of Life in Male Hypogonadism

for Hypogonadism, Male

Sponsor: Hacettepe University

Sex: Male·Age: 18+

Code: NCT07752511

Real-World Validation of Huawei Wearable Technologies for Hypertension Risk Screening in Malaysia

for Hypertension

Sponsor: Sunway University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07785895

Tailoring TM-HTN Intervention for Black Patients

for Hypertension

1 site in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06593119

Impact of Transcutaneous Spinal Stimulation on Blood Pressure and Orthostasis in Spinal Cord Injury

for Spinal Cord Injuries

1 site in West Orange

Sponsor: Kessler Foundation

Sex: All·Age: 18 - 75

Code: NCT07674511

A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event

for Atherosclerosis

31 sites incl. Huntsville

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07783802·Phase 2

Regular Sauna Use to Lower Blood Pressure in Primary Aldosteronism

for Primary Aldosteronism

Sponsor: University of Calgary

Sex: All·Age: 18 - 65

Code: NCT07796048

Neurovascular Effects of Empagliflozin

for Blood Pressure

1 site in Iowa City

Sponsor: Kanokwan Bunsawat

Sex: All·Age: 45 - 75·Accepts healthy volunteers

Code: NCT07799441·Phase 4

Huayu Jiedu Formula (FTFY-919) Granules Versus Traditional Decoction for Acute Hypertensive Intracerebral Hemorrhage

for Intracerebral Hemorrhage

Sponsor: Guangzhou University of Traditional Chinese Medicine

Sex: All·Age: 40+

Code: NCT07801599·Phase 3

A Real-world Study of the Effectiveness of Angiotensin Receptor-Neprilysin Inhibitor Therapy in Hypertensive Patients in the United Arab Emirates

for Hypertension

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 99

Code: NCT07465666

Addressing Barriers to Anti-hypertensive Medication Adherence Among PLWH Who Have Achieved Viral Suppression

for Hypertension

1 site in Durham

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT05459077

Duke Cardiometabolic Prevention Clinic's Impact on High-risk Cardiovascular Patients With Uncontrolled Risk Factors

for ASCVD

1 site in Durham

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT07117695

Effectiveness of NeoMayor in Improving Cardiovascular Health in Chilean Older Adults

for Cardiovascular Health Status

Sponsor: University of Chile

Sex: All·Age: 55 - 75

Code: NCT07633392

SPIRO-First: A Pragmatic Primary Care-Embedded Pilot Trial of Renin-Guided First-Line Antihypertensive Therapy

for Hypertension

Sponsor: Ottawa Hospital Research Institute

Sex: All·Age: 18+

Code: NCT07687160·Phase 4

Micronutrient Enhancement for Development and Health in Adolescents - The MEDHA Study

for Neurodevelopment Outcome

Sponsor: Johns Hopkins Bloomberg School of Public Health

Sex: Female·Age: 10 - 18·Accepts healthy volunteers

Code: NCT07695883·Phase 3

AI-Guided Predictions of Blood Pressure Dysregulation Using Perfusion Index as a Novel Biomarker in Persons With Spinal Cord Injury

for Spinal Cord Injuries (SCI)

1 site in The Bronx

Sponsor: James J. Peters Veterans Affairs Medical Center

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07699094

Apply to this trial

Osilodrostat in Patients With Hypertension Caused by Hypercortisolaemia Due to Cushing's Syndrome

for Hypertension

Sponsor: RECORDATI GROUP

Sex: All·Age: 18+

Code: NCT07247162·Phase 4

Evaluation of a Novel Indoor Air Pollution Intervention Among Older Adults

for Cardiovascular Diseases

1 site in Missoula

Sponsor: University of Montana

Sex: All·Age: 55 - 79

Code: NCT07539987

Evaluating the Implementation Via Audit and Feedback

for Hypertension

Sponsor: Southern Medical University, China

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT07542587

MTM2MTG Pilot Ancillary Study

for Diet, Healthy

1 site in New York

Sponsor: Columbia University

Sex: All·Age: 20+

Code: NCT07620808

CEEEC-II: A 12-Week Physical and Cognitive Enrichment Extension Study in Older Stroke Survivors With Multimorbidity

for Stroke

Sponsor: Duke Kunshan University

Sex: All·Age: 60+

Code: NCT07778771

Potatoes, Type 2 Diabetes, and Cardiometabolic Health

for T2D

1 site in Blacksburg

Sponsor: Virginia Polytechnic Institute and State University

Sex: All·Age: 50 - 70·Accepts healthy volunteers

Code: NCT07229482

Apply to this trial

Comparison of Office and Cuffless Ambulatory Blood Pressure-Guided Management in Patients With Hypertension

for Hypertension

Sponsor: Seoul National University Hospital

Sex: All·Age: 30 - 79

Code: NCT07770477

Clinical Study to Evaluate the Pharmacokinetics and Safety of CKD-339 in Healthy Volunteers

for Hypertension

Sponsor: Chong Kun Dang Pharmaceutical

Sex: All·Age: 19 - 55·Accepts healthy volunteers

Code: NCT07748702·Phase 1

REFOCUS-HTN US-WEST: A Data Infrastructure to Characterize Individuals With Hypertension

for Hypertension

1 site in Oakland

Sponsor: Kaiser Permanente

Sex: All·Age: 18+

Code: NCT07780500

Apply to this trial

Decode the Environment Variation of Targeted Aldosterone Inducer and siLencer

for Hypertension

Sponsor: DejthidaNathaphong

Sex: All·Age: 18 - 100

Code: NCT07748975

The Impact of Low Sodium Salt Substitute Use on Serum Potassium Levels Among Patients With Hypertension

for Hypertension

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT07460882

Apply to this trial

A Trial Evaluating Safety, Tolerability and Efficacy of CTX340 in Participants With Hypertension

for Hypertension

1 site in Port Orange

Sponsor: CRISPR Therapeutics AG

Sex: All·Age: 18 - 75

Code: NCT07758634·Phase 1, Phase 2

Apply to this trial

Fixed-Dose Combinations Pragmatic Randomized Implementation Trial for Blood Pressure Control

for Hypertension

1 site in Milwaukee

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 80

Code: NCT07228065

Effects of Laser Acupuncture Treatment in Hypertension Haemodialysis Patients

for Hypertension

Sponsor: Sinai University

Sex: All·Age: 18 - 60

Code: NCT07170397

Virtual Lifestyle Medicine Group Visits for High Blood Pressure

for Hypertension

1 site in Houston

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 18+

Code: NCT07698509

Early Time-Restricted Eating for Cardiovascular Health

for Hypertension

1 site in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 60+

Code: NCT07634926

Faisalabad Initiative of Research and Management of NCDs

for Diabete Mellitus

Sponsor: Getz Pharma

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07676214

Blood Pressure Measured on the Arm With Different Layers of Clothing Versus on the Bare Arm in Patients at Grenoble Alpes University Hospital

for Blood Pressure

Sponsor: University Hospital, Grenoble

Sex: All·Age: 18+

Code: NCT07687771

A Blood Pressure-Lowering Diet for Preventing and Managing Hypertension

for Hypertension

Sponsor: Peking University

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT07735091

Nurse-Led Motivational Interviewing for Blood Pressure Control

for Hypertension

Sponsor: Kutahya Health Sciences University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07747025

Apply to this trial

Common Carotid Artery-Renal Artery-Femoral Artery Survey for Hypertension

for Hypertension

Sponsor: DejthidaNathaphong

Sex: All·Age: 18+

Code: NCT07760623

Implementation of a Beauty Salon-Based Strategy for Blood Pressure Management Among Women

for Hypertension

1 site in Baltimore

Sponsor: Johns Hopkins University

Sex: Female·Age: 18 - 79·Accepts healthy volunteers

Code: NCT07042386

Apply to this trial

Synthetic THC And Blood Pressure

for Blood Pressure

1 site in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 21 - 40

Code: NCT07231965·Phase 2, Phase 3

A Randomized Feasibility Trial Comparing Drospirenone and Norethindrone for Postpartum Hypertension Management in Preeclampsia

for Hypertension

1 site in Portland

Sponsor: Oregon Health and Science University

Sex: Female·Age: 18+

Code: NCT07293728·Phase 4

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Hypertension (high blood pressure) clinical trials — common questions

Are hypertension (high blood pressure) clinical trials free to join?

Yes. Participating in a hypertension (high blood pressure) clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a hypertension (high blood pressure) clinical trial?

Each hypertension (high blood pressure) study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a hypertension (high blood pressure) trial near me?

Use the location controls above. We'll show recruiting hypertension (high blood pressure) trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many hypertension (high blood pressure) trials are recruiting right now?

We're currently tracking roughly 245 recruiting hypertension (high blood pressure) trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Hypertension (high blood pressure) trials by city

Birmingham, AL Chicago, IL Boston, MA Miami, FL Cleveland, OH San Francisco, CA Aurora, CO Bloomington, IN Palo Alto, CA Ann Arbor, MI Boulder, CO Columbus, OH

Related specialties

Cardiology Heart disease