Hypertension (high blood pressure) Clinical Trials

Recruiting hypertension (high blood pressure) studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat hypertension (high blood pressure). Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting hypertension (high blood pressure) studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting hypertension (high blood pressure) trials

Within

Mobile Health Management of Hypertension

for Hypertension

1 site in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT05856955

Monitoring Blood Pressure at Home and Pharmacy Telehealth

for Hypertension

1 site in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT07623291

Optimizing Care For Management Of Hard To Control Hypertension In Low-Income Patients Across Family Health Centers In New York City

for Hypertension

1 site in New York

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT07703423

Community Hypertension Control Using the Health Belief Model and PRECEDE-PROCEED

for Hypertension

Sponsor: Bangladesh Medical University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07426978

PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study

for Heart Failure

1 site in Milwaukee

Sponsor: Medical College of Wisconsin

Sex: All·Age: 18+

Code: NCT05377320

A Study to Investigate Efficacy and Safety of a TCA108 in Participants ≥18 Years With Uncontrolled Hypertension

for Hypertension

Sponsor: EMS

Sex: All·Age: 18+

Code: NCT07030101·Phase 3

A Clinical Study Comparing Ankle Swelling Caused by Two Different Blood Pressure Medications, Levamlodipine and Amlodipine, in Post-menopausal Women With Mild High Blood Pressure.

for Hypertension

Sponsor: Zentiva, k.s.

Sex: Female·Age: 50 - 79

Code: NCT07618806·Phase 3

Value of Potassium Magnesium Citrate in Preventing and Treating Hypertension in African Americans

for Hypertension

1 site in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT05145309·Phase 2

Consciousness Studies and Cardiovascular Health

for Blood Pressure

1 site in Miami

Sponsor: University of Miami

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07620639

A Study to Evaluate the Effect of Two Fixed-Dose Leucine, Sildenafil and Metformin Combinations on Blood Pressure in Individuals With Hypertension

for Hypertension

Sponsor: NuSirt Biopharma

Sex: All·Age: 18 - 75

Code: NCT07647003·Phase 2

Guided Physical Activity Counseling for Hypertension in Primary Care

for Physical Activity

Sponsor: University of California, San Diego

Sex: All·Age: 18 - 80

Code: NCT07342543

Enhancing Mental and Physical Health of Women Veterans 3.0

for Cardiovascular Diseases

1 site in West Los Angeles

Sponsor: VA Office of Research and Development

Sex: All·Age: All ages

Code: NCT07356479

Evaluating the Effects of a Mindfulness Intervention on Health Outcomes in Individuals With Hypertension

for Hypertension

1 site in Columbus

Sponsor: Ohio State University

Sex: All·Age: 18+

Code: NCT07679984

INTEGRATE-RX: Integrating Clinical Pharmacists in HIV Care to Mitigate Last-Mile Challenges and Reduce Cardiovascular Disease Burden

for HIV

Sponsor: Temple University

Sex: All·Age: 18 - 75

Code: NCT07711366

Impact of Transcutaneous Spinal Stimulation on Blood Pressure and Orthostasis in Spinal Cord Injury

for Spinal Cord Injuries

1 site in West Orange

Sponsor: Kessler Foundation

Sex: All·Age: 18 - 75

Code: NCT07674511

Effectiveness of NeoMayor in Improving Cardiovascular Health

for Cardiovascular Health Status

Sponsor: University of Chile

Sex: All·Age: 55 - 75

Code: NCT07633392

SPIRO-First: A Pragmatic Primary Care-Embedded Pilot Trial of Renin-Guided First-Line Antihypertensive Therapy

for Hypertension

Sponsor: Ottawa Hospital Research Institute

Sex: All·Age: 18+

Code: NCT07687160·Phase 4

Micronutrient Enhancement for Development and Health in Adolescents - The MEDHA Study

for Neurodevelopment Outcome

Sponsor: Johns Hopkins Bloomberg School of Public Health

Sex: Female·Age: 10 - 18·Accepts healthy volunteers

Code: NCT07695883·Phase 3

Tailoring TM-HTN Intervention for Black Patients

for Hypertension

1 site in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06593119

Potatoes, Type 2 Diabetes, and Cardiometabolic Health

for T2D

1 site in Blacksburg

Sponsor: Virginia Polytechnic Institute and State University

Sex: All·Age: 50 - 70·Accepts healthy volunteers

Code: NCT07229482

Apply to this trial

Osilodrostat in Patients With Hypertension Caused by Hypercortisolaemia Due to Cushing's Syndrome

for Hypertension

Sponsor: RECORDATI GROUP

Sex: All·Age: 18+

Code: NCT07247162·Phase 4

Evaluation of a Novel Indoor Air Pollution Intervention Among Older Adults

for Cardiovascular Diseases

1 site in Missoula

Sponsor: University of Montana

Sex: All·Age: 55 - 79

Code: NCT07539987

Evaluating the Implementation Via Audit and Feedback

for Hypertension

Sponsor: Southern Medical University, China

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT07542587

The Impact of Low Sodium Salt Substitute Use on Serum Potassium Levels Among Patients With Hypertension

for Hypertension

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT07460882

Virtual Lifestyle Medicine Group Visits for High Blood Pressure

for Hypertension

1 site in Houston

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 18+

Code: NCT07698509

A Real-world Study of the Effectiveness of Angiotensin Receptor-Neprilysin Inhibitor Therapy in Hypertensive Patients in the United Arab Emirates

for Hypertension

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 99

Code: NCT07465666

Early Time-Restricted Eating for Cardiovascular Health

for Hypertension

1 site in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 60+

Code: NCT07634926

Faisalabad Initiative of Research and Management of NCDs

for Diabete Mellitus

Sponsor: Getz Pharma

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07676214

Blood Pressure Measured on the Arm With Different Layers of Clothing Versus on the Bare Arm in Patients at Grenoble Alpes University Hospital

for Blood Pressure

Sponsor: University Hospital, Grenoble

Sex: All·Age: 18+

Code: NCT07687771

Implementation of a Beauty Salon-Based Strategy for Blood Pressure Management Among Women

for Hypertension

1 site in Baltimore

Sponsor: Johns Hopkins University

Sex: Female·Age: 18 - 79·Accepts healthy volunteers

Code: NCT07042386

Apply to this trial

Fixed-Dose Combinations Pragmatic Randomized Implementation Trial for Blood Pressure Control

for Hypertension

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 80

Code: NCT07228065

Synthetic THC And Blood Pressure

for Blood Pressure

1 site in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 21 - 40

Code: NCT07231965·Phase 2, Phase 3

A Randomized Feasibility Trial Comparing Drospirenone and Norethindrone for Postpartum Hypertension Management in Preeclampsia

for Hypertension

1 site in Portland

Sponsor: Oregon Health and Science University

Sex: Female·Age: 18+

Code: NCT07293728·Phase 4

A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease

for Pulmonary Hypertension

3 sites incl. Houma

Sponsor: Pulnovo Medical, Inc.

Sex: All·Age: 18 - 85

Code: NCT07214376

Apply to this trial

Feasibility of a Community-Integrated Isometric Handgrip Exercise Program and Its Preliminary Effects on Blood Pressure and Cognitive Function in Older Adults

for Hypertension

Sponsor: McMaster University

Sex: All·Age: 65+

Code: NCT07648498

Optimizing Sustainable Cuff Access and Training Pathways for Self-Measured Blood Pressure Monitoring in Primary Care

for Hypertension

3 sites incl. Chicago

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT07693699

Wearable Blood-Pressure Monitoring Comparison Study

for Hypertension

Sponsor: Technische Universität Dresden

Sex: All·Age: 21 - 85

Code: NCT07719660

Does Erectile Dysfonction Allow to Evaluate Subendocardial Viability Among Treated Patients With Hypertension ?

for Hypertension

Sponsor: Assistance Publique - Hôpitaux de Paris

Sex: Male·Age: 18+

Code: NCT07719790

EIT Evaluation of Different Antihypertensive Agents on the Ventilation-Perfusion Ratio in Patients With Acute Respiratory Failure

for Acute Respiratory Failure (ARF)

Sponsor: First Affiliated Hospital of Wannan Medical College

Sex: All·Age: 18+

Code: NCT07603037

Community Blood Pressure Screening and Cardiovascular Risk Assessment in Croatia

for Hypertension

Sponsor: Dr. Josip Benčević General Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07670741

Effect of Secukinumab on Cardiorenal Outcomes in Patients With Cardiorenal Metabolic Syndrome and Atherosclerotic Cardiovascular Disease

for Cardiorenal Metabolic Syndrome

Sponsor: Peking University Third Hospital

Sex: All·Age: 18+

Code: NCT07704190·Phase 4

Lifestyle Intervention In CKD

for Chronic Kidney Disease

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT07633145

A Study to Evaluate Efficacy and Safety of HCP1803-4 in Patients With Essential Hypertension

for Hypertension

Sponsor: Hanmi Pharmaceutical Company Limited

Sex: All·Age: 19+

Code: NCT07660796·Phase 3

HJB647 Phase 1b Study in Japanese Healthy Participants With Elevated Blood Pressure and Patients With Hypertension

for Elevated Blood Pressure

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT07644364·Phase 1

Apply to this trial

Know Your Pressures NYC

for Glaucoma

1 site in New York

Sponsor: Columbia University

Sex: All·Age: 40+·Accepts healthy volunteers

Code: NCT05992415

Carotid-Femoral, Oscillometric and Estimated Pulse Wave Velocity

for Hypertension

Sponsor: Hospital de Base

Sex: All·Age: 18+

Code: NCT06836622

Clinical Decision Support Tool for the Treatment of Uncontrolled Hypertension

for Hypertension

1 site in Cleveland

Sponsor: The Cleveland Clinic

Sex: All·Age: 18+

Code: NCT07218198

Development of a Mobile Application Called TansiyoRitim for Hypertension Patients

for Hypertension

Sponsor: Kafkas University

Sex: All·Age: 18 - 85

Code: NCT07556419

IMPACT-HTN Study of Patients With Hypertension

for Hypertension (HTN)

2 sites incl. Palo Alto

Sponsor: Vivek Bhalla

Sex: All·Age: 18+

Code: NCT07579260

Cf-PWV and TyG Index Study

for Hypertension

Sponsor: Hospital de Base

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07589374

Reducing Inflammation to Improve Vascular and Bone Outcomes With Low-dose Colchicine in CKD

for Chronic Kidney Disease Mineral and Bone Disorder

1 site in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 69

Code: NCT07654231·Phase 2

Safety and Efficacy of Renal Denervation for Untreated Grade I Hypertension: a Pilot Study

for Hypertension

Sponsor: Ruijin Hospital

Sex: All·Age: 18 - 65

Code: NCT07664787

LLM-Assisted Diabetes and Hypertension Management by Village Doctors

for Type 2 Diabetes Mellitus

Sponsor: Jiangsu Taizhou People's Hospital

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT07678658

Polypills Approach for Multiple Cardiovascular Risk Factors

for Hypertension

Sponsor: China Medical University, China

Sex: All·Age: 50 - 75

Code: NCT07679828

A Randomized, Open-label, Two-arm, Two-period, Multiple-dose, Study to Evaluate Pharmacokinetic Drug-drug Interaction, Safety and Tolerability of UIC202601 and UIC202602 in Healthy Volunteers

for Hypertension

Sponsor: Korea United Pharm. Inc.

Sex: All·Age: 19 - 54·Accepts healthy volunteers

Code: NCT07682948·Phase 1

Apply to this trial

Feasibility Study: Continuous ECG and Blood Pressure Monitoring With the M2VS Sensor System

for Atrial Fibrillation (Paroxysmal)

Sponsor: University Hospital, Basel, Switzerland

Sex: All·Age: 18+

Code: NCT07694570

AI-Guided Predictions of Blood Pressure Dysregulation Using Perfusion Index as a Novel Biomarker in Persons With Spinal Cord Injury

for Spinal Cord Injuries (SCI)

1 site in The Bronx

Sponsor: James J. Peters Veterans Affairs Medical Center

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07699094

Apply to this trial

Reducing Heart Failure Risk in Late-Life With Physical Activity

for Hypertension

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT06247774

Effect of Counselling Using Lifestyle Medicine Assessment Tool on Hypertensive Patients

for Lifestyle Intervention

Sponsor: Indus Hospital and Health Network

Sex: All·Age: 18 - 65

Code: NCT07449962

A Study to Evaluate the Safety and Pharmacokinetics of AD-231 Compared to Coadministration of AD-231A, AD-231D and AD-231C

for Dyslipidemia

Sponsor: Addpharma Inc.

Sex: All·Age: 19 - 64·Accepts healthy volunteers

Code: NCT07590167·Phase 1

Hypertension (high blood pressure) clinical trials — common questions

Are hypertension (high blood pressure) clinical trials free to join?

Yes. Participating in a hypertension (high blood pressure) clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a hypertension (high blood pressure) clinical trial?

Each hypertension (high blood pressure) study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a hypertension (high blood pressure) trial near me?

Use the location controls above. We'll show recruiting hypertension (high blood pressure) trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many hypertension (high blood pressure) trials are recruiting right now?

We're currently tracking roughly 245 recruiting hypertension (high blood pressure) trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Hypertension (high blood pressure) trials by city

Birmingham, AL Chicago, IL Boston, MA Miami, FL San Francisco, CA Cleveland, OH Aurora, CO Bloomington, IN Detroit, MI Indianapolis, IN Ann Arbor, MI Boulder, CO

Related specialties

Cardiology Heart disease