Laryngopharyngeal Injury After Endotracheal Intubation Under General Anesthesia

Conditions

• Cholangiocarcinoma
• Gastric Cancer
• Hepatic Carcinoma
• Pancreatic Carcinoma
• Pulmonary Carcinoma
• Thyroid Carcinoma

Eligibility Criteria

Sex

ALL

Age

N/A - N/A

Healthy Volunteers

Not accepted

Study Details

This study retrospectively analyzed patients who underwent tracheal intubation under general anesthesia at the First Affiliated Hospital of Zhejiang University School of Medicine between October 1, 2015, and September 30, 2025, with a focus on issues related to postoperativelaryngopharyngeal complaints. Patients requiring otolaryngological consultation due to postoperative laryngopharyngeal complaints were identified via the case consultation system. Relevant patient data were collected through the Medison Anesthesia Information Management System and electronic medical record system, and telephone follow-up was conducted to assess patient prognosis. The primary outcome measures were the risk factors of postoperative hoarseness, while the secondary outcome measures included the incidence of postoperative hoarseness, the severity of vocal fold injury and its related risk factors. Additionally, the prognosis of patients and its related risk factors were evaluated. This study aims to reduce the incidence of perioperative laryngopharyngeal injury and provide a reference for the optimization of perioperative anesthetic regimens.

Key Dates

First listed

Jan 22, 2026

Start date

Nov 1, 2025

Status verified

Dec 2025

Primary completion

Dec 25, 2026

Completion

Dec 25, 2026

Study Design

Enrollment

1,200 participants (estimated)

Arms

• Arm: hoarseness
  We collected perioperative clinical data from the cohort, analyzed the associated risk factors for the occurrence of relevant symptoms, and investigated the prognosis.

Primary Outcome Measure

Postoperative hoarseness [ Time Frame: Perioperative,up to150 days ]

Central Contacts

• Diansan Su
  +8618616514088
  [email protected]

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