Gastric cancer Clinical Trials

Recruiting gastric cancer studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat gastric cancer. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting gastric cancer studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting gastric cancer trials

Within

Combination of CT and Ultrasound Radiomics Combined With Liquid Biopsy to Predict Neoadjuvant Chemotherapy Response in Patients With Locally Advanced Gastric Cancer

for Gastric Cancer

Sponsor: Liu Yang

Sex: All·Age: 18 - 80

Code: NCT07697079

Clinical Efficacy of Adebrelimab With or Without Apatinib Mesilate and SOX Neoadjuvant Therapy in Locally Advanced Gastric Cancer

for Gastric Cancer

Sponsor: Fujian Medical University

Sex: All·Age: 18 - 75

Code: NCT07314203·Phase 3

Neoadjuvant Intra-tumoral RP2 and FLOT in Gastroesophageal Adenocarcinoma

for Gastric Adenocarcinoma

1 site in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT07059611·Phase 2

Molecular Characterization of Tumor-Microenvironment Interactions to Predict Drug Resistance in Gastric and GEJ Adenocarcinoma

for Gastric Adenocarcinoma

Sponsor: Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis

Sex: All·Age: 18+

Code: NCT07692477

Sacituzumab Tirumotecan (Sac-TMT/SKB264) Plus Tagitanlimab (KL-A167) in Patients With Recurrent or Metastatic Esophageal Squamous Cell Carcinoma and Gastric/Gastroesophageal Junction Adenocarcinoma

for ESCC

Sponsor: Sun Yat-sen University

Sex: All·Age: 18+

Code: NCT07701681·Phase 2

Conversion Therapy With Retlirafusp Alfa Plus Chemotherapy in Gastric or Gastroesophageal Junction Adenocarcinoma

for Gastric Adenocarcinoma

Sponsor: Tang-Du Hospital

Sex: All·Age: 18 - 75

Code: NCT07709767·Phase 2

Comparison of Partial Stomach-Partitioning and Conventional Gastrojejunostomy for the Treatment of Gastric Outlet Obstruction in Advanced Gastric Cancer

for Gastric Cancer

Sponsor: Guangxi Medical University

Sex: All·Age: 18 - 75

Code: NCT07561073

Apply to this trial

Phase 1/2 Study of BHB810 in Advanced Gastric and GEJ Adenocarcinoma

for Gastric Cancer

1 site in Fairfax

Sponsor: BigHat Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT07529808·Phase 1, Phase 2

Apply to this trial

Study of Denikitug (GS-1811) Given Alone or With Nivolumab or Chemotherapy in Adults With Metastatic Gastric, Gastroesophageal Junction (GEJ), and Esophageal Adenocarcinomas

for HER2-negative

1 site in Boston

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT07546812·Phase 2

Apply to this trial

GI-05: The Impact of Olanzapine Among Patients Receiving Neoadjuvant Chemotherapy for Gastric Cancer

for Gastric Adenocarcinoma

1 site in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18+

Code: NCT07581405·Phase 2

Zanidatamab Combined With Chemotherapy as Neoadjuvant/Conversion Therapy for HER2-Positive (IHC 3+ or IHC 2+) Advanced Gastric or Gastroesophageal Junction Adenocarcinoma: a Phase II Open-Label Study

for Gastric Cancer

Sponsor: Zhifeng Zhao, PhD

Sex: All·Age: 18 - 75

Code: NCT07685704·Phase 2

Sac-TMT Combined With Fruquintinib as Second-Line Treatment in Patients With Advanced Gastric/Gastroesophageal Junction Adenocarcinoma

for Gastric Adenocarcinoma

Sponsor: Tianjin Medical University Cancer Institute and Hospital

Sex: All·Age: 18+

Code: NCT07689292·Phase 2

Becotatugvedotin Plus Pucotenlimab in EGFR-Positive Advanced Gastric/GEJ Adenocarcinoma

for Gastric Cancer

Sponsor: West China Second University Hospital

Sex: All·Age: 18 - 75

Code: NCT07692334·Phase 2

BREATH RESEARCH NARROW VALIDATION FOR GASTROINTESTINAL CANCER DETECTION

for Oesophageal Squamous Cell Carcinoma

Sponsor: Imperial College London

Sex: All·Age: 18+

Code: NCT07714538

Perioperative HLX10 (Serplulimab) With S-1+Oxaliplatin (SOX) in Locally Advanced and PD-L1-Positive Gastric or Esophagogastric Junction Adenocarcinoma

for Gastric Adenocarcinoma

Sponsor: National Cancer Center, Japan

Sex: All·Age: 18 - 80

Code: NCT07699939·Phase 2

A Multicentre Observational Cross-Sectional Study of The Gastric Precancerous Epithelial Pathway Using High-Definition Endoscopy And Histopathology In India

for Gastric Adenocarcinoma

Sponsor: Asian Institute of Gastroenterology, India

Sex: All·Age: 40+·Accepts healthy volunteers

Code: NCT07486518

HIPEC Priming Followed by Serplulimab Plus SOX/XELOX in Locally Advanced Gastric Cancer

for Locally Advanced Gastric Cancer

Sponsor: Shanghai Changzheng Hospital

Sex: All·Age: 18 - 75

Code: NCT07621484·Phase 2

Mannatide Combined With CAPOX and Tislelizumab for Advanced Gastric Cancer.

for Gastric Adenocarcinoma

Sponsor: Ming Liu

Sex: All·Age: 18 - 75

Code: NCT07655661·Phase 2

A Dose Optimization/Expansion Study of SAR445877 in Adult Chinese Participants With Advanced Gastric or Gastroesophageal Junction Cancer

for Gastric Cancer

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT07692204·Phase 2

Apply to this trial

Combination of Osemitamab (TST001), Pembrolizumab and Chemotherapy as First-line Therapy in Advanced or Metastatic GC/GEJ Adenocarcinoma

for Gastric Cancer

Sponsor: Suzhou Transcenta Therapeutics Co., Ltd.

Sex: All·Age: 18+

Code: NCT06093425·Phase 3

Total Neoadjuvant Therapy With Short Course Radiation Therapy in Gastric Cancer

for Gastric Cancer

4 sites incl. Los Angeles

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT07101666·Phase 2

Adaptive Adjuvant Therapy After Neoadjuvant Therapy and Gastrectomy for Gastric or Gastroesophageal Junction Adenocarcinoma

for Gastric Adenocarcinoma

Sponsor: Nanfang Hospital, Southern Medical University

Sex: All·Age: 18 - 75

Code: NCT07603349·Phase 2, Phase 3

A Study of ASP2138 Together With Chemotherapy and Pembrolizumab in Adults With Gastric Cancer

for Gastric Adenocarcinoma

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT07673887·Phase 3

A Study of SHY-ONC6, a Novel Proteasome Inhibitor, in Adults With Advanced or Metastatic Solid Tumors

for Advanced or Metastatic Solid Tumors

3 sites incl. Denver

Sponsor: SHY Therapeutics

Sex: All·Age: 18+

Code: NCT07705334·Phase 1

Apply to this trial

Objective Sleep Characteristics and Neoadjuvant Immunotherapy Response in Gastric/GEJ Cancer

for Gastric Adenocarcinoma

Sponsor: West China Second University Hospital

Sex: All·Age: 18+

Code: NCT07662005

Emotional Distress and Pathologic Response in Locally Advanced Gastric/GEJ Adenocarcinoma

for Gastric Adenocarcinoma

Sponsor: West China Second University Hospital

Sex: All·Age: 18+

Code: NCT07662070

Assessment of Adherence to Remotely Monitored Physical Activity Tracked on a Smartwatch, and Its Impact on Reducing Fatigue 3 Months After Adjuvant Chemotherapy for Cancer

for Breast Cancer

Sponsor: Centre Antoine Lacassagne

Sex: All·Age: 18 - 75

Code: NCT07429487

Prehabilitation in High-risk Oncologic Surgery

for Pancreatic Cancer

Sponsor: Fox Chase Cancer Center

Sex: All·Age: 18+

Code: NCT07638410

Perioperative Fruquintinib Combined With Sintilimab and SOX for Locally Advanced Gastric or GEJ Adenocarcinoma

for Gastric Adenocarcinoma

Sponsor: Sichuan University

Sex: All·Age: 18 - 75

Code: NCT07658872·Phase 2

Oral, Fecal and Intratumoral Microbiome Atlas in Colombian Patients With Advanced Solid Tumors Receiving First-Line Immunotherapy

for Gastric Cancer

Sponsor: Centro de Tratamiento e Investigación sobre Cáncer, Luis Carlos Sarmiento Angulo

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07676461

Apply to this trial

Tafolecimab Combined With Sintilimab and SOX in the Treatment of pMMR/MSS Gastric Cancer

for Gastric Adenocarcinoma

Sponsor: First Affiliated Hospital of Zhejiang University

Sex: All·Age: 18 - 75

Code: NCT07621562·Phase 2

Trial Comparing Standard of Care Therapy With and Without Sequential Cytoreductive Intervention for Patients With Metastatic Foregut Adenocarcinoma and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid (ctDNA) Levels

for Foregut Adenocarcinoma

1 site in New Haven

Sponsor: Yale University

Sex: All·Age: 18 - 80

Code: NCT07282912·Phase 2

Apply to this trial

Iparomlimab Tolvorlimab as Neoadjuvant Immunotherapy for Locally Advanced Gastric Adenocarcinoma With Microsatellite Instability/Mismatch Repair Deficiency

for Gastric Cancer

Sponsor: Peking University Cancer Hospital & Institute

Sex: All·Age: 18 - 75

Code: NCT07595523·Phase 2

A Study to Evaluate the Human Biodistribution and Dosimetry of the Radionuclide Labeled IR199 in Patients With Gastric Cancer and Pancreatic Cancer

for Gastric Cancer

Sponsor: Huashan Hospital

Sex: All·Age: 18+

Code: NCT07707531·EARLY_Phase 1

Apply to this trial

MRinRT: Swansea University and SWWCC Collaboration Study.

for Carcinoma

Sponsor: Swansea Bay University Health Board

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07365124

JS107 in Combination With Toripalimab and Chemotherapy for the Treatment of CLDN18.2-positive Gastric or Gastroesophageal Junction Adenocarcinoma

for Gastric Adenocarcinoma

Sponsor: NingBo Junyan Hongshi Biosciences Co., Ltd

Sex: All·Age: 18+

Code: NCT07584135·Phase 3

Apply to this trial

A Study of Cadonilimab Combined With Chemotherapy in People With Gastric or Gastroesophageal Junction Cancer

for Gastric Cancer

7 sites incl. Basking Ridge

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT07631000·Phase 2

Apply to this trial

Beta-Blockers on the Efficacy of Neoadjuvant Immunotherapy for Gastric Cancer

for Gastric Cancer

Sponsor: Nanfang Hospital, Southern Medical University

Sex: All·Age: 18 - 75

Code: NCT07511894·Phase 2

A Study Comparing BL-M05D1 With the Investigator's Choice of Treatment Regimen in Patients With Claudin (CLDN)18.2-Positive Advanced Gastric Cancer or Gastroesophageal Junction Adenocarcinoma (GC/GEJC) Who Have Received Prior First-Line Treatment

for Gastric Cancer

Sponsor: Sichuan Baili Pharmaceutical Co., Ltd.

Sex: All·Age: 18 - 75

Code: NCT07518147·Phase 3

Apply to this trial

PULSAR Combined With Immunotherapy for Unresectable Locally Advanced Gastric Cancer

for Gastric Adenocarcinoma

Sponsor: Samsung Medical Center

Sex: All·Age: 19+

Code: NCT07607119

Apply to this trial

Retlirafusp Alfa Combined With Apatinib and Nab-Paclitaxel as Second-line Treatment for Gastric or Gastroesophageal Junction Cancer

for Gastric Adenocarcinoma

Sponsor: Henan Cancer Hospital

Sex: All·Age: 18+

Code: NCT07610629·Phase 2

18F-FAPI PET/CT and MRI in Gastric Cancer

for Gastric Cancer

Sponsor: First Affiliated Hospital of Zhejiang University

Sex: All·Age: 20 - 80

Code: NCT07510867

Alternative Splicing Based Prediction of Chemotherapy Response in Gastric Cancer

for Gastric Cancer

1 site in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07587229

Apply to this trial

RCT Comparing Reduced-port Robotic and Conventional Laparoscopic Subtotal Gastrectomy

for Gastric Cancer

Sponsor: Yonsei University

Sex: All·Age: 20 - 85

Code: NCT07467174·Phase 4

A Study of Disitamab Vedotin, Tunlametinib, and PD-1 Antibody for Advanced Gastric Cancer

for Gastric Adenocarcinoma

Sponsor: Sun Yat-sen University

Sex: All·Age: 18+

Code: NCT07507526·Phase 2

A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers

for Colorectal Cancer

3 sites incl. Duarte

Sponsor: Dispatch Biotherapeutics

Sex: All·Age: 18+

Code: NCT07544589·Phase 1

Apply to this trial

Timing of Minimally Invasive Local Treatment After First-Line Systemic Therapy in Oligometastatic Esophageal or Gastric Adenocarcinoma

for Esophageal Cancer

Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Sex: All·Age: 18+

Code: NCT07000253·Phase 2, Phase 3

Apply to this trial

Non-Invasive Detection of claudin18.2 in Pancreatic and Gastric/Gastroesophageal Junction Cancer by [68Ga]Ga-NODAGA-SNA014 PET Imaging

for Pancreatic Cancer

Sponsor: Ruijin Hospital

Sex: All·Age: 18 - 75

Code: NCT07554742

Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors

for Solid Tumor

3 sites incl. Los Angeles

Sponsor: Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07517198·Phase 1

Apply to this trial

AI-assisted Decision-making of Reoperation for Postoperative Bleeding of Gastric Cancer

for Gastrectomy for Gastric Cancer

Sponsor: First Affiliated Hospital of Zhejiang University

Sex: All·Age: 18 - 90

Code: NCT07525765

Apply to this trial

SHR-1701 With or Without Apatinib in Combination With Chemotherapy as Neoadjuvant Therapy for Gastric Cancer

for Gastric Adenocarcinoma

Sponsor: The First Affiliated Hospital with Nanjing Medical University

Sex: All·Age: 18+

Code: NCT07464756·Phase 2

Apply to this trial

Comparison of Molecular-Genetic Concordance of the Primary Tumor and Brain Metastases of Gastroesophageal Cancers

for Gastric Cancer

Sponsor: Blokhin's Russian Cancer Research Center

Sex: All·Age: 18+

Code: NCT07464470

Apply to this trial

Dynamic ctDNA-Guided Adjuvant Therapy in cStage III and IVA Gastric or Gastroesophageal Junction Adenocarcinoma

for ctDNA

Sponsor: Fudan University

Sex: All·Age: 18 - 75

Code: NCT07507916·Phase 2

Magnetic Sentinel Lymph Node Mapping in Gastric Cancer

for Gastric Adenocarcinoma

1 site in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT05038098·Phase 1

AVA6103 in Subjects With Locally Advanced or Metastatic Selected Solid Tumors

for Vulvar Adenocarcinoma

3 sites incl. Grand Rapids

Sponsor: Avacta Life Sciences Ltd

Sex: All·Age: 18+

Code: NCT07454642·Phase 1

Apply to this trial

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

for NSCLC Adenocarcinoma

15 sites incl. Santa Rosa

Sponsor: IDEAYA Biosciences

Sex: All·Age: 18+

Code: NCT07277413·Phase 1

Apply to this trial

Application of Indocyanine Green Tracer in D2 Lymphadenectomy of Locally Advanced Gastric Cancer

for GASTRIC CANCER

Sponsor: Hospital of Navarra

Sex: All·Age: 18 - 85

Code: NCT06892392

Digital Rehabilitation for Gastric Cancer Surgery After Neoadjuvant Therapy

for Gastric Cancer

Sponsor: Beijing Friendship Hospital

Sex: All·Age: 18 - 70

Code: NCT07441850

Apply to this trial

[18F]FPyQCP PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications

for Colorectal Cancer

1 site in Dallas

Sponsor: Blue Earth Diagnostics

Sex: All·Age: 18 - 80

Code: NCT07432633·Phase 1, Phase 2

Apply to this trial

Comparison of the Postoperative Analgesic Effects of the Temperature-responsive Gel Mixed With Local Anesthetics Application and Ultrasound-guided Transversus Abdominis Plane Block in Patients Undergoing Laparoscopic Gastrectomy

for Gastric Cancer

Sponsor: Gyeong-Jo Byeon, MD, PhD

Sex: All·Age: 19+

Code: NCT07452471

Gastric cancer clinical trials — common questions

Are gastric cancer clinical trials free to join?

Yes. Participating in a gastric cancer clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a gastric cancer clinical trial?

Each gastric cancer study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a gastric cancer trial near me?

Use the location controls above. We'll show recruiting gastric cancer trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many gastric cancer trials are recruiting right now?

We're currently tracking roughly 109 recruiting gastric cancer trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Gastric cancer trials by city

Los Angeles, CA Duarte, CA Boston, MA Denver, CO Orange, CA Birmingham, AL Chicago, IL San Diego, CA San Francisco, CA Stanford, CA Anaheim, CA

Related specialties

Oncology GI oncology