The Association Between Deep Endometriosis and the Occurrence of Colorectal Carcinoma
- Sponsor
- University Medical Centre Ljubljana
- Study ID
- NCT07386431
- Status
- Not Yet Recruiting
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Conditions
- Bowel Endometriosis
- Carcinogenesis
- Colon Resection
- Colorectal Carcinoma
- Deep Endometriosis
- Endometriosis
- Endometriosis Pelvic
- Endometriosis Rectum
- Genetic Change
- Infertility
Eligibility Criteria
- Sex
- FEMALE
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Study Details
The goal of this study is to identify the molecular or genetic mechanisms that may predispose patients with bowel endometriosis to an increased risk of colorectal carcinoma. The study will include patients for whom surgical treatment of bowel endometriosis is clinically indicated. This research would represent a significant advancement in evaluating the necessity of surgical intervention in asymptomatic patients or those with mild symptoms. Furthermore, it would provide a broader insight into the systemic impact of endometriosis on other organ systems, ultimately improving risk assessment and preventive measures.
Key Dates
- First listed
- Feb 4, 2026
- Start date
- Feb 28, 2026
- Status verified
- Jun 2025
- Primary completion
- Oct 31, 2028
- Completion
- May 31, 2029
Study Design
- Enrollment
- 30 participants (estimated)
Primary Outcome Measure
Comparison of gene expression in healthy and with endometriosis affected bowel. [ Time Frame: 3 years ]
Central Contacts
- Rok Struna, MD+38631441111
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