A Study on Rosa Roxburghii for Knee Replacement Recovery

Sponsor
Shuguang Gao
Study ID
NCT07395856
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • Rosa roxburghii — DIETARY_SUPPLEMENT
    Enrolled patients will take 3g of Rosa roxburghii juice freeze-dried powder dissolved in 400-500ml of warm water with breakfast daily, starting from the day after surgery and continuing for 30 consecutive days.
  • Placebo — OTHER
    Starting from the first postoperative day, patients take placebo 3g/day after breakfast, dissolved in 200ml of warm water (40-50°C), for 4 consecutive weeks.

Study Details

This clinical trail is to investigates the effect of Rosa roxburghii juice freeze-dried powder on the recovery of patients undergoing total knee arthroplasty due to knee osteoarthritis. The participants are divided into an experimental group and a placebo group. Enrolled patients will take 3g of Rosa roxburghii juice freeze-dried powder or a placebo dissolved in 400-500ml of warm water with breakfast daily, starting from the day after surgery and continuing for 30 consecutive days. Data on inflammatory markers, oxidative stress indicators, and knee function scores will be collected from the participants one day before surgery, as well as on the first, third, and thirtieth days after surgery.

Key Dates

First listed
Feb 9, 2026
Start date
Jan 15, 2026
Status verified
Feb 2026
Primary completion
Jan 15, 2027
Completion
Feb 15, 2027

Study Design

Enrollment
184 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Rosa roxburghii
  • Placebo Comparator: placebo

Primary Outcome Measure

Oxidative Stress Markers [ Time Frame: Preoperative 24 hours, postoperative 24 hours, postoperative 72 hours, and postoperative 4 weeks. ]

Central Contacts

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