Comparison of Skin Closure Techniques in Oncological Neurosurgical Procedures: Intradermal Running Suture Versus Transdermal Interrupted Sutures

Sponsor
Medical University of Warsaw
Study ID
NCT07413796
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Absorbable running intradermal suture — OTHER
    Absorbable sutures used to perform continuous/running intradermal skin closure.
  • Non-absorbable interrupted transdermal suture — OTHER
    Non-absorbable sutures used to perform interrupted transdermal skin closure.

Study Details

The purpose of this study is to compare two commonly used methods of closing the skin after surgery for an intracranial tumor. Skin closure is one of the most important steps in neurosurgical procedures, as it has a major influence on how well the wound heals. In patients with brain tumors, proper wound healing is especially important because it may affect how soon additional treatments, such as radiotherapy or chemotherapy, can be started. There are different ways to close the skin after surgery, including running sutures and interrupted sutures. Both methods are widely used and considered safe. However, in oncological neurosurgery, there is limited scientific evidence comparing their effects, and the choice of technique is often based on the surgeon's personal experience. In this study, investigators will compare skin closure using running absorbable sutures with interrupted non-absorbable sutures. Investigators will evaluate how well, depending on used suturing methods, the wound heals and how often wound-related complications occur, such as infection, separation of the wound edges, or leakage of cerebrospinal fluid. Investigators believe that the results of this study will help improve wound care in patients undergoing neurosurgical treatment for brain tumors and, as a result, may contribute to better recovery and overall quality of life.

Key Dates

First listed
Feb 17, 2026
Start date
Feb 1, 2026
Status verified
Jan 2026
Primary completion
Feb 29, 2028
Completion
May 31, 2028

Study Design

Enrollment
382 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Subjects receiving absorbable running intradermal sutures
  • Active Comparator: Subjects receiving non-absorbable interrupted transdermal sutures

Primary Outcome Measure

Occurrence of surgical wound healing complication. [ Time Frame: From enrollment to the final wound assessment time point - 90 days postoperatively. ]

Central Contacts

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