Neuro-oncology Clinical Trials
Recruiting neuro-oncology studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.
Clinical trials study new ways to prevent, detect, or treat neuro-oncology. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting neuro-oncology studies with sites across the US; use the location tools to find ones near you.
What to expect
- Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
- Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
- No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.
Recruiting neuro-oncology trials
Study of Relatlimab and Nivolumab (Opdualag) in Replication Repair Deficient HGG and DIPG
FPS-ZM1 With or Without Dexamethasone for Controlling Post Operative Cerebral Edema in Patients With Glioblastoma
Disulfiram/Copper Combination In The Treatment of Newly Diagnosed Glioblastoma Multiform
CM93 Treatment in Subjects With Epidermal Growth Factor Receptor (EGFR)-Modified Recurrent Glioblastoma (rGBM)
NG101m Adjuvant Therapy in Glioblastoma Patients
ctDNA-Guided Intraventricular Therapy for CNS Malignancies
OLIG2 Inhibitor CT-179 for Recurrent and Newly-diagnosed Glioblastoma
Tear Fluid for the Detection of Tumor-associated Extracellular Vesicles in Glioblastoma Patients
PH Weighted Chemical Exchange Saturation Transfer MRI-Based Surgical Resection to Improve Survival in Patients With Glioblastoma
Study of Tovorafenib in High-Grade Glioma and Diffuse Intrinsic Pontine Glioma (DIPG)
A Study for Cerebral Open Flow Microperfusion
Pilot Radioembolisation Clinical Trial Assessing Safety and Efficacy in Recurrent Glioma
Feasibility Assessment of a Medical Device for Tumour Cell Retention and Radiotherapy Sensitization in Patients With Suspected High-grade Glioma
Musical Training: Promoting Brain Function in Children Who Have Survived Brain Tumours
Clinical Benefit of 18F-FET in Glioma.
Adebrelimab Plus Temozolomide ± Hyperbaric Oxygen for Primary Glioblastoma
B7-H3.CD28Z.CART in CNS Neoplasms
Monitoring of Neurological Symptoms, Treatment Tolerance, and Quality of Life Using the Resilience PRO Electronic Patient-reported Outcome Application in Patients With IDH-mutated Glioma
Survivin-Targeted Dendritic Cell (DC) Cell Injection for Newly Diagnosed Glioblastoma
Positron Emission Tomography/Computed Tomography (PET/CT) Imaging in Patients Diagnosed With a Glioma
Multiparametric Metabolic and Hypoxic PET/MRI Imaging Substudy in Gliomas
University of Kentucky Markey Cancer Center Neuro-Oncology Multi-Disciplinary Tumor Board Protocol for the Treatment of Advanced Brain Metastases
Cerebral Connectivity and Metabolic Phenotype of Gliomas: Prospective Addition of DTI and Rs-fMRI to a Preoperative FDG PET Strategy, With Neuropsychological Correlates and Post-treatment Follow-up
Evaluating Biomarkers of Cognitive Dysfunction in Patients With Cancer
A Phase I First-in-human Trial of Bvax (B-cell Vaccination) in Addition to Standard of Care Chemoradiotherapy for Newly Diagnosed Glioblastoma
Movie-Watching Functional MRI for Mapping Brain Function in Neurosurgical Patients
Neurocognitive Assessment CNSL and LGG
Levetiracetam Extended-Release Plus Stupp Protocol for Hypoxic IDH-Wildtype Glioblastoma
Evaluation of the Distribution of 64Cu/68Ga Labeled CM500 in Healthy Volunteers and Patients With Cancer
Panitumumab-IRDye800 to Detect Pediatric Neoplasms During Neurosurgical Procedures
Asciminib With or Without Sildenafil for Brain Tumors
Language Network Prehab Via fMRI Neurofeedback
Laser Interstitial Thermal Therapy (LiTT) With Cemiplimab or Other Chemotherapy in Recurrent Glioblastomas
Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).
A Study for Postoperative Delirium in Older Patients With Intracranial Tumors
A Phase1 Clinical Trial Evaluating Locoregional Delivery Of Engineered NK Cells Containing IL13Ra And EGFvIII Chimeric Antigen Receptor (CAR), IL-21 Secretion And Deleted TGF-BetaR2 And NR3C1 In Recurrent Glioblastoma
Irinotecan-ChemoSeed in Surgically Resectable Glioblastoma
BRiTE - Bispecific T Cell Engager for Patients With Glioblastoma
STUPP Regimen With or Without Lenvatinib for Newly Diagnosed Glioblastoma With MGMT Promoter Methylation
A Study Using Brain Stimulation and Behavioral Therapy to Increase Extent of Resection in Low-Grade Gliomas
MeDex: No Perioperative Dexamethasone in Brain Metastases
EEG-Guided Cognitive Function Preservation in Patients With Brain Tumors
Pilot Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Intracranial Lesions During Neurosurgical Procedures
IL-8 Receptor Modified Patient-Derived Activated CD70 CAR T Cell Therapy in Adults With Brain Metastases
A Phase 1/2 Study of Safety and Tolerability of MT-125 With Chemoradiation in Patients With Newly Diagnosed MGMT Methylated Glioblastoma
Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG
Glioma Adaptive Radiotherapy With Development of an Artificial Intelligence Workflow
DEXmedetomidine for Postoperative Analgesia and Delirium Prevention After NEUROsurgery (DEX-NEURO Trial)
Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma
AI-Assisted MRI Molecular Subtyping in Pediatric Brain Tumors
Memory Avoidance Whole Brain Radiotherapy vs Hippocampal Avoidance Whole Brain Radiotherapy (Athena 2 Trial)
A Clinical Trial Evaluating the Tolerability, Safety, and Preliminary Efficacy of NRG-103 Injection in Patients With Recurrent or Progressive High-grade Glioma
Phase I Trial of pH Resections of GBM at VA
Home-based Vision Rehabilitation Guided by Brain Imaging
Trastuzumab Deruxtecan + Stereotactic Radiosurgery (SRS) in HER2+ Breast Cancer Brain Metastases
Oral Gallium Maltolate for Recurrent Glioblastoma
Living Well With Brain Cancer: A Group-Based Intervention to Promote Whole-Person Well-Being
VorAsidenib With Lomustine In Patients With rEcurrent IDH-mutaNT Glioma Harboring IDH1 and/or IDH2 Mutations
Evaluation of [⁶⁸Ga/¹⁷⁷Lu]HT547: Safety, Biodistribution, and Dosimetry in Solid Tumors
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Neuro-oncology clinical trials — common questions
Are neuro-oncology clinical trials free to join?
Yes. Participating in a neuro-oncology clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.
Who can join a neuro-oncology clinical trial?
Each neuro-oncology study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.
How do I find a neuro-oncology trial near me?
Use the location controls above. We'll show recruiting neuro-oncology trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.
How many neuro-oncology trials are recruiting right now?
We're currently tracking roughly 370 recruiting neuro-oncology trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.
Looking for a specific location? Browse trials by city and state.