Project Q: Cue-based Treatment Intervention to Promote Cessation Among People Who Smoke Lightly or Non-daily

Part of paid clinical trials in Durham, North Carolina.

Sponsor
Duke University
Study ID
NCT07425119
Status
Recruiting
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Conditions

  • Tobacco Use Disorder

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Cognitive Behavioral Therapy (CBT) — BEHAVIORAL
    CBT delivered via telehealth sessions and supportive text messages.
  • Cue-based treatment intervention — BEHAVIORAL
    Cue-based treatment includes exposure to smoking-related cues and coping strategies.

Study Details

This study aims to test the feasibility and acceptability of a remotely delivered cue-based treatment intervention to promote smoking cessation among people who smoke lightly or non-daily. Secondary objectives include assessing preliminary efficacy on cessation and examining cue reactivity. Participants will be randomized to CBT only or CBT + cue-based treatment, with assessments at baseline, end-of-treatment, 6 months, and 12 months.

Key Dates

First listed
Feb 20, 2026
Start date
Jul 7, 2026
Status verified
Jul 2026
Primary completion
Jan 31, 2028
Completion
Jun 30, 2028

Study Design

Enrollment
60 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: CBT only
    CBT delivered via telehealth sessions and supportive text messages.
  • Experimental: CBT + Cue-based treatment
    CBT plus cue-based treatment includes exposure to smoking-related cues and coping strategies.

Primary Outcome Measure

Feasibility as measured by the number of participants who are recruited and randomized [ Time Frame: During the recruitment period (up to 9 months) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Duke UniversityDurhamNorth Carolina27701
Laura Fish, PhD
[email protected]
9196813820
Lauren Hart, MPH, MSW
[email protected]
Laura Fish, PhD (PRINCIPAL_INVESTIGATOR)

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