Dose-Response Effect of Phosphatidylserine on eSport Performance

Part of paid clinical trials in Saint Charles, Missouri.

Sponsor
Lindenwood University
Study ID
NCT07533032
Status
Completed

Conditions

  • Cognitive Function
  • Gaming Performance

Eligibility Criteria

Sex
ALL
Age
18 Years - 40 Years
Healthy Volunteers
Accepted

Interventions

  • Placebo — DIETARY_SUPPLEMENT
    Participants will ingest a placebo supplement daily for 6 weeks. The supplement will be consumed with approximately 8 ounces of water at a consistent time each day.
  • Phosphatidylserine (100 mg) — DIETARY_SUPPLEMENT
    Participants will ingest 100 mg of phosphatidylserine daily for 6 weeks. The supplement will be consumed with approximately 8 ounces of water at a consistent time each day.
  • Phosphatidylserine (200 mg) — DIETARY_SUPPLEMENT
    Participants will ingest 200 mg of phosphatidylserine daily for 6 weeks. The supplement will be consumed with approximately 8 ounces of water at a consistent time each day.

Study Details

This study will evaluate the effects of daily phosphatidylserine supplementation on electronic gaming performance, cognitive function, sleep quality, stress-related outcomes, and autonomic responses in healthy adult gamers. Participants will be enrolled in a randomized, double-blind, placebo-controlled, parallel-group study and assigned to receive placebo, 100 mg phosphatidylserine, or 200 mg phosphatidylserine daily for 6 weeks. Outcome measures will be assessed at baseline, Week 3, and Week 6 and will include electronic gaming performance, cognitive function, visual analog scale ratings, sleep quality questionnaires, hemodynamic responses, and heart rate variability. The study is designed to determine whether daily phosphatidylserine supplementation can improve performance and selected physiological and psychological outcomes during prolonged electronic gaming sessions.

Key Dates

Start date
Jun 15, 2021
Status verified
Mar 2026
Primary completion
Apr 14, 2025
Completion
Apr 14, 2025

Study Design

Enrollment
80 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Placebo Comparator: Placebo Comparator
    Participants assigned to this group will ingest a placebo supplement daily for 6 weeks. All participants will complete identical testing procedures at baseline (Week 0), Week 3, and Week 6.
  • Experimental: Phosphatidylserine (100 mg)
    Participants assigned to this group will ingest 100 mg of phosphatidylserine daily for 6 weeks. All participants will complete identical testing procedures at baseline (Week 0), Week 3, and Week 6.
  • Experimental: Phosphatidylserine (200 mg)
    Participants assigned to this group will ingest 200 mg of phosphatidylserine daily for 6 weeks. All participants will complete identical testing procedures at baseline (Week 0), Week 3, and Week 6.

Primary Outcome Measure

Gaming Performance Score [ Time Frame: Change from baseline (Week 0) to Week 6 ]

Locations (1)

FacilityCityStateZIPSite coordinators
Lindenwood University Exercise and Performance Nutrition LaboratorySaint CharlesMissouri63301-

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