Paid Clinical Trials in Saint Charles, MO
As of July 2026, 31 paid clinical trials are recruiting in Saint Charles, Missouri. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Saint Charles offers studies at sites including Midwest Research Group for conditions such as Major Depressive Disorder, Schizophrenia, Bipolar I Disorder, Binge-Eating Disorder. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Saint Charles
Trials by drug in Saint Charles
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26 clinical trials
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients
Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum Disorder
Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder in Pediatric Patients
Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder
A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder
A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)
Study to Evaluate Weight Gain as Assessed by Change in BMI Z-score in Pediatric Subjects With Schizophrenia or Bipolar I Disorder
A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
A Study to Evaluate Solrikitug in Participants With COPD (ZION)
Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)
RE104 Safety and Efficacy Study in Generalized Anxiety Disorder
ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response
NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
A Clinical Trial to Assess the Efficacy, Safety, and Tolerability of a Repeat Dose of Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety Disorder
A Pilot Study to Evaluate the Ability of Lactoferrin to Modulate Iron Homeostasis and Exercise Performance in Exercising Females
Dose-Response Impact of Geranylgeraniol (GG) Supplementation on Muscle Health
Impact of Weizmannia (Bacillus) Coagulans JBI-YZ6.3 on Gut Health and Fecal Microbiome Changes
Dose-Response Impact of Glucosyl-Hesperidin (CitraPeak) on Exercise Performance, Blood Flow, Stress, Cognition, and Other Perceptual Indicators
Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol
Randomized Withdrawal Study in Patients With Schizophrenia
Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder
A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
Top Research Study Locations in Saint Charles
Researchers run research studies in Saint Charles, MO at 16 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Midwest Research Group | Bipolar Depression, Generalized Anxiety Disorder, Irritability Associated With Autism Spectrum Disorder | 5 |
| Exercise and Performance Nutrition Laboratory | Exercise Metabolism, Exercise Performance, Exercise Performance of Fit Athletes | 3 |
| Lindenwood University | Blood Flow, Cognitive Function, Constipation | 2 |
| Midwest Chest Consultants | COPD, Chronic Obstructive Pulmonary Disease | 2 |
| Neurocrine Clinical Site | Major Depressive Disorder | 2 |
| St. Charles Psychiatric Associates - Midwest Research Group | Major Depressive Disorder | 2 |
| Vanda Investigational Site | Major Depressive Disorder (MDD), Schizophrenia | 2 |
| Saint Charles Psychiatric Associates | Generalized Anxiety Disorder (GAD), Bipolar I Disorder, Bipolar II Disorder | 2 |
| Alkermes Investigational Site | Bipolar I Disorder, Schizophrenia | 1 |
| Alkermes Investigator Site | Bipolar I Disorder, Schizophrenia | 1 |
| Autobahn | Major Depressive Disorder | 1 |
| Lindenwood University Exercise and Performance Nutrition Laboratory | Body Composition, Muscle Health, Muscle Strength | 1 |
| Midwest Research Group 1 | Autism Spectrum Disorder, Bipolar Disorder, Schizophrenia | 1 |
| SSM Health St Joseph Hospital St Charles | Lumbar Spinal Stenosis | 1 |
| St. Charles Psychiatric Associates, Inc. dba Midwest Research Group | Depressive Disorder, Treatment-Resistant, Major Depressive Disorder (MDD) | 1 |
| Vistagen Clinical Site | Social Anxiety Disorder | 1 |
Active & Upcoming Studies in Saint Charles (2026)
Recruiting trials in Saint Charles grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Mental health & behavior (10 active studies)
- RE104 Safety and Efficacy Study in Generalized Anxiety Disorder · Phase 2 · Reunion Neuroscience Inc
- A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder · Phase 2 · AbbVie
Common conditions studied in Saint Charles
- Major Depressive Disorder (6 active studies)
- Schizophrenia (4 active studies)
- Bipolar I Disorder (3 active studies)
- Binge-Eating Disorder (2 active studies)
- Exercise Performance (2 active studies)
- Gastrointestinal Symptoms (2 active studies)
Leading research sponsors in Saint Charles
- Lindenwood University
- Axsome Therapeutics, Inc.
- Intra-Cellular Therapies, Inc.
- AbbVie
- Alkermes, Inc.
Frequently asked questions
How many paid clinical trials are currently recruiting in Saint Charles?
There are approximately 31 recruiting clinical trials in Saint Charles, Missouri listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Saint Charles pay participants?
Most recruiting trials in Saint Charles compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Saint Charles?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Saint Charles?
The most common conditions under active study in Saint Charles include Major Depressive Disorder (6), Schizophrenia (4), Bipolar I Disorder (3), Binge-Eating Disorder (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Saint Charles?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Saint Charles on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Saint Charles?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Saint Charles?
Recruiting research sites in Saint Charles include Midwest Research Group, Exercise and Performance Nutrition Laboratory, Lindenwood University, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Saint Charles right now?
The largest active categories in Saint Charles are Mental health & behavior (10). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.