Comparative Study on the Medium- and Long-term Benefits of Prosthesis Selection in Total Knee Arthroplasty

Sponsor
Second Affiliated Hospital of Wenzhou Medical University
Study ID
NCT07553871
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Study Details

This retrospective real-world study aims to compare the medium- and long-term clinical outcomes, safety, and economic benefits of different knee prosthesis brands used in primary unilateral total knee arthroplasty (TKA) at our hospital. The study will include adult patients who underwent first-time unilateral TKA between January 1, 2022 and December 31, 2025. Outcomes such as postoperative knee function, complications, length of hospital stay, quality of life, and medical costs will be evaluated. The results are expected to provide evidence to support prosthesis selection and optimize healthcare resource allocation.

Key Dates

First listed
Apr 28, 2026
Start date
May 31, 2026
Status verified
Apr 2026
Primary completion
Dec 31, 2026
Completion
Dec 31, 2030

Study Design

Enrollment
3,500 participants (estimated)

Arms

  • Arm: Mainstream Prosthesis Cohort
    Patients who underwent first-time unilateral primary total knee arthroplasty (TKA) using established mainstream prosthesis brands during the study period.
  • Arm: Emerging Prosthesis Cohort
    Patients who underwent first-time unilateral primary total knee arthroplasty (TKA) using emerging prosthesis brands during the study period.

Primary Outcome Measure

Knee Function Score at 1 Year After Surgery [ Time Frame: 1 year after surgery ]

Central Contacts

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