The Effect of Lipedema on Knee Osteoarthritis

Sponsor
Izmir Democracy University
Study ID
NCT07575555
Status
Recruiting
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Conditions

  • Knee
  • Knee Acute and Chronic Pain
  • Knee Arthritis Osteoarthritis
  • Knee Arthropathy
  • Knee Cartilage Defects
  • Knee Cartilage Lesions
  • Knee Osteoarthritis
  • Lipedema

Eligibility Criteria

Sex
FEMALE
Age
30 Years - 65 Years
Healthy Volunteers
Not accepted

Study Details

This study will be one of the few to examine the effect of lipedema on knee osteoarthritis in a comparative manner with a control group within the same osteoarthritis context. Although the relationship between obesity and osteoarthritis has been extensively studied in the literature, the effect of specific adipose tissue pathologies, such as lipedema, on osteoarthritis has not been sufficiently investigated. This study aims to demonstrate the independent effect of lipedema on osteoarthritis, evaluate clinical and ultrasonographic parameters together, and contribute to early diagnosis and targeted rehabilitation strategies.

Key Dates

First listed
May 8, 2026
Start date
Jul 7, 2026
Status verified
Jul 2026
Primary completion
Jul 15, 2027
Completion
Aug 15, 2027

Study Design

Enrollment
76 participants (estimated)

Arms

  • Arm: Group 1
    Knee osteoarthritis with lipedema
  • Arm: Group 2
    Knee osteoarthritis without lipedema

Primary Outcome Measure

Ultrasonography-based measurements of femoral cartilage thickness [ Time Frame: Day 1 ]

Central Contacts

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