Post-op Prednisone and Glucose Monitoring in TKA

Part of paid clinical trials in New York, New York.

Sponsor
Columbia University
Study ID
NCT07630896
Phase
PHASE4
Status
Not Yet Recruiting

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Conditions

  • Osteoarthritis
  • Total Hip Arthroplasty (THA)
  • Unicompartmental Knee Arthroplasty

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Prednisone — DRUG
    40 mg daily for 5 days
  • Continuous Glucose Monitor — DEVICE
    Provides real-time glucose readings for up to 14 days
  • InkWell Health Tattoos — OTHER
    Temporary medical-grade tattoos that provide real-time monitoring of knee swelling and range of motion

Study Details

This study compares the efficacy of a 5-day post-operative oral prednisone regimen (40 mg daily) with the standard intraoperative steroid regimen, focusing on pain, swelling, range of motion, opioid use, and glucose levels monitored continuously.

Key Dates

Start date
Jul 1, 2026
Status verified
Jun 2026
Primary completion
Dec 31, 2027
Completion
Mar 31, 2028

Study Design

Enrollment
104 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Post-operative Steroids
    Participants will receive a 5-day regimen of 40 mg oral prednisone postoperatively.
  • Placebo Comparator: Standard of care
    Participants will receive standard of care treatment, consisting of the intravenous administration of dexamethasone and periarticular administration of steroids intraoperatively.

Primary Outcome Measure

Pain at Rest [ Time Frame: 2 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIP
Columbia University Irving Medical CenterNew YorkNew York10032

Find similar trials in New York, NY

By condition
Osteoarthritis (other)
By specialty
OrthopedicsMusculoskeletal disorders
By research site
Columbia University Irving Medical Center· New York, NY

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