Self-directed Mobile Mindfulness to Address ICU Survivors' Psychological Distress: the Lift RCT

Part of paid clinical trials in Los Angeles, California.

Sponsor
Duke University
Study ID
NCT07634419
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Lift mobile mindfulness — BEHAVIORAL
    Mobile app-based mindfulness program for serious illness survivors
  • Enlighten Recovery education program — BEHAVIORAL
    Mobile app-based critical illness education program for serious illness survivors

Study Details

Serious acute heart and lung illnesses like heart failure, severe COVID, and sepsis often leave survivors struggling not only physically, but also with lasting depression, anxiety, and stress. These problems that are hard to treat because access to mental health care is often limited. To help address this, the researchers created Lift, a fully automated mindfulness program designed with patient input and delivered through a mobile app. The investigators now plan a large, multi-site study to test whether Lift improves mental health and quality of life over six months compared to a critical illness education program called Enlighten Recovery. Overall the goal is to make an easy-to-use, widely accessible program available to people across the U.S., including those who speak Spanish.

Key Dates

Start date
Jun 1, 2026
Status verified
May 2026
Primary completion
Feb 28, 2031
Completion
May 31, 2031

Study Design

Enrollment
450 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE

Arms

  • Experimental: Lift mobile mindfulness
    Mobile app-based mindfulness program
  • Active Comparator: Enlighten Recovery education program
    Mobile app-based critical illness education program

Primary Outcome Measure

Patient Health Questionnaire 9-item depression scale (PHQ-9) [ Time Frame: Baseline to 1 month ]

Central Contacts

Locations (3)

FacilityCityStateZIP
Cedars-Sinai Medical CenterLos AngelesCalifornia90048
Duke University Medical CenterDurhamNorth Carolina27710
Medical University of South CarolinaCharlestonSouth Carolina29403

Find similar trials in Los Angeles, CA

By condition
Heart failure
By specialty
CardiologyHeart disease
By research site
Cedars-Sinai Medical Center· Los Angeles, CADuke University Medical Center· Durham, NCMedical University of South Carolina· Charleston, SC

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