A Study of Lower Dose Radiation Therapy for People With Prostate Cancer

Part of paid clinical trials in Basking Ridge, New Jersey.

Sponsor
Memorial Sloan Kettering Cancer Center
Study ID
NCT07635238
Phase
PHASE2
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
MALE
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • MR-guided Stereotactic Body Radiation Therapy — RADIATION
    MR-guided 2 fraction Stereotactic Body Radiation Therapy

Study Details

The purpose of this study is to see whether giving a lower (de-escalated) dose of radiation therapy to some parts of the prostate can reduce side effects compared to giving the same (uniform) dose of radiation therapy to the whole prostate.

Key Dates

Start date
May 28, 2026
Status verified
May 2026
Primary completion
May 28, 2030
Completion
May 28, 2030

Study Design

Enrollment
54 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Group 1: Uniform dose SBRT
  • Experimental: Group 2: De-escalated dose SBRT

Primary Outcome Measure

Number of participants with acute GU toxicities [ Time Frame: 12 weeks from the start of radiation therapy ]

Central Contacts

Locations (7)

FacilityCityStateZIPSite coordinators
Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities)Basking RidgeNew Jersey07920
Victoria Brennan, MBBCH BAO
[email protected]
212-639-8904
Memorial Sloan Kettering at Monmouth (Limited Protocol Activities)MiddletownNew Jersey07748
Victoria Brennan, MBBCH BAO
[email protected]
212-639-8904
Memorial Sloan Kettering at Bergen (Limited Protocol Activities)MontvaleNew Jersey07645
Victoria Brennan, MBBCH BAO
[email protected]
212-639-8904
Memorial Sloan Kettering at Suffolk-Commack (Limited Protocol Activities)CommackNew York11725
Victoria Brennan, MBBCH BAO
[email protected]
212-639-8904
Memorial Sloan Kettering at Westchester (Limited Protocol Activities)HarrisonNew York10604
Victoria Brennan, MBBCH BAO
[email protected]
212-639-8904
Memorial Sloan Kettering Cancer Center (All Protocol Activities)New YorkNew York10065
Victoria Brennan, MBBCH BAO
212-639-8904
Memorial Sloan Kettering at Nassau (Limited Protocol Activities)UniondaleNew York11553
Victoria Brennan, MBBCH BAO
[email protected]
212-639-8904

Find similar trials in Basking Ridge, NJ

By condition
Prostate cancer
By specialty
OncologyProstate oncologyMen's healthUrology
By research site
Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities)· Basking Ridge, NJMemorial Sloan Kettering at Monmouth (Limited Protocol Activities)· Middletown, NJMemorial Sloan Kettering at Bergen (Limited Protocol Activities)· Montvale, NJMemorial Sloan Kettering at Suffolk-Commack (Limited Protocol Activities)· Commack, NYMemorial Sloan Kettering at Westchester (Limited Protocol Activities)· Harrison, NYMemorial Sloan Kettering Cancer Center (All Protocol Activities)· New York, NY

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