Men's health Clinical Trials

Recruiting men's health studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat men's health. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting men's health studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting men's health trials

Within

PROstate Cancer Risk Calculator for ACTionable Clinical Decision-making in Nigeria

for Prostate Cancer

Sponsor: Ahmadu Bello University

Sex: Male·Age: 18+·Accepts healthy volunteers

Code: NCT07733440

A Phase 1/2 Study of Personalized PSMA Radiopharmaceutical Therapy

for Cancer

Sponsor: CHU de Quebec-Universite Laval

Sex: All·Age: 18+

Code: NCT05896371·Phase 1, Phase 2

A Point of Prostate Cancer Diagnosis Virtual Reality Assistant Intervention in Supporting Newly Diagnosed Black Men

for Prostate Carcinoma

1 site in Jacksonville

Sponsor: Mayo Clinic

Sex: Male·Age: All ages

Code: NCT07126548

Defining the Safety and Efficacy of POSterIor Tibial NeRve StimulatiON in Children

for Overactive Bladder

Sponsor: Chi Dang Hornik

Sex: All·Age: 5 - 21·Accepts healthy volunteers

Code: NCT06769854·Phase 4

iCCARE Project #4: Grounded Theory Study of the Social Determinants of Migrant Health Factors Impacting Prostate Cancer Care and Survivorship Among Sub-Saharan African and Caribbean Immigrant Men Diagnosed With Prostate Cancer

for Prostate Cancer

1 site in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: Male·Age: 18+

Code: NCT07105020

Weekly Online CT or MR Adaptive Definitive SBRT for Regionally Metastatic Prostate Cancer

for Prostate Cancer

Sponsor: University of Zurich

Sex: Male·Age: 18+

Code: NCT07591051

Quality and Safety of Real-Time Brachytherapy Treatments: Clinical Implementation of a Multipoint Scintillation Detector for Treatment Monitoring

for Prostate Cancer

Sponsor: CISSS de Chaudière-Appalaches

Sex: All·Age: 18+

Code: NCT07580651

Male Pelvic Floor Muscle Rehabilitation Exercises

for Erectile Dysfunction

Sponsor: Dream Video LLC

Sex: Male·Age: 18 - 60·Accepts healthy volunteers

Code: NCT07451808

Training on Systemic and Organ Spec. PM in PC

for Prostate Cancer

1 site in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07768917

Evaluating Treatment Outcomes Using Darolutamide and Androgen Deprivation Therapy in Patients With Metastatic Hormone-Sensitive Prostate Cancer.

for Prostate Cancer

1 site in Chicago

Sponsor: University of Chicago

Sex: Male·Age: 18+

Code: NCT06660862·Phase 4

Gene-edited T Regulatory Cells (CRG-150) for the Treatment of Relapsed/Refractory Malignancies

for HR-positive, HER2-negative Breast Cancer

Sponsor: CoRegen, Inc.

Sex: All·Age: 18+

Code: NCT07730125·Phase 1, Phase 2

Sipuleucel-T (Sip-T) in Combination With N-803 in Metastatic Androgen Pathway Modulation Resistant (mAPMR) Prostate Cancer

for Prostate Cancer

1 site in St Louis

Sponsor: Washington University School of Medicine

Sex: Male·Age: 18+

Code: NCT07756593·Phase 1

An Observational, Multinational, In Hospital Evaluation of Catheter Utilization Rates in Female Patients Using Indwelling Urinary Catheters and the PureWick™ Flex Female External Catheter Across Europe and the Middle East

for Urinary Incontinence

Sponsor: Becton, Dickinson and Company

Sex: Female·Age: 18+

Code: NCT07798128

Neoadjuvant Intraprostatic OnabotulinumtoxinA Before Radical Prostatectomy for High-Risk Localized Prostate Cancer

for Prostate Cancer

1 site in Houston

Sponsor: The Methodist Hospital Research Institute

Sex: Male·Age: 45 - 80

Code: NCT07796490·Phase 1, Phase 2

Multiparametric Ultrasound for the Diagnosis of Clinically Significant Prostate Cancer

for Prostate Carcinoma

1 site in Philadelphia

Sponsor: Thomas Jefferson University

Sex: Male·Age: 18+

Code: NCT06024772·Phase 3

Identifying the Best Follow up Approach for People Who Have Had Treatment to Cure Newly Diagnosed Prostate Cancer

for Prostate Cancer

Sponsor: Imperial College London

Sex: Male·Age: 18+

Code: NCT07264088

Response With Interim PSMA PET in Metastatic Castration-sensitive Prostate Cancer for Optimization of Adaptive Metastasis-directed Radiotherapy Delivery

for Prostate Cancer

1 site in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: Male·Age: 18+

Code: NCT07674771·EARLY_Phase 1

LuX: Xaluritamig in Participants With Metastatic Castrate Resistant Prostate Cancer and Suboptimal Response to Lutetium 177 Vipivotide Tetraxetan

for Prostate Cancer

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07737925·Phase 2

Researching the Effect of Exercise on Cancer

for Breast Cancer

2 sites incl. Durate

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT04589468

Apply to this trial

Abi/Pred + ADT vs ADT in PSMA-Positive, Conventionally Node-Negative Prostate Cancer

for Prostate Cancer

1 site in Omaha

Sponsor: University of Nebraska

Sex: Male·Age: 30+

Code: NCT07237269·Phase 2

Apply to this trial

Veteran Peer Navigators to Promote Shared Decision Making for PSA Screening

for Prostate Cancer

1 site in New York

Sponsor: VA Office of Research and Development

Sex: Male·Age: 40 - 69·Accepts healthy volunteers

Code: NCT06549036

Characterizing the Genomic Landscape of Prostate Cancer in Native American Populations (NAT-Geno)

for Prostate Cancer

1 site in Oklahoma City

Sponsor: University of Oklahoma

Sex: Male·Age: 18 - 100

Code: NCT06960798

Apply to this trial

Behavioral and/or Mirabegron to Treat Urinary Symptoms in Parkinson Disease

for Overactive Bladder

3 sites incl. Decatur

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT07187466·Phase 4

SCIPI Implementation and Evaluation: A Multi-site Proof-of-Concept Pilot Trial

for Prostate Cancer

1 site in San Antonio

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 18+

Code: NCT07280897

Decision Support Tool to Enhance Germline Genetic Testing for Patients With Prostate Cancer

for Prostate Carcinoma

1 site in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: Male·Age: 18+

Code: NCT07377006

Reduce HEAT: A Randomized Trial of Wearable Thermal Devices for ADT-Induced Hot Flashes

for Prostate Cancer

Sponsor: Dana-Farber Cancer Institute

Sex: Male·Age: 18+

Code: NCT07729150

eMindExCare for Prostate Cancer Patients Undergoing Active Treatment

for Prostate Cancer

Sponsor: The University of Hong Kong

Sex: Male·Age: 18+

Code: NCT07735273

Carboplatin-Enhanced Therapy in BRCA-Mutated or Neuroendocrine-Differentiated Aggressive Metastatic Castration-Sensitive Prostate Cancer

for BRCA-Mutated

Sponsor: Gustave Roussy, Cancer Campus, Grand Paris

Sex: Male·Age: 18 - 80

Code: NCT07591467·Phase 3

Phase II Trial of Zanzalitinib in Patients With Metastatic Castration Resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

1 site in Cleveland

Sponsor: Pedro Barata, MD, MSc

Sex: Male·Age: 18+

Code: NCT07608718·Phase 2

Chemical-Shift-Encoded MRI for Active Bone Marrow Dosimetry in Radiopharmaceutical Therapy

for Metastatic Castration-resistant Prostate Cancer

1 site in Madison

Sponsor: University of Wisconsin, Madison

Sex: Male·Age: 18+

Code: NCT07609225·EARLY_Phase 1

Effects of a Multimodal and Multidimensional Intervention on Urinary Incontinence in Young Nulliparous Female Athletes.

for Urinary Incontinence

Sponsor: Centre Hospitalier Universitaire de Saint Etienne

Sex: Female·Age: 15 - 40·Accepts healthy volunteers

Code: NCT07644273

MRI-based Focal Intraprostatic Simultaneous Integrated Boost (SIB) Intensification With De-escalated Adaptive-risk SBRT for Patients With Low to Intermediate Risk Prostate Cancer

for Prostate Cancer

1 site in Washington D.C.

Sponsor: Georgetown University

Sex: Male·Age: 18+

Code: NCT07644598·Phase 2

Apply to this trial

Rehabilitation and Sex Therapy to Optimize Recovery After Prostate Cancer Treatment

for Prostate Cancer

1 site in Durham

Sponsor: Duke University

Sex: Male·Age: 18+

Code: NCT07685249

MICRO-ultrasound Guided Prostate SBRT

for Prostate Cancer

Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Sex: Male·Age: 18+

Code: NCT07737457

Preoperative Breathing Exercise Training and Postoperative Delirium After Robotic Radical Prostatectomy

for Postoperative Delirium (POD)

Sponsor: ALİ DEMİRTAŞ

Sex: Male·Age: 40+

Code: NCT07766603

Innovative and Cooperative Pathway Integrating Oncogeriatric, Pharmaceutical and Pharmacological Follow-up in Elderly Patients.

for Elderly

Sponsor: Gustave Roussy, Cancer Campus, Grand Paris

Sex: All·Age: 70+

Code: NCT07802847·Phase 4

Safety and Preliminary Diagnostic Performance of [⁶⁴Cu]Cu-RAX301 in Prostate Cancer

for Prostate Cancer

Sponsor: RadAlliance Therapeutics, Inc

Sex: Male·Age: 18+

Code: NCT07765940·Phase 1, Phase 2

proState Cancer Health Education to pRomote Early sreENing Uptake (SCREEN): A Pilot Randomised Control Trial

for Anxiety

Sponsor: Teesside University

Sex: Male·Age: 18 - 70·Accepts healthy volunteers

Code: NCT07800390

A Phase 1 Study of BPX-601 CAR T-Cell Therapy in Adult Participants With Prostate Cancer That Has Returned, is Resistant to Treatment and Has Spread

for Prostate Cancer

2 sites incl. Hackensack

Sponsor: Regeneron Pharmaceuticals

Sex: Male·Age: 18+

Code: NCT07543055·Phase 1

Apply to this trial

Natural History Study of Early Life Exposures in Agriculture (ELEA)

for Prostate Cancer

1 site in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT07328516

Multitargeted Recombinant Ad5 PSA/MUC-1/Brachyury-Based Immunotherapy (TriAdeno) Vaccine With IL-15 Superagonist N-803 in Participants With Clinically Localized Prostate Cancer Undergoing Active Surveillance

for Adenocarcinoma

1 site in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18 - 120

Code: NCT07574541·Phase 2

Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer

for Head and Neck Cancer

1 site in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT07667400·Phase 1, Phase 2

IL-15 Superagonist With or Without Vaccine in Biochemically Recurrent Prostate Cancer After Previous Stereotactic Body Radiation Therapy

for Recurrent Prostate Cancer

1 site in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18 - 120

Code: NCT07686380·Phase 2

Low-Count Quantitative SPECT for Men Treated With Radium-223

for Prostate Cancer

1 site in St Louis

Sponsor: Washington University School of Medicine

Sex: Male·Age: 18+

Code: NCT07221825

Apply to this trial

Clinically Important or Just Statistically Significant? MCID for DVISS and PIN-Q in Children With UI

for Urinary Incontinence

Sponsor: Artvin Coruh University

Sex: All·Age: 5 - 13

Code: NCT07242898

Urine Prostate Screening Integrated With MRI for Early Detection of Prostate Cancer, UPRISE Trial

for Prostate Carcinoma

1 site in Ann Arbor

Sponsor: University of Michigan Rogel Cancer Center

Sex: Male·Age: 50 - 75·Accepts healthy volunteers

Code: NCT07526545

[18F]Fluorthanatrace - Positron Emission Tomography (FTT-PET) and ctDNA to Predict Response to PARP Inhibitor Therapy in Metastatic Prostate Cancer (mPC)

for Metastatic Prostate Cancer

3 sites incl. St Louis

Sponsor: Washington University School of Medicine

Sex: Male·Age: 18+

Code: NCT07723651·Phase 2

Evaluation of the Distribution of 64Cu/68Ga Labeled CM500 in Healthy Volunteers and Patients With Cancer

for Bladder Cancer

3 sites incl. Boston

Sponsor: Lumina Pharmaceuticals Inc

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07781852·EARLY_Phase 1

Comparing the Effect of Two Types of Pelvic Floor Muscle Stimulation Devices to Improve Symptoms of Urinary Incontinence in Women.

for Urinary Incontinence

Sponsor: Espacio Gaspar Clinic

Sex: Female·Age: 18+

Code: NCT07792031

Low Dose Naltrexone (LDN) for Management of Fatigue in Prostate Cancer Patients on Androgen Deprivation Therapy (ADT)

for Metastatic Prostate Cancer

Sponsor: University of Arkansas

Sex: Male·Age: 18+

Code: NCT07224009·Phase 2

Testosterone Replacement Therapy in Hypogonadal Patients With Prostate Cancer Under Active Surveillance

for Prostate Cancer

2 sites in Miami

Sponsor: University of Miami

Sex: Male·Age: 18+

Code: NCT07278362·Phase 4

Prophylactic Antibiotics for Outpatient Urethral Bulking

for Urinary Tract Infections

2 sites in Miami

Sponsor: University of Miami

Sex: Female·Age: 18+

Code: NCT07501065·Phase 4

Apply to this trial

Exercise-induced Steroid Changes in Active Surveillance for Prostate Cancer

for Prostate Cancer

1 site in Miami

Sponsor: University of Miami

Sex: Male·Age: 18 - 80

Code: NCT07518888

Sacituzumab Tirumotecan in Pts w/ NEPC After Progression on Prior Chemotherapy

for Prostate Cancer

1 site in Richmond

Sponsor: Virginia Commonwealth University

Sex: Male·Age: 18+

Code: NCT07639086·Phase 2

Water Vapor Ablation for Grade Group 3 Prostate Cancer

for Prostate Cancer

Sponsor: Francis Medical Inc.

Sex: Male·Age: 50+

Code: NCT07652164

Improving Uroflowmetry Interpretability: Evaluating the Impact of Patient Reminder Systems

for Pelvic Organ Prolapse

1 site in Columbus

Sponsor: Ohio State University

Sex: Female·Age: 18+

Code: NCT07692789

Apply to this trial

Resistance Exercise, IL-7 and Immune Phenotypes in Prostate Cancer

for Prostate Cancer

Sponsor: University of Bath

Sex: Male·Age: 18+

Code: NCT07724080

Effectiveness of Posluma PET Scan for Post-Treatment Monitoring of Prostate Cancer

for Prostate Cancer

Sponsor: Aditya Bagrodia

Sex: Male·Age: 18+

Code: NCT07733908·Phase 2

A Multicenter, Open-label Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of SHR-6914 Injection in Participants With Prostate Cancer

for Prostate Cancer

Sponsor: Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Sex: Male·Age: 18 - 80

Code: NCT07735377·Phase 1

Apply to this trial

Study of Oral MRT-2359 With Apalutamide in Prostate Cancer

for Castration-Resistant Prostate Cancer (CRPC)

14 sites incl. Los Angeles

Sponsor: Monte Rosa Therapeutics, Inc

Sex: Male·Age: 18+

Code: NCT07745361·Phase 2

Apply to this trial

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Men's health clinical trials — common questions

Are men's health clinical trials free to join?

Yes. Participating in a men's health clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a men's health clinical trial?

Each men's health study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a men's health trial near me?

Use the location controls above. We'll show recruiting men's health trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many men's health trials are recruiting right now?

We're currently tracking roughly 526 recruiting men's health trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Men's health trials by city

Los Angeles, CA Boston, MA San Francisco, CA Duarte, CA Chicago, IL La Jolla, CA Miami, FL Cleveland, OH Ann Arbor, MI Birmingham, AL Portland, OR Palo Alto, CA

Conditions in this area

Prostate cancer Metastatic prostate cancer Overactive bladder Urinary incontinence