Prostate cancer Clinical Trials

Recruiting prostate cancer studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat prostate cancer. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting prostate cancer studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting prostate cancer trials

Within

A Phase 1/2 Study of Personalized PSMA Radiopharmaceutical Therapy

for Cancer

Sponsor: CHU de Quebec-Universite Laval

Sex: All·Age: 18+

Code: NCT05896371·Phase 1, Phase 2

A Point of Prostate Cancer Diagnosis Virtual Reality Assistant Intervention in Supporting Newly Diagnosed Black Men

for Prostate Carcinoma

1 site in Jacksonville

Sponsor: Mayo Clinic

Sex: Male·Age: All ages

Code: NCT07126548

Quality and Safety of Real-Time Brachytherapy Treatments: Clinical Implementation of a Multipoint Scintillation Detector for Treatment Monitoring

for Prostate Cancer

Sponsor: CISSS de Chaudière-Appalaches

Sex: All·Age: 18+

Code: NCT07580651

Evaluating Treatment Outcomes Using Darolutamide and Androgen Deprivation Therapy in Patients With Metastatic Hormone-Sensitive Prostate Cancer.

for Prostate Cancer

1 site in Chicago

Sponsor: University of Chicago

Sex: Male·Age: 18+

Code: NCT06660862·Phase 4

Identifying the Best Follow up Approach for People Who Have Had Treatment to Cure Newly Diagnosed Prostate Cancer

for Prostate Cancer

Sponsor: Imperial College London

Sex: Male·Age: 18+

Code: NCT07264088

SCIPI Implementation and Evaluation: A Multi-site Proof-of-Concept Pilot Trial

for Prostate Cancer

1 site in San Antonio

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 18+

Code: NCT07280897

Decision Support Tool to Enhance Germline Genetic Testing for Patients With Prostate Cancer

for Prostate Carcinoma

1 site in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: Male·Age: 18+

Code: NCT07377006

Carboplatin-Enhanced Therapy in BRCA-Mutated or Neuroendocrine-Differentiated Aggressive Metastatic Castration-Sensitive Prostate Cancer

for BRCA-Mutated

Sponsor: Gustave Roussy, Cancer Campus, Grand Paris

Sex: Male·Age: 18 - 80

Code: NCT07591467·Phase 3

MRI-based Focal Intraprostatic Simultaneous Integrated Boost (SIB) Intensification With De-escalated Adaptive-risk SBRT for Patients With Low to Intermediate Risk Prostate Cancer

for Prostate Cancer

1 site in Washington D.C.

Sponsor: Georgetown University

Sex: Male·Age: 18+

Code: NCT07644598·Phase 2

Low-Count Quantitative SPECT for Men Treated With Radium-223

for Prostate Cancer

1 site in St Louis

Sponsor: Washington University School of Medicine

Sex: Male·Age: 18+

Code: NCT07221825

Apply to this trial

Urine Prostate Screening Integrated With MRI for Early Detection of Prostate Cancer, UPRISE Trial

for Prostate Carcinoma

1 site in Ann Arbor

Sponsor: University of Michigan Rogel Cancer Center

Sex: Male·Age: 50 - 75·Accepts healthy volunteers

Code: NCT07526545

Testosterone Replacement Therapy in Hypogonadal Patients With Prostate Cancer Under Active Surveillance

for Prostate Cancer

2 sites in Miami

Sponsor: University of Miami

Sex: Male·Age: 18+

Code: NCT07278362·Phase 4

Strategic Endocrine Therapy and Targeted Radiotherapy for Prostate Cancer

for Prostate Adenocarcinoma

1 site in La Jolla

Sponsor: University of California, San Diego

Sex: Male·Age: 18+

Code: NCT07364071·Phase 2

Exercise-induced Steroid Changes in Active Surveillance for Prostate Cancer

for Prostate Cancer

1 site in Miami

Sponsor: University of Miami

Sex: Male·Age: 18 - 80

Code: NCT07518888

Sacituzumab Tirumotecan in Pts w/ NEPC After Progression on Prior Chemotherapy

for Prostate Cancer

1 site in Richmond

Sponsor: Virginia Commonwealth University

Sex: Male·Age: 18+

Code: NCT07639086·Phase 2

Veteran Peer Navigators to Promote Shared Decision Making for PSA Screening

for Prostate Cancer

1 site in New York

Sponsor: VA Office of Research and Development

Sex: Male·Age: 40 - 69·Accepts healthy volunteers

Code: NCT06549036

Comparing Acupuncture vs. Sham Acupuncture for the Management of Hot Flashes in Prostate Cancer Patients Receiving Hormone Therapy

for Accupuncture

1 site in Lexington

Sponsor: University of Kentucky

Sex: All·Age: 18 - 99

Code: NCT07594002

dMD-002 Pilot Study in Patients With Cavernous Nerve Injury Following Radical Prostatectomy

for Prostate Cancer

1 site in New York

Sponsor: Mochida Medical USA, Inc.

Sex: Male·Age: 40 - 74

Code: NCT07564102·Phase 1, Phase 2

A Phase 2 Trial of 61Cu-NU101 PET/CT Compared Against Current Standard-of-care 18F-piflufolastat (Pylarify®) PET/CT.

for Prostate Cancer

2 sites incl. Newport Beach

Sponsor: Hoag Memorial Hospital Presbyterian

Sex: Male·Age: 18+

Code: NCT07635524·Phase 2

Sexual Health Communication Skills Training Intervention for Patients With Prostate Cancer

for Prostate Cancer

1 site in New York

Sponsor: NYU Langone Health

Sex: Male·Age: 18+

Code: NCT07655557

Effects of Direct Artery Injection on Prostate Cancer Drug Delivery and Tumor Uptake: Imaging-Based Prediction of Treatment Effectiveness

for Prostate Cancer

Sponsor: Lithuanian University of Health Sciences

Sex: Male·Age: 18+

Code: NCT07656337

Targeted Biopsy, Rapid Pathology, and Immediate Surgery in USTC High-Risk Prostate Cancer: A Prospective Multicenter Study

for Prostate Cancer

Sponsor: Anhui Provincial Hospital

Sex: Male·Age: 18+

Code: NCT07709338

Radioactive Counts From PSMA PET/CT-Targeted Biopsy Specimens for Real-time Diagnosis of Prostate Cancer: A Prospective Study

for Prostate Cancer

Sponsor: Peking University First Hospital

Sex: Male·Age: 18 - 80

Code: NCT07709403

Multiparametric Ultrasound for the Diagnosis of Clinically Significant Prostate Cancer

for Prostate Carcinoma

1 site in Philadelphia

Sponsor: Thomas Jefferson University

Sex: Male·Age: 18+

Code: NCT06024772·Phase 3

Clinical Trial to Observe the Effects of Tamoxifen on Testosterone Recovery in Medically Castrated Prostate Cancer Patients

for Hypogonadism

Sponsor: University Health Network, Toronto

Sex: Male·Age: 18+

Code: NCT07535905·Phase 2

A Study of [225Ac]Ac-AKY-2519 in Patients With Metastatic Castration-Resistant Prostate Cancer

for Castration Resistant Metastatic Prostate Cancer

4 sites incl. Irvine

Sponsor: Aktis Oncology, Inc.

Sex: Male·Age: 18+

Code: NCT07581184·Phase 1

Apply to this trial

Prostate Specific Membrane Antigen (PSMA) Imaging for Detection of Residual and Metastatic Prostate Cancer

for Prostate Cancer

1 site in St Louis

Sponsor: Washington University School of Medicine

Sex: Male·Age: 18+

Code: NCT07593079·Phase 2

Patients With Metastasized Prostate Cancer Whose Prostate-specific Antigen-level (PSA) Remains >0,2 ng/ml After Six Months of Dual Antihormonal Therapy Will Receive Radiotherapy to the Prostate and Radiotherapy to Refractory Metastases

for Prostate Cancer

Sponsor: University Hospital Tuebingen

Sex: Male·Age: 18 - 85

Code: NCT07644754

Water Vapor Ablation for Grade Group 3 Prostate Cancer

for Prostate Cancer

Sponsor: Francis Medical Inc.

Sex: Male·Age: 50+

Code: NCT07652164

Rehabilitation and Sex Therapy to Optimize Recovery After Prostate Cancer Treatment

for Prostate Cancer

1 site in Durham

Sponsor: Duke University

Sex: Male·Age: 18+

Code: NCT07685249

Infrared Fluorescence Staining Versus Frozen Section for Prostate Cancer Surgery

for Prostate Cancer

Sponsor: Xiangya Hospital of Central South University

Sex: Male·Age: 18+

Code: NCT07690462

A Clinical Study of HRS-7525 Tablets in Patients With Advanced Prostate Cancer

for Prostate Cancer

Sponsor: Jiangsu HengRui Medicine Co., Ltd.

Sex: Male·Age: 18 - 80

Code: NCT07711184·Phase 1

Natural History Study of Early Life Exposures in Agriculture (ELEA)

for Prostate Cancer

1 site in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT07328516

Multitargeted Recombinant Ad5 PSA/MUC-1/Brachyury-Based Immunotherapy (TriAdeno) Vaccine With IL-15 Superagonist N-803 in Participants With Clinically Localized Prostate Cancer Undergoing Active Surveillance

for Adenocarcinoma

1 site in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18 - 120

Code: NCT07574541·Phase 2

Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer

for Head and Neck Cancer

1 site in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT07667400·Phase 1, Phase 2

IL-15 Superagonist With or Without Vaccine in Biochemically Recurrent Prostate Cancer After Previous Stereotactic Body Radiation Therapy

for Recurrent Prostate Cancer

1 site in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18 - 120

Code: NCT07686380·Phase 2

Whole Versus Partial Gland Boost During Prostate SBRT

for Prostate Cancer

1 site in Omaha

Sponsor: University of Nebraska

Sex: Male·Age: 19+

Code: NCT07574489·Phase 2, Phase 3

QLF4113 in Participants With Metastatic Prostate Cancer

for Prostate Cancer

Sponsor: Qilu Pharmaceutical Co., Ltd.

Sex: Male·Age: 18+

Code: NCT07636707·Phase 1

Transperineal Micro-ultrasound for the Detection of Prostate Cancer During Biopsy

for Prostate Carcinoma

1 site in Buffalo

Sponsor: Roswell Park Cancer Institute

Sex: Male·Age: 18+

Code: NCT07075705

Response With Interim PSMA PET in Metastatic Castration-sensitive Prostate Cancer for Optimization of Adaptive Metastasis-directed Radiotherapy Delivery

for Castrate Sensitive Prostate Cancer

1 site in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: Male·Age: 18+

Code: NCT07674771·EARLY_Phase 1

Predictors of BCR After RARP for Localized Prostate Cancer: A Retrospective Analysis

for Prostate Cancer

Sponsor: First Affiliated Hospital of Fujian Medical University

Sex: Male·Age: All ages

Code: NCT07682584

MRI-DTI Assessment of Urethral Internal Sphincter Ring and Prostate Base Morphology

for Urethral Internal Sphincter Morphology

Sponsor: Jiangsu Taizhou People's Hospital

Sex: Male·Age: 15 - 90

Code: NCT07694752

Apply to this trial

SL-28 for Advanced Solid Tumours

for Head & Neck Cancer

Sponsor: Second Life Therapeutics

Sex: All·Age: 18+

Code: NCT07341737·Phase 1, Phase 2

Apply to this trial

Elective Adaptive Radiation With SBRT for Improved DurabilitY of Response

for Prostate Adenocarcinoma

Sponsor: University Health Network, Toronto

Sex: Male·Age: 18+

Code: NCT06831032

Apply to this trial

Stem Cells for Erectile Dysfunction Post RALP

for Erectile Dysfunction

1 site in Houston

Sponsor: The Methodist Hospital Research Institute

Sex: Male·Age: 40 - 70

Code: NCT07048314·Phase 1, Phase 2

Apply to this trial

A Phase 1 Study of BPX-601 CAR T-Cell Therapy in Adult Participants With Prostate Cancer That Has Returned, is Resistant to Treatment and Has Spread

for Prostate Cancer

1 site in Hackensack

Sponsor: Regeneron Pharmaceuticals

Sex: Male·Age: 18+

Code: NCT07543055·Phase 1

Apply to this trial

A Single-Arm, Blinded, Fluorescent PSMA Histopathology Trial of AS1986NS

for Prostate Cancer

2 sites incl. Miami

Sponsor: Antelope Surgical Solutions, Inc

Sex: Male·Age: 18 - 90

Code: NCT06906471·Phase 1, Phase 2

Apply to this trial

Pacritinib in Participants With Metastatic Castrate-Resistant Prostate Cancer That Progressed on or After Prior Treatment With Androgen Receptor Signaling Inhibitors

for Prostate Cancer

1 site in Milwaukee

Sponsor: Medical College of Wisconsin

Sex: Male·Age: 18+

Code: NCT07226713·Phase 2

Terbium 161 PSMA in Lutetium-177 PSMA Naive Patients

for Prostate Cancer

Sponsor: Ankara University

Sex: Male·Age: 18+

Code: NCT07441837·Phase 2

Stockholm3 Test Validation in Men on Active Surveillance in Switzerland (CHAS3 Trial)

for Prostate Cancer

Sponsor: Insel Gruppe AG, University Hospital Bern

Sex: Male·Age: All ages

Code: NCT07478536

Evaluation of a Prostate-Targeted PET Imaging System (P-PET) for Detecting Prostate Cancer

for Prostate Cancer

Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Sex: Male·Age: All ages

Code: NCT07510906

A Trial on Fezolinetant for Vasomotor Symptoms in Men Receiving Androgen Deprivation Therapy (ADT)

for Vasomotor Symptoms

Sponsor: Chinese University of Hong Kong

Sex: Male·Age: 18+

Code: NCT07568236·Phase 2

Perspectives About Online Information

for Prostate Cancer

1 site in New York

Sponsor: NYU Langone Health

Sex: All·Age: 40+·Accepts healthy volunteers

Code: NCT07631858

Study of PSMA-targeted Therapy and Androgen Receptor Suppression in Low-volume Metastatic ProstatE Cancer: SPARKLE Trial

for Recurrent Prostate Adenocarcinoma

1 site in Rochester

Sponsor: Mayo Clinic

Sex: Male·Age: 18+

Code: NCT07650240·Phase 2

A Study of [177Lu]Lu-A9-0631 and [225Ac]Ac-A9-0642 With [68Ga]Ga-A9-6217 or [177Lu]Lu-A9-0631 Imaging in GRPR+ Solid Tumors

for Breast Cancer

Sponsor: Alpha-9 Oncology USA Inc.

Sex: All·Age: 18+

Code: NCT07661641·Phase 1

Apply to this trial

COQ10 and Vitamin E for Off-Target Radiation Toxicity

for Prostate Cancer

1 site in Omaha

Sponsor: University of Nebraska

Sex: All·Age: 19+

Code: NCT07668284·Phase 1, Phase 2

177Lu-PSMA-617 Combined With Darolutamide in Neoadjuvant Treatment of High-risk Localized Prostate Cancer: a Prospective, Single-arm, Multi-center Clinical Trial

for Prostate Cancer

Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Sex: Male·Age: 18 - 75

Code: NCT07677566·Phase 4

High-resolution Intra-operative PSMA PET-CT in Prostate Cancer

for Prostate Cancer

Sponsor: IRCCS San Raffaele

Sex: Male·Age: 18 - 80

Code: NCT06298838

Folate Study in Men With Advanced Prostate Cancer

for Prostate Cancer

1 site in La Jolla

Sponsor: University of California, San Diego

Sex: Male·Age: 18+

Code: NCT06536374·Phase 2

Study to Assess the Feasibility of Stopping Prostate Cancer Treatment Early in Elderly Patients

for Elderly

2 sites in Chicago

Sponsor: University of Chicago

Sex: Male·Age: 70+

Code: NCT06824818

Apply to this trial

Prostate cancer clinical trials — common questions

Are prostate cancer clinical trials free to join?

Yes. Participating in a prostate cancer clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a prostate cancer clinical trial?

Each prostate cancer study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a prostate cancer trial near me?

Use the location controls above. We'll show recruiting prostate cancer trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many prostate cancer trials are recruiting right now?

We're currently tracking roughly 407 recruiting prostate cancer trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Prostate cancer trials by city

Los Angeles, CA Boston, MA San Francisco, CA Chicago, IL Duarte, CA Miami, FL La Jolla, CA Ann Arbor, MI Cleveland, OH Jacksonville, FL Birmingham, AL Portland, OR

Related specialties

Oncology Prostate oncology Men's health Urology