A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine

Part of paid clinical trials in Birmingham, Alabama.

Sponsor
Kallyope Inc.
Study ID
NCT07645924
Phase
PHASE3
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • Elismetrep — DRUG
    Administered orally
  • Placebo — DRUG
    Administered orally

Study Details

This is a double-blind, randomized, multicenter, outpatient evaluation of the efficacy, safety, and tolerability of elismetrep, as compared with placebo, in the acute treatment of migraine.

Key Dates

First listed
Jun 12, 2026
Start date
Jul 31, 2026
Status verified
Jul 2026
Primary completion
Feb 28, 2027
Completion
Feb 28, 2027

Study Design

Enrollment
1,800 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Elismetrep 10 mg
  • Experimental: Elismetrep 20 mg
  • Placebo Comparator: Placebo

Primary Outcome Measure

Pain freedom at 2 hours post-dose [ Time Frame: Two hours post-dose ]

Central Contacts

Locations (114)

FacilityCityStateZIPSite coordinators
Central Research Associates, LLC (CRA) dba Flourish ResearchBirminghamAlabama35205
(205) 327-1077
AMR MobileMobileAlabama36608
(251) 901-2127
TrialSphereChandlerArizona85286
(623) 267-8314
Arkansas Clinical ResearchLittle RockArkansas72205
(501) 480-5088
Axiom Research, LLCColtonCalifornia92324
(909) 824-2325
ProScience Research GroupCulver CityCalifornia90230
(424) 227-8127
Leading Edge Research LA, LLCEncinoCalifornia91316
(818) 578-4555
Axiom Research, Orange CountyIrvineCalifornia92604
(909) 824-2325
Clinical Research InstituteLos AngelesCalifornia90048
(323) 879-9999
Downtown L.A. Research Center, Inc.Los AngelesCalifornia90017
(213) 261-3680
M3 Wake Research - Mission Mental Health (WR-MMH)Mission ViejoCalifornia92691
(949) 752-7910
Excell ResearchOceansideCalifornia92056
(760) 758-2222
Empire Clinical ResearchPomonaCalifornia91767
(909) 981-5321
The Neurology GroupPomonaCalifornia91767
(909) 982-2719
Artemis Institute for Clinical ResearchRiversideCalifornia92503
(855) 367-8834
Acclaim Clinical ResearchSan DiegoCalifornia92120
(855) 367-8834
CenExel Sherman Oaks CA (California Neuroscience Research)Sherman OaksCalifornia91403
(818) 990-2671
Encompass Clinical ResearchSpring ValleyCalifornia91978
(619) 660-9068
Diablo Clinical ResearchWalnut CreekCalifornia94598
(925) 930-7267
Sunwise Clinical ResearchWalnut CreekCalifornia94596
(925) 298-5147
Kinetic Clinical ResearchWest CovinaCalifornia91790
(657) 230-7120
Focus Clinical ResearchWest HillsCalifornia91307
(818) 253-8966
IMMUNOe Research CentersCentennialColorado80112
(303) 771-9000
MCB Clinical Research CentersColorado SpringsColorado80910
(719) 634-6576
Advanced Neurosciences ResearchFort CollinsColorado80528
(970) 226-6111
Chase Medical Research, LLCWaterburyConnecticut06708
(203) 419-4404
DelRicht ResearchAtlantaGeorgia30329
(770) 417-4454
Drug Studies AmericaMariettaGeorgia30060
(678) 581-5252
Sleep Care Research Institute d/b/a Clinical Research Atlanta-StockbridgeStockbridgeGeorgia30281
(770) 626-0177
Cedar Crosse Research CenterChicagoIllinois60607
(312) 431-6780
Chicago Headache Center & Research InstituteChicagoIllinois60657
(773) 935-1000
Healthcare Research Network II, LLCFlossmoorIllinois60477
(708) 388-2245
Chicago Headache Center & Research InstituteNapervilleIllinois60563
(415) 397-0700
Integrated Clinical Trials SolutionWest Des MoinesIowa50265
(515) 223-2300
Clinical Associates Midwest, LLCOverland ParkKansas66214
(913) 359-5699
Collective Medical ResearchOverland ParkKansas66212
(913) 381-7180
Heartland Research Associates, LLC - An AMR CompanyWichitaKansas67207
(316) 689-6635
Physicians to Children & Adolescents, PSC (Kentucky Pediatric / Adult Research)BardstownKentucky40004
(502) 349-1569
AMR Clinical - LexingtonLexingtonKentucky40509
(859) 264-8999
CTI Clinical Research CenterLexingtonKentucky45212
(513) 721-3868
Monroe Biomedical Research (former L-MARC Research Center)LouisvilleKentucky40213
(502) 305-1010
Crescent City Headache & Neurology CenterChalmetteLouisiana70043
(504) 418-6040
DelRicht ResearchNew OrleansLouisiana70115
(504) 336-2667
Headlands Research - PharmaSitePikesvilleMaryland21208
(410) 602-1440
Boston Clinical Trials - AlcanzaBostonMassachusetts02131
(843) 856-3784
MedVadis Research Corporation, LLCWalthamMassachusetts02451
(781) 373-2940
Michigan Headache Pain & Neurological InstituteAnn ArborMichigan48104
(734) 677-6000
Clinical Research InstituteMinneapolisMinnesota55402
(612) 333-2200
DelRicht ResearchGulfportMississippi39503
(228) 588-8268
Proven EndpointsRidgelandMississippi39157
(601) 790-1811
StudyMetrix ResearchCity of Saint PetersMissouri63303
(636) 387-5100
Healthcare Research NetworkHazelwoodMissouri63042
(314) 972-9600
AMR Clinical - Kansas CityKansas CityMissouri64114
(816) 643-4153
Clinvest Headlands LLCSpringfieldMissouri65807
(417) 883-7889
Sundance Clinical ResearchSt LouisMissouri63141
(314) 567-3377
AMR Clinical - Las VegasLas VegasNevada89119
(702) 529-0153
Excel Clinical ResearchLas VegasNevada89109
(702) 680-1500
IMA Clinical Research - Las VegasLas VegasNevada89102
(702) 527-7401
Redbird ResearchLas VegasNevada89119
(702) 577-2000
Wake Research Las Vegas RainbowLas VegasNevada89118
(702) 893-8968
Las Vegas Clinical TrialsNorth Las VegasNevada89030
(702) 637-3223
Advanced Research Institute - RenoRenoNevada89511
(775) 502-1616
Albuquerque Clinical TrialsAlbuquerqueNew Mexico87102
(505) 224-7407
Dent Neuro Institute, BuffaloAmherstNew York14226
(716) 250-2017
SPRI Clinical Trials, LLCBrooklynNew York11235
(646) 747-4060
True North NeurologyCommackNew York11725
(631) 364-9119
Central New York Clinical ResearchManliusNew York13104
(315) 682-3263
Fieve Clinical Research, IncNew YorkNew York10017
(212) 772-3570
Rochester Clinical ResearchRochesterNew York14609
(585) 288-0890
Upstate Clinical Research AssociatesWilliamsvilleNew York14221
(716) 626-6320
OnSite Clinical SolutionsCharlotteNorth Carolina28277
(800) 785-3150
Guildford Neurologic Research Partners, LLCGreensboroNorth Carolina27405
(336) 516-9103
Headache Wellness CenterGreensboroNorth Carolina27405
(336) 574-8000
Eximia Research - NC, LLCRaleighNorth Carolina27607
(919) 800-5154
Carolina Research Center, IncShelbyNorth Carolina28150
(704) 487-5228
Hometown ResearchColumbusOhio43228
(614) 362-3980
Hometown ResearchMilfordOhio45150
(513) 831-5900
CincyScienceWest ChesterOhio45069
(513) 646-4864
OK Clinical Research, LLCEdmondOklahoma73034
(405) 285-6811
Hightower ClinicalOklahoma CityOklahoma73102
(405) 479-8331
DelRicht ResearchTulsaOklahoma74133
(918) 932-2276
Tekton Research, Inc.YukonOklahoma73099
(405) 281-3433
Advanced Research Institute - PortlandPortlandOregon97223
(503) 610-0033
Summit Research NetworkPortlandOregon97210
(855) 367-8834
Lehigh Center for Clinical ResearchAllentownPennsylvania18103
(818) 578-4555
Clinical Research PhiladelphiaPhiladelphiaPennsylvania19114
(215) 676-6696
Preferred Primary Care Physicians, Inc.PittsburghPennsylvania15236
(412) 650-6155
Frontier Clinical Research, LLCScottdalePennsylvania15683
(724) 220-5281
Frontier Clinical Research, LLCSmithfieldPennsylvania15478
(724) 569-8036
Coastal Carolina Research CenterNorth CharlestonSouth Carolina29405
(843) 856-3784
WR-ClinSearch, LLCChattanoogaTennessee37421
(423) 698-4584
Access Clinical Trials, IncNashvilleTennessee37203
(615) 320-6076
Clinical Research Associates, Inc.NashvilleTennessee37203
(615) 329-0197
FutureSearch Trials of NeurologyAustinTexas78731
(512) 380-9925
Tekton ResearchAustinTexas78745
(512) 859-3834
APD Clinical ResearchCypressTexas77372
(281) 315-4986
Horizon Clinical Research and Gill NeuroscienceCypressTexas77429
(949) 491-0710
FutureSearch Trials of Dallas, LPDallasTexas75251
(214) 361-7700
DM Clinical ResearchHoustonTexas77081
(346) 550-9559
Victorium Clinical ResearchHoustonTexas77024
(832) 203-7026
GMG Clinical Research, LLC dba Radiance Clinical ResearchLampasasTexas76550
(512) 556-4130
Aim Trials, LLCPlanoTexas75093
(214) 856-2778
Clinpoint TrialsWaxahachieTexas75165
(972) 937-1640
Pantheon Clinical ResearchBountifulUtah84010
(385) 281-0550
J. Lewis Research, Inc. / Foothill Family Clinic DraperDraperUtah84020
(801) 365-1032
Advanced Research InstituteOgdenUtah84405
(801) 409-2040
Granger Medical ClinicRivertonUtah84096
(801) 302-1769
J. Lewis Research, Inc. / Foothill Family ClinicSalt Lake CityUtah84109
(801) 486-3021
J. Lewis Research, Inc. / Foothill Family ClinicSalt Lake CityUtah84121
(801) 365-1032
Health Research of Hampton Roads, Inc. (HRHR)Newport NewsVirginia23606
(757) 591-8100
AMR Clinical - NorfolkNorfolkVirginia23502
(757) 614-1001
Seattle Clinical Research CenterSeattleWashington98104
(206) 522-3330
Frontier Clinical ResearchMorgantownWest Virginia26505
(304) 241-1648
Clinical Investigation Specialists, Inc.KenoshaWisconsin53144
(847) 406-8080

Find similar trials in Birmingham, AL

Nationwide
Migraine trialsNeurology trials
By condition
Migraine
By specialty
Neurology
By research site
Central Research Associates, LLC (CRA) dba Flourish Research· Birmingham, ALAMR Mobile· Mobile, ALTrialSphere· Chandler, AZArkansas Clinical Research· Little Rock, ARAxiom Research, LLC· Colton, CAProScience Research Group· Culver City, CA

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