Intraarticular Injection of Botox and Hyaluronic Acid in Knee Osteoarthritis

Sponsor
Tanta University
Study ID
NCT07666347
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
50 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Hyaluronic acid — DRUG
    Patients will be given intra-articular injection of 2 ml of hyaluronic acid into the joint space three times weekly.
  • Botulinum toxin type A — DRUG
    Patients will be given intra-articular injection of 100 units of Botulinum toxin type A, diluted with 5 ml of normal saline three times weekly.

Study Details

This study aims to compare the efficacy of intra-articular injection of Botulinum toxin and hyaluronic acid on pain in knee osteoarthritis.

Key Dates

First listed
Jun 24, 2026
Start date
Jun 24, 2026
Status verified
Jun 2026
Primary completion
Dec 1, 2026
Completion
Dec 1, 2026

Study Design

Enrollment
50 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Group HA
    Patients will be given intra-articular injection of 2 ml of hyaluronic acid into the joint space three times weekly.
  • Experimental: Group BTX
    Patients will be given intra-articular injection of 100 units of Botulinum toxin type A, diluted with 5 ml of normal saline three times weekly.

Primary Outcome Measure

Degree of pain [ Time Frame: 3 months after the interventions ]

Central Contacts

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