Circulatory Exercise After Total Knee Replacement

Sponsor
Assiut University
Study ID
NCT07688642
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • standard postoperative TKR rehabilitation — OTHER
    Participants will receive standard postoperative total knee replacement rehabilitation according to the local hospital protocol, including early mobilization, ROM exercises, quadriceps activation, ambulation training, and standard pain/edema management as clinically indicated.
  • Standard Rehabilitation Plus Circulatory Exercise — OTHER
    Participants will receive standard postoperative rehabilitation plus a circulatory exercise protocol including supine leg elevation with ankle pump and knee extension, and seated knee extension with alternating ankle dorsiflexion. The exercise will be performed at approximately 15 cycles/minute, 10 sets of 1 minute, 60 seconds rest between sets, twice daily for 14 postoperative days.

Study Details

Total knee replacement is commonly associated with early postoperative inflammation, edema, pain, and reduced mobility. This randomized controlled trial will evaluate whether adding a simple circulatory exercise program to standard postoperative rehabilitation reduces early limb edema and inflammatory response after unilateral primary total knee replacement. Participants will be randomized to standard rehabilitation alone or standard rehabilitation plus seated and supine knee-extension exercises with alternating ankle dorsiflexion. The primary endpoint is change in limb edema measured by standardized limb circumference at postoperative day 14.

Key Dates

First listed
Jul 7, 2026
Start date
Jun 16, 2026
Status verified
Mar 2026
Primary completion
May 31, 2027
Completion
May 16, 2027

Study Design

Enrollment
68 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: standard postoperative TKR rehabilitation (hospital protocol)
  • Experimental: Circulatory Exercise Protocol (in addition to standard rehab)

Primary Outcome Measure

Difference in postoperative lower-limb edema between the operated and contralateral limbs measured by standardized limb circumference (cm) [ Time Frame: Baseline/preoperative to postoperative day 14 ]

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