NASA Exercise Prebreathe Study

Conditions

• Decompression Sickness

Eligibility Criteria

Sex

ALL

Age

30 Years - 60 Years

Healthy Volunteers

Accepted

Interventions

• Oxygen Prebreathe and Hypobaric Exposure — PROCEDURE
  Prebreathe 100% oxygen followed by simulated spacewalk conditions in hypobaric chamber with exercise protocols.

Study Details

This study evaluates oxygen prebreathe protocols and exercise conditions to reduce risk of decompression sickness during simulated extravehicular activity. Healthy adult volunteers will undergo oxygen prebreathe followed by hypobaric chamber exposure with monitoring for symptoms and ultrasound detection of bubbles.

Key Dates

First listed

Jul 14, 2026

Start date

Aug 13, 2026

Status verified

Sep 2026

Primary completion

Feb 27, 2027

Completion

Feb 27, 2027

Study Design

Enrollment

30 participants (estimated)

Allocation

NA

Intervention model

SINGLE_GROUP

Primary purpose

PREVENTION

Arms

• Experimental: Single Arm
  Participants undergo oxygen prebreathe followed by hypobaric chamber exposure with exercise and monitoring.

Primary Outcome Measure

Number of participants with Decompression Sickness [ Time Frame: Up to 6 months ]

Locations (1)

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