Low Dose Radiotherapy for Osteoarthritis

Conditions

• Osteoarthitis

Eligibility Criteria

Sex

ALL

Age

18 Years - N/A

Healthy Volunteers

Not accepted

Interventions

• Low Dose Radiation Therapy — RADIATION
  Participants will complete study intervention which consists of the BPI-SF, PROMIS Global v1.2, UEFI (for those with joint pain of the upper extremity) and/or LEFS (for those joint pain of the lower extremity) at baseline, 3-month and 1-year follow-up following 1 or 2 courses of standard of care LDRT.

Study Details

This single institution, multi-site, single arm prospective study will enroll patients with a history of OA and assess changes in pain and function after treatment with LDRT as measured by patient-reported outcomes.

Key Dates

First listed

Jul 20, 2026

Start date

Jun 24, 2026

Status verified

Jul 2026

Primary completion

Jun 30, 2029

Completion

Jun 30, 2029

Study Design

Enrollment

113 participants (estimated)

Allocation

NA

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Arms

• Other: Single
  Participants will complete study intervention which consists of the BPI-SF, PROMIS Global v1.2, UEFI (for those with joint pain of the upper extremity) and/or LEFS (for those joint pain of the lower extremity) at baseline, 3-month and 1-year follow-up following 1 or 2 courses of standard of care LDRT.

Primary Outcome Measure

To measure the percentage of subjects who experience a best response of 1 point or more on BPI-SF [ Time Frame: Within 1 year ]

Central Contacts

• Marlowe Estioko, BS, MS
  267-343-6483
  [email protected]
• Sonya George, BS
  267-760-7636
  [email protected]

Locations (2)

Find similar trials in Philadelphia, PA

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  PHASE2 · Not Yet Recruiting · University of Tennessee · Memphis, Tennessee