Behavioral Interventions Combining AI/ML and Personalized Medicine to Reduce Cardiovascular Risk - Randomized Controlled Trial

Part of paid clinical trials in La Jolla, California.

Sponsor: National Bureau of Economic Research, Inc.
Study ID: NCT07725250
Status: Recruiting

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Conditions

Hypertension

Eligibility Criteria

Sex: ALL
Age: 18 Years - N/A
Healthy Volunteers: Not accepted

Interventions

Digital heath tool — OTHER
Digital health tool of patient-tailored lifestyle recommendations for blood pressure maintenance. Current "simplified" remote patient monitoring program referred to as "P1000." Requires daily blood pressure readings only.
Low-intensity recommendation — OTHER
AI-enhanced lifestyle and health recommendations provided weekly. This requires blood pressure readings, as well as passive readings, (e.g. sleep, movement), and a daily questionnaire.
High-intensity recommendation — OTHER
AI-enhanced lifestyle and health recommendations provided weekly, plus daily reminders. This requires blood pressure readings, as well as passive readings, (e.g. sleep, movement), and a daily questionnaire.

Study Details

This study evaluates a new digital health program that uses artificial intelligence (AI) to help patients lower their blood pressure through personalized lifestyle recommendations. The program collects information about patients' daily habits and blood pressure readings, then uses AI to suggest lifestyle changes that may work best for each person. The study will measure how well this program works across different groups of patients and aims to improve the program design to make it more effective and easier to use. The program will be offered to diverse patients at UC San Diego Health, including people of different ages, genders, races/ethnicities, and economic backgrounds, as part of their regular healthcare services.

Key Dates

First listed: Jul 24, 2026
Start date: Apr 10, 2026
Status verified: Jul 2026
Primary completion: Apr 30, 2027
Completion: Apr 30, 2027

Study Design

Enrollment: 3,000 participants (estimated)
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Arms

Experimental: RCT Arm A: Digital health tool
Participants in this arm will receive the Digital Health Tool intervention.
Experimental: RCT Arm B.1: Digital health tool + low-intensity recommendations
Participants in this arm will receive the Digital Health Tool and Low-Intensity Recommendation interventions.
Experimental: RCT Arm B.2: Digital health tool + high-intensity recommendations
Participants in this arm will receive the Digital Health Tool and High-Intensity Recommendation interventions.