This Study Examines Whether Personality Traits Influence the Frequency or Severity of Ocular Adverse Effects Reported by Patients Using Glaucoma Medications. The Findings May Identify Patients at Greater Risk of Intolerance and Support More Personalized Treatment and Counselling.

Sponsor
McGill University Health Centre/Research Institute of the McGill University Health Centre
Study ID
NCT07739784
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • No Interventions — OTHER
    There is no intervention

Study Details

The goal of this observational study is to learn whether personality traits are related to eye side effects from glaucoma medications in adults who currently use or previously used these medications. The main questions this study aims to answer are: Are certain personality traits associated with the occurrence or severity of eye side effects from glaucoma medications? Do personality traits differ between people who experience these side effects and those who do not? Participants will complete a questionnaire that measures five personality traits: openness, conscientiousness, extraversion, agreeableness, and neuroticism. They will also provide basic demographic information. The researchers will review participants' medical records to collect information about their glaucoma medications and any related eye side effects, including the type and frequency of side effects and whether treatment was changed because of them. Participation involves one session lasting approximately 30 minutes. Questionnaires may be completed securely online or in person at the clinic. The study will include approximately 352 adults. No treatment will be assigned or changed as part of this study.

Key Dates

First listed
Jul 31, 2026
Start date
Feb 25, 2026
Status verified
Jul 2026
Primary completion
Jul 1, 2027
Completion
Aug 1, 2027

Study Design

Enrollment
352 participants (estimated)

Arms

  • Arm: Case
    Participants with at least one documented ocular adverse effect from a glaucoma medication that resulted in discontinuation of the medication.
  • Arm: Control
    Participants without a documented significant ocular adverse effect resulting in medication discontinuation.

Primary Outcome Measure

Difference in Five-Factor Model neuroticism scores between participants with and without significant ocular adverse reactions [ Time Frame: Assessed once during the single study session, lasting approximately 30 minutes. ]

Central Contacts

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