A Study of JNJ-98768111 in Participants With Advanced Prostate Cancer

Part of paid clinical trials in Sarasota, Florida.

Sponsor
Janssen Research & Development, LLC
Study ID
NCT07746713
Phase
PHASE1
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
MALE
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • JNJ-98768111 — DRUG
    JNJ-98768111 will be administered intravenously.

Study Details

The purpose of Part 1 of this study is to find out how safe JNJ-98768111 is and the most suitable dose (recommended phase 2 dose \[RP2D\]) regimen(s) of JNJ-98768111. The purpose of Part 2 of this study is to find out how safe JNJ-98768111 is at the RP2D regimen(s) in participants with advanced prostate cancer (cancer of the prostate, a male reproductive gland found below the bladder, which has spread extensively to other parts of the body).

Key Dates

First listed
Aug 5, 2026
Start date
Aug 5, 2026
Status verified
Aug 2026
Primary completion
Mar 16, 2029
Completion
Mar 16, 2029

Study Design

Enrollment
100 participants (estimated)
Allocation
NA
Intervention model
SEQUENTIAL
Primary purpose
TREATMENT

Arms

  • Experimental: JNJ-98768111
    Participants in Part 1 of the study will receive escalating doses of JNJ-98768111 to identify the putative recommended phase 2 dose (pRP2D) regimen(s). Participants in Part 2 of the study will receive JNJ-98768111 at the pRP2D regimen(s) determined in Part 1.

Primary Outcome Measure

Number of Participants with Adverse Events (AEs) [ Time Frame: Up to approximately 2 years 7 months ]

Central Contacts

Locations (3)

FacilityCityStateZIPSite coordinators
Florida Cancer Specialists & Research InstituteSarasotaFlorida34232-
Start MidwestGrand RapidsMichigan49546-
START Mountain RegionWest Valley CityUtah84119-

Find similar trials in Sarasota, FL

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Prostate cancer
By specialty
OncologyProstate oncologyMen's healthUrology
By research site
Florida Cancer Specialists & Research Institute· Sarasota, FLStart Midwest· Grand Rapids, MISTART Mountain Region· West Valley City, UT

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