Prevalence of Fibromyalgia in Patients With Plaque Psoriasis

Sponsor
Assiut University
Study ID
NCT07773766
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Study Details

This observational study aims to determine how common fibromyalgia syndrome and central sensitization are in adults with plaque psoriasis compared to healthy individuals. Plaque psoriasis is a chronic inflammatory skin disease that can affect the entire body, which may increase the risk of developing chronic pain conditions. Fibromyalgia causes widespread musculoskeletal pain, fatigue, and sleep disturbances, while central sensitization involves the central nervous system becoming highly sensitive to pain. Researchers will evaluate 55 adult patients diagnosed with plaque psoriasis and 55 age- and sex-matched healthy volunteers at the Dermatology Outpatient Clinic at Assiut University Hospital. Participants will undergo a clinical examination to assess their psoriasis severity and will complete standardized questionnaires to evaluate pain intensity, fibromyalgia symptoms, central sensitization, and overall quality of life. The findings of this study may help doctors better understand these overlapping conditions to improve the early identification and management of pain in patients with psoriasis.

Key Dates

First listed
Aug 19, 2026
Start date
Sep 30, 2026
Status verified
Aug 2026
Primary completion
Sep 30, 2027
Completion
Oct 31, 2027

Study Design

Enrollment
110 participants (estimated)

Arms

  • Arm: Patients with Plaque Psoriasis
    Adult male and female patients (18 years of age and older) who have been clinically diagnosed with plaque psoriasis.
  • Arm: Healthy Controls
    Apparently healthy, age- and sex-matched volunteers with no history of psoriasis, psoriatic arthritis, or other chronic inflammatory or rheumatic diseases.

Primary Outcome Measure

Percentage of Participants Diagnosed With Fibromyalgia Syndrome [ Time Frame: Baseline ]

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