A Study for Postoperative Delirium in Older Patients With Intracranial Tumors

Sponsor
Beijing Tiantan Hospital
Study ID
NCT07797660
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
60 Years - N/A
Healthy Volunteers
Not accepted

Study Details

Postoperative delirium is a common acute central nervous system syndrome, which often occurs 1-5 days after surgery. Postoperative delirium can prolong the length of hospital stay, increase the mortality rate, and is also associated with long-term postoperative cognitive dysfunction. However, the pathogenesis of postoperative delirium in elderly patients undergoing neurosurgical procedures, who are at high risk for ostoperative delirium, remains unclear. This study aims to elucidate the underlying mechanisms of postoperative delirium in this population and inform the development of effective prevention and treatment strategies.

Key Dates

First listed
Sep 1, 2026
Start date
Aug 30, 2026
Status verified
Aug 2026
Primary completion
Aug 30, 2027
Completion
Sep 30, 2027

Study Design

Enrollment
164 participants (estimated)

Arms

  • Arm: Intraoperative hypotension
  • Arm: Without intraoperative hypotension

Primary Outcome Measure

The association between intraoperative hypotension and postoperative delirium [ Time Frame: The surgery day and twice a day (from 8:00 to 10:00 and from 18:00 to 20:00) during the first postoperative 5 days. ]

Central Contacts

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