Pilot Study of the Sage Guard for Oral Cavity Protection

Part of paid clinical trials in Charlotte, North Carolina.

Sponsor
Wake Forest University Health Sciences
Study ID
NCT07806812
Status
Not Yet Recruiting

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Conditions

  • Intubated Patients

Eligibility Criteria

Sex
ALL
Age
13 Years - 65 Years
Healthy Volunteers
Not accepted

Interventions

  • Sage Guard oral protection device — DEVICE
    The study device is a single-use mouth device made of a soft plastic material (thermoplastic polyurethane). It has side bite blocks that help keep the teeth apart, a center support that helps hold the breathing tube in place, and tongue guards that help protect the tongue from injury. The device is designed for use in patients with an endotracheal (breathing) tube to help prevent injury to the mouth and tongue caused by biting and to help keep the breathing tube stable.

Study Details

During placement of a breathing tube, a soft device will be placed in the mouth to help keep the teeth apart and hold the tongue out of the way. This device is designed to help protect the mouth and throat from injury caused by biting, which can lead to swelling or infection. It may also help keep the breathing tube in place and prevent damage to the tube from being bitten. The study will evaluate how safe the device is and how easy it is for healthcare providers to use in patients receiving care in the Intensive Care Unit (ICU).

Key Dates

First listed
Sep 8, 2026
Start date
Sep 30, 2026
Status verified
Aug 2026
Primary completion
Dec 31, 2027
Completion
Jan 31, 2028

Study Design

Enrollment
40 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION

Arms

  • Experimental: Sage Guard Intervention
    Participants will wear the Sage Guard device during the study procedure to evaluate its feasibility, safety, usability, and effectiveness in protecting vital structures of the oral cavity.

Primary Outcome Measure

Incidence of oral trauma in intubated patients [ Time Frame: Daily assessment up to Day 21 ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Atrium Health - Carolinas Medical CenterCharlotteNorth Carolina28203
Kerry Syer, BA, RDH
704-355-1704
Jenene Noll, RN
704-355-9120
Jesus A Valdez, DDS (PRINCIPAL_INVESTIGATOR)

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