As of July 2026, 506 paid clinical trials are recruiting in Charlotte, North Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Charlotte offers studies at sites including Levine Cancer Institute for conditions such as Multiple Myeloma, Breast Cancer, Acute Myeloid Leukemia, Heart Failure. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Researchers run research studies in Charlotte, NC at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Levine Cancer Institute | Multiple Myeloma, Cancer, Breast Cancer | 56 |
| Carolinas Medical Center/Levine Cancer Institute | Acute Myeloid Leukemia, Acute Myeloid Leukemia Post Cytotoxic Therapy, B Acute Lymphoblastic Leukemia | 47 |
| Atrium Health | Aortic Dissection, Crohn Disease, Acute Cerebrovascular Disease | 27 |
| Novant Health Presbyterian Medical Center | Acute Myeloid Leukemia, Acute Myeloid Leukemia Post Cytotoxic Therapy, Anatomic Stage II Breast Cancer AJCC v8 | 27 |
| Atrium Health Pineville/LCI-Pineville | Breast Cancer, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 16 |
| Atrium Health University City/LCI-University | Breast Cancer, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 16 |
| Atrium Health Carolinas Medical Center | Osteomyelitis Tibia, Tibial Fractures, Articular Fractures | 12 |
| Levine Cancer Institute-Ballantyne | Breast Cancer, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 12 |
| Levine Cancer Institute-SouthPark | Breast Cancer, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 11 |
| Atrium Health Levine Cancer | Adolescent Cancer, Breast Cancer, Cancer | 9 |
| Atrium Health Levine Cancer Institute | Breast Cancer, Carcinoma, Squamous Cell, ER-positive Breast Cancer | 9 |
| Carolinas Medical Center | Acute Cerebrovascular Disease, Anaplastic Lymphoma Kinase-positive, Cardiovascular Diseases | 9 |
| Levine Children's Hospital | Neuroblastoma, Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL) | 9 |
| GSK Investigational Site | Breast Neoplasms, Chickenpox, HIV Infections | 7 |
| OrthoCarolina Research Institute | Acute Comminuted Articular Fracture of Elbow Joint Surfaces, Adolescent Idiopathic Scoliosis (AIS), Advanced Rheumatoid Arthritis | 7 |
| Joint and Muscle Research Institute | Arthritis, Psoriatic, Lupus Erythematosus, Systemic, Lupus Nephritis | 6 |
| Novant Health Cancer Institute | Acute Myeloid Leukemia, in Relapse, MDS (Myelodysplastic Syndrome), Acute Myeloid Leukemia Refractory | 6 |
| OrthoCarolina | Chronic Osteomyelitis, Degenerative Disc Disease, Diabetic Foot Osteomyelitis | 6 |
| DJL Clinical Research, PLLC | Systemic Lupus Erythematosus (SLE), Hidradenitis Suppurativa, Lupus Erythematosus, Systemic | 5 |
| New Hope Clinical Research | Major Depressive Disorder, Agitation, Alzheimer Disease | 5 |
| Atrium Health Levine Children's Hospital | Delivery Room Resuscitation, Fabry Disease, Glomerulosclerosis, Focal Segmental | 4 |
| DelRicht Research | Bipolar Depression, Bipolar Disorder, Bipolar I Disorder | 4 |
| Levine Cancer Center | Advanced Solid Tumors Cancer, B Cell Lymphoma, B-Cell Non-Hodgkin's Lymphoma | 4 |
| Novant Health | AV Block, CLL/SLL, Heart Failure | 4 |
| Novant Health Presbyterian Hemby Children's Hospital | Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Mixed Phenotype Acute Leukemia | 4 |
Recruiting trials in Charlotte grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
There are approximately 506 recruiting clinical trials in Charlotte, North Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in Charlotte compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in Charlotte include Multiple Myeloma (14), Breast Cancer (10), Acute Myeloid Leukemia (9), Heart Failure (8), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Charlotte on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in Charlotte include Levine Cancer Institute, Carolinas Medical Center/Levine Cancer Institute, Atrium Health, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in Charlotte are Cancer & tumors (176), Neurology & pain (29), Cardiovascular (24). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.