Feasibility and Effectiveness of Sentinel Lymph Node Biopsy in Inflammatory Breast Cancer
Part of paid clinical trials in Cleveland, Ohio.
- Sponsor
- Case Comprehensive Cancer Center
- Study ID
- NCT07876986
- Status
- Not Yet Recruiting
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Conditions
Eligibility Criteria
- Sex
- FEMALE
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Sentinel node biopsy with blue dye and radioisotope — DIAGNOSTIC_TESTParticipants will be injected with blue dye and radioisotope tracer into the breast of tumor that drains into the first axillary lymph nodes during their planned surgical procedure so that the sentinel lymph nodes can be sampled.
Study Details
This study is for participants with inflammatory breast cancer (IBC). The purpose of this study is to find out whether it is possible to take a sample of underarm lymph nodes for participants with IBC. The participants will undergo sentinel lymph node biopsy (SLNB) in addition to full axillary lymph node dissection (ALND) during the planned breast cancer surgery. Participants enrolled in the study will first be injected with tracer, then undergo SLNB, and then undergo full ALND.
Key Dates
- First listed
- Oct 15, 2026
- Start date
- Jan 1, 2027
- Status verified
- Oct 2026
- Primary completion
- Apr 1, 2028
- Completion
- Apr 1, 2028
Study Design
- Enrollment
- 20 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- DIAGNOSTIC
Arms
- Experimental: Inflammatory Breast CancerFor participants diagnosed with IBC
Primary Outcome Measure
Rate of identification of sentinel lymph nodes [ Time Frame: at day 1 ]
Central Contacts
- Stephanie Valente, DO(216) 492-2235
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| Cleveland Clinic Foundation | Cleveland | Ohio | 44111 | Stephanie Valente, DO (PRINCIPAL_INVESTIGATOR) |
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