Retatrutide Clinical Trials (2026): 19 Studies for Obesity & Overweight
Hipa.ai Research · Source: ClinicalTrials.gov / AACT
Synced daily from ClinicalTrials.gov via AACT. Last sync: .
19 Retatrutide clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 10 indications (including Obesity & Overweight) and 25,863 total planned enrollment. 14 Phase 3 Retatrutide trials and 2 Phase 2 are listed. 3 Retatrutide clinical trials are actively recruiting at 158 U.S. sites across 34 states. Most recent activity: NCT07165028 (Aug 2032).
Where to Participate: All Retatrutide Trial Sites in the U.S. (158 sites across 34 states)
Every actively recruiting Retatrutidetrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.
| State | Facility | City | Trial | Map |
|---|---|---|---|---|
| AL | MFA Clinical Research | Tuscaloosa35405 | NCT07165028 | Map |
| AZ | MD First Research - Chandler | Chandler85286 | NCT07035093 | Map |
| AZ | The Institute for Liver Health II dba Arizona Clinical Trials - Chandler | Chandler85224 | NCT07165028 | Map |
| AZ | Spectrum Research Institute | Gilbert85297 | NCT07165028 | Map |
| AZ | The Institute for Liver Health II dba Arizona Liver Health - Peoria | Peoria85381 | NCT07165028 | Map |
| AZ | Epic Medical Research-Sun City | Sun City85351 | NCT07165028 | Map |
| AZ | Del Sol Research Management, LLC | Tucson85715 | NCT07165028 | Map |
| AZ | The Institute for Liver Health II dba Arizona Clinical Trials - Tucson | Tucson85712 | NCT07165028 | Map |
| AZ | Tucson Orthopaedic Institute - North Wyatt Drive | Tucson85712 | NCT07035093 | Map |
| AR | Arkansas Gastroenterology - North Little Rock | North Little Rock72117 | NCT07165028 | Map |
| CA | San Fernando Valley Health Institute | Canoga Park91304 | NCT07165028 | Map |
| CA | Ark Clinical Research - Fountain Valley | Fountain Valley92708 | NCT07035093 | Map |
| CA | Ark Clinical Research - Fountain Valley | Fountain Valley92708 | NCT07165028 | Map |
| CA | Fresno Clinical Research Center | Fresno93720 | NCT07165028 | Map |
| CA | St Joseph Heritage Healthcare | Fullerton92835 | NCT07035093 | Map |
| CA | UCSD - Altman Clinical and Translational Research Institute (ACTRI) | La Jolla92037 | NCT07165028 | Map |
| CA | Orange County Research Center | Lake Forest92630 | NCT07165028 | Map |
| CA | Om Research LLC | Lancaster93534 | NCT07165028 | Map |
| CA | Ark Clinical Research | Long Beach90815 | NCT07165028 | Map |
| CA | Clinical Research Institute | Los Angeles90048 | NCT07035093 | Map |
| CA | Los Angeles Institute for Metabolic Research | Los Angeles90015 | NCT07165028 | Map |
| CA | United Medical Doctors - Murrieta | Murrieta92563 | NCT07165028 | Map |
| CA | Knowledge Research Center | Orange92868 | NCT07165028 | Map |
| CA | California Liver Research Center | Pasadena91105 | NCT07165028 | Map |
| CA | Artemis Institute for Clinical Research | Riverside92503 | NCT07165028 | Map |
| CA | Artemis Institute for Clinical Research | San Diego92123 | NCT07035093 | Map |
| CA | Medical Associates Research Group | San Diego92123 | NCT07165028 | Map |
| CA | Quest Clinical Research | San Francisco94115 | NCT07165028 | Map |
| CO | University of Colorado Anschutz Medical Campus | Aurora80045 | NCT07165028 | Map |
| CO | Alpine Clinical Research Center | Boulder80301 | NCT07035093 | Map |
| CO | South Denver Gastroenterology | Englewood80113 | NCT07165028 | Map |
| CT | Medical Research Center of Connecticut | Hamden06518 | NCT07165028 | Map |
| FL | K2 Medical Research WINTER GARDEN | Clermont34711 | NCT07165028 | Map |
| FL | K2 Medical Research - Daytona Beach | Daytona Beach32114 | NCT07035093 | Map |
| FL | K2 Medical Research - Daytona Beach | Daytona Beach32114 | NCT07165028 | Map |
| FL | Care Access - Delray Beach | Delray Beach33484 | NCT07165028 | Map |
| FL | AMR Clinical | Doral33172 | NCT07165028 | Map |
| FL | Southwest General Healthcare Center | Fort Myers33907 | NCT07165028 | Map |
| FL | University of Florida College of Medicine | Gainesville32610 | NCT07165028 | Map |
| FL | Encore Medical Research | Hollywood33024 | NCT07165028 | Map |
| FL | Nature Coast Clinical Research - Inverness | Inverness34452 | NCT07165028 | Map |
| FL | Encore Borland-Groover Clinical Research | Jacksonville32256 | NCT07165028 | Map |
| FL | Health Awareness | Jupiter33458 | NCT07165028 | Map |
| FL | K2 MEDICAL Research THE VILLAGES | Lady Lake32159 | NCT07165028 | Map |
| FL | Florida Research Institute | Lakewood Rch34211 | NCT07165028 | Map |
| FL | Tampa Bay Medical Research - Largo | Largo33777 | NCT07165028 | Map |
| FL | Evolution Clinical Trials | Miami33122-1722 | NCT07165028 | Map |
| FL | Flourish Research - Miami, LLC | Miami33135 | NCT07035093 | Map |
| FL | Floridian Clinical Research, LLC | Miami Lakes33016-1518 | NCT07165028 | Map |
| FL | GI PROS Research | Naples34102 | NCT07165028 | Map |
| FL | Charter Research - Orlando | Orlando32803 | NCT07165028 | Map |
| FL | Headlands Research Orlando | Orlando32806 | NCT07165028 | Map |
| FL | Progressive Medical Research | Port Orange32127 | NCT07165028 | Map |
| FL | Covenant Metabolic Specialists - Riverview | Riverview33578 | NCT07165028 | Map |
| FL | Care Access - St. Petersburg | St. Petersburg33710 | NCT07165028 | Map |
| FL | IMA Clinical Research St. Petersburg | St. Petersburg33704 | NCT07035093 | Map |
| FL | Care Access - Tamarac | Tamarac33321 | NCT07165028 | Map |
| FL | Care Access - Tampa | Tampa33625 | NCT07035093 | Map |
| FL | Charter Research - Lady Lake | The Villages32162 | NCT07035093 | Map |
| FL | Covenant Metabolic Specialists, LLC | University Park34201 | NCT07165028 | Map |
| FL | Conquest Research | Winter Park32789 | NCT07035093 | Map |
| GA | Southeast Clinical Research Center | Dalton30720 | NCT07165028 | Map |
| GA | Gastrointestinal Specialists of Georgia | Marietta30060 | NCT07165028 | Map |
| GA | Rophe Adult and Pediatric Medicine/SKYCRNG | Union City30291 | NCT07165028 | Map |
| IN | Indiana University Health University Hospital | Indianapolis46202 | NCT07165028 | Map |
| IN | Deaconess Clinic- Gateway | Newburgh47630 | NCT07165028 | Map |
| IN | Digestive Research Alliance of Michiana | South Bend46635 | NCT07165028 | Map |
| IA | Iowa Diabetes and Endocrinology Research Center | West Des Moines50266 | NCT07165028 | Map |
| KS | AMR Clinical | El Dorado67042 | NCT07165028 | Map |
| KS | Johnson County Clinical Trials | Lenexa66219 | NCT07165028 | Map |
| KS | Cotton O'Neil Clinical Research Center | Topeka66606 | NCT07035093 | Map |
| KS | Cotton O'Neil Digestive Health Center | Topeka66606 | NCT07165028 | Map |
| KY | AMR Clinical | Lexington40509 | NCT07165028 | Map |
| LA | Delta Research Partners of Bastrop, LLC | Bastrop71220 | NCT07165028 | Map |
| LA | Care Access - Lake Charles (Bayou Pines) | Lake Charles70601 | NCT07035093 | Map |
| LA | Tandem Clinical Research | Marrero70072 | NCT07165028 | Map |
| LA | Care Access - New Iberia | New Iberia70560 | NCT07165028 | Map |
| LA | Louisiana Research Center | Shreveport71105 | NCT07165028 | Map |
| LA | Delta Research Partners of West Monroe | West Monroe71291 | NCT07165028 | Map |
| MD | Mercy Medical Center - Baltimore | Baltimore21202 | NCT07165028 | Map |
| MD | Capital Digestive Care - Chevy Chase | Chevy Chase20815 | NCT07165028 | Map |
| MA | Lucida Clinical Trials | New Bedford02740 | NCT07165028 | Map |
| MA | MedVadis Research Corporation | Waltham02451 | NCT07035093 | Map |
| MI | Great Lakes Research Group, Inc. | Bay City48706 | NCT07035093 | Map |
| MI | Clinical Research Institute of Michigan, LLC | Clinton Township48038 | NCT07165028 | Map |
| MI | Great Lakes Research Institute | Southfield48075 | NCT07165028 | Map |
| MI | Arcturus Healthcare , PLC, Troy Internal Medicine Research Division | Troy48098 | NCT07165028 | Map |
| MN | MNGI Digestive Health | Minneapolis55413 | NCT07165028 | Map |
| MS | GI Associates - GIA and Endoscopy Center - Flowood | Flowood39232 | NCT07165028 | Map |
| MO | AMR Clinical | Kansas City64114 | NCT07165028 | Map |
| MO | Clinvest Headlands Llc | Springfield65807 | NCT07035093 | Map |
| NV | Excel Clinical Research, LLC | Las Vegas89109 | NCT07165028 | Map |
| NV | Jubilee Clinical Research NV. LLC | Las Vegas89106 | NCT07165028 | Map |
| NJ | Tandem Clinical Research - Freehold | Freehold07728 | NCT07165028 | Map |
| NJ | Clinical Research of Philadelphia | Pennington08534 | NCT07165028 | Map |
| NJ | The Cognitive and Research Center of New Jersey - Ridgewood | Ridgewood07450 | NCT07165028 | Map |
| NJ | IMA Clinical Research Warren | Warren Township07059 | NCT07165028 | Map |
| NM | Southwest Gastroenterology Associates | Albuquerque87109 | NCT07165028 | Map |
| NY | Research Foundation of SUNY - University of Buffalo | Buffalo14203 | NCT07165028 | Map |
| NY | IMA Clinical Research Manhattan | New York10036 | NCT07165028 | Map |
| NY | New York Gastroenterology Associates | New York10075 | NCT07165028 | Map |
| NY | Care Access - Yonkers | Yonkers10701 | NCT07165028 | Map |
| NC | Monroe Biomedical Research | Monroe28112 | NCT07165028 | Map |
| NC | Carteret Medical Group | Morehead City28557 | NCT07165028 | Map |
| NC | Center for Clinical Research | Winston-Salem27103 | NCT07035093 | Map |
| OH | Akron Gastro Research | Akron44320 | NCT07165028 | Map |
| OH | CRIOH | Westlake44145 | NCT07165028 | Map |
| PA | Altoona Center For Clinical Research | Duncansville16635 | NCT07035093 | Map |
| PA | US Digestive Health - Flourtown | Flourtown19031 | NCT07165028 | Map |
| PA | Penn Medicine: University of Pennsylvania Health System | Philadelphia19104 | NCT07165028 | Map |
| PA | US Digestive Health - Wyomissing | Wyomissing19610 | NCT07165028 | Map |
| RI | University Gastroenterology | Providence02905 | NCT07165028 | Map |
| SC | Columbia Digestive Health Research | Columbia29204 | NCT07165028 | Map |
| TN | Galen Medical Group - Galen Hepatology | Chattanooga37421 | NCT07165028 | Map |
| TN | Gastro One (Walnut Run Road) | Cordova38018 | NCT07165028 | Map |
| TN | New Phase Research and Development | Knoxville37909 | NCT07035093 | Map |
| TX | American Research Corporation | Austin78757 | NCT07165028 | Map |
| TX | FutureSearch Trials of Neurology | Austin78731 | NCT07035093 | Map |
| TX | IMA Clinical Research Austin | Austin78745 | NCT07165028 | Map |
| TX | Pinnacle Clinical Research | Austin78757 | NCT07165028 | Map |
| TX | Bellaire Clinical Research | Bellaire77401 | NCT07165028 | Map |
| TX | Headlands Horizons, LLC dba Headlands Research-Brownsville | Brownsville78526 | NCT07165028 | Map |
| TX | South Texas Research Institute - Brownsville | Brownsville78520 | NCT07165028 | Map |
| TX | Mercy Family Clinic | Dallas75208 | NCT07035093 | Map |
| TX | Soma Clinical Trials | Denison75020 | NCT07165028 | Map |
| TX | Epic Medical Research - DeSoto | DeSoto75115 | NCT07165028 | Map |
| TX | South Texas Research Institute | Edinburg78539 | NCT07165028 | Map |
| TX | Dallas Research Institute | Farmers Branch75234 | NCT07165028 | Map |
| TX | Care United Research, LLC | Forney75126 | NCT07165028 | Map |
| TX | GI Alliance - Fort Worth | Fort Worth76104 | NCT07165028 | Map |
| TX | Biopharma Informatic, LLC | Houston77084 | NCT07165028 | Map |
| TX | Care Access - Houston | Houston77054 | NCT07165028 | Map |
| TX | Houston Research Institute | Houston77079 | NCT07035093 | Map |
| TX | Houston Research Institute | Houston77079 | NCT07165028 | Map |
| TX | HRI- Medical Center | Houston77004 | NCT07165028 | Map |
| TX | Research Physicians Network, LLC | Houston77089 | NCT07165028 | Map |
| TX | Biopharma Informatic, LLC | McAllen78503 | NCT07165028 | Map |
| TX | DHR Health Institute for Research and Development (Administrative Office & Laboratory) | McAllen78504 | NCT07165028 | Map |
| TX | Southern Endocrinology Associates | Mesquite75149 | NCT07165028 | Map |
| TX | HRI Pasadena | Pasadena77505 | NCT07165028 | Map |
| TX | American Research Corporation at Texas Liver Institute | San Antonio78215 | NCT07165028 | Map |
| TX | Clinical Trials of Texas, LLC dba Flourish Research | San Antonio78229 | NCT07165028 | Map |
| TX | IMA Clinical Research San Antonio | San Antonio78229 | NCT07165028 | Map |
| TX | Consano Clinical Research, LLC | Shavano Park78231 | NCT07165028 | Map |
| TX | GI Alliance - Southlake | Southlake76092 | NCT07165028 | Map |
| TX | Houston Research Institute (HRI) - Sugar Land | Sugar Land77479 | NCT07165028 | Map |
| TX | Texas Valley Clinical Research | Weslaco78596 | NCT07165028 | Map |
| TX | Medrasa Clinical Research | Wylie75098 | NCT07165028 | Map |
| UT | Care Access - Ogden | Ogden84403 | NCT07165028 | Map |
| UT | Advanced Research Institute - Sandy | Sandy City84070 | NCT07165028 | Map |
| VA | Sovah Clinical Research-River District | Danville24541 | NCT07035093 | Map |
| VA | Eximia Research - Norfolk | Norfolk23502 | NCT07165028 | Map |
| VA | Richmond Veterans Affairs Medical Center (Richmond VA Medical Center) | Richmond23249 | NCT07165028 | Map |
| VA | Gastroenterology Consultants of Southwest Virginia | Roanoke24014 | NCT07165028 | Map |
| WA | Washington Gastroenterology - Bellevue | Bellevue98004 | NCT07165028 | Map |
| WA | UW Medicine Diabetes Institute | Seattle98109 | NCT07165028 | Map |
| WA | Washington Gastroenterology - Tacoma | Tacoma98405 | NCT07165028 | Map |
| WV | CAMC Health Education and Research Institute Inc | Charleston25304 | NCT07165028 | Map |
Retatrutide clinical trials at a glance: phase × recruitment status
| Phase | recruiting | active not recruiting | completed | Total |
|---|---|---|---|---|
| P1 | 1 | 2 | 3 | |
| P2 | 1 | 1 | 2 | |
| P3 | 2 | 9 | 3 | 14 |
Recruiting Retatrutide clinical trials (3)
Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).
| NCT ID | Title | Phase | Indication | Enrollment | Started |
|---|---|---|---|---|---|
| NCT07165028 | A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes) | P3 | Metabolic Dysfunction-Associated Steatotic Liver Disease | 4,500 | Oct 2025 |
| NCT07467447 | GZBFEffect of LY3437943 Versus Placebo in Participants Who Have Obesity or Are Overweight | P2 | Obesity | 300 | Feb 2026 |
| NCT07035093 | TRIUMPH-7A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back Pain | P3 | Obesity | 586 | May 2025 |
Retatrutide clinical trials by indication
Obesity (9)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT07357415 | TRIUMPH-9 | P3 | active not recruiting | A Study of Retatrutide (LY3437943) in Participants Without Type 2 Diabetes Who Have Obesity or Overweight |
| NCT06859268 | TRIUMPH-6 | P3 | active not recruiting | A Study of Retatrutide (LY3437943) in the Maintenance of Weight Reduction in Individuals With Obesity |
| NCT07467447 | GZBF | P2 | recruiting | Effect of LY3437943 Versus Placebo in Participants Who Have Obesity or Are Overweight |
| NCT07035093 | TRIUMPH-7 | P3 | recruiting | A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back Pain |
| NCT07232719 | TRIUMPH-8 | P3 | active not recruiting | A Study of Retatrutide (LY3437943) in Participants With Obesity or Overweight |
| NCT06662383 | TRIUMPH-5 | P3 | active not recruiting | A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have Obesity |
| NCT05882045 | TRIUMPH-3 | P3 | active not recruiting | A Study of Retatrutide (LY3437943) in Participants With Obesity and Cardiovascular Disease |
| NCT05929066 | TRIUMPH-1 | P3 | completed | A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight |
| + 1 more, see All trials below. | ||||
Type 2 Diabetes (2)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT06297603 | TRANSCEND-T2D-3 | P3 | active not recruiting | Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3) |
| NCT05929079 | TRIUMPH-2 | P3 | active not recruiting | A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have Obesity or Overweight |
Metabolic Dysfunction-Associated Steatotic Liver Disease (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT07165028 | — | P3 | recruiting | A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes) |
Type 2 Diabetes Mellitus (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT06982846 | — | P1 | completed | A Study to Investigate the Response of Participants With Type 2 Diabetes Mellitus on Once-Weekly Retatrutide to Hypoglycemia |
Diabetes Mellitus (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT06982859 | — | P1 | active not recruiting | A Study to Evaluate the Effect of Retatrutide on Insulin Secretion and Insulin Sensitivity in Adult Participants With Type 2 Diabetes Mellitus |
Healthy (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT06808802 | LY3437943 | P1 | completed | To Investigate the Effect of Retatrutide (LY3437943) on Metoprolol Pharmacokinetics in Healthy Participants |
Atherosclerotic Cardiovascular Disease (ASCVD) (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT06383390 | — | P3 | active not recruiting | The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes) |
Diabetes Type 2 (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT06354660 | TRANSCEND-T2D-1 | P3 | completed | Effect of Retatrutide Compared With Placebo in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise Alone (TRANSCEND-T2D-1) |
Diabetes Mellitus, Type 2 (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT06260722 | TRANSCEND-T2D-2 | P3 | active not recruiting | Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin With or Without SGLT2 Inhibitor (TRANSCEND-T2D-2) |
Overweight or Obesity (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT05936151 | LY3437943 | P2 | completed | A Study of Retatrutide (LY3437943) on Renal Function in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes |
Retatrutide pivotal trial highlights (Phase 2/3/4)
Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.
| Acronym | NCT | Phase | Status | Indication | Enrollment | PubMed |
|---|---|---|---|---|---|---|
| TRIUMPH-9 | NCT07357415 | P3 | active not recruiting | Obesity | 600 | — |
| TRIUMPH-6 | NCT06859268 | P3 | active not recruiting | Obesity | 643 | — |
| TRIUMPH-7 | NCT07035093 | P3 | recruiting | Obesity | 586 | — |
| TRIUMPH-8 | NCT07232719 | P3 | active not recruiting | Obesity | 250 | — |
| TRANSCEND-T2D-2 | NCT06260722 | P3 | active not recruiting | Diabetes Mellitus, Type 2 | 1,250 | — |
| TRIUMPH-5 | NCT06662383 | P3 | active not recruiting | Obesity | 800 | — |
| TRANSCEND-T2D-3 | NCT06297603 | P3 | active not recruiting | Type 2 Diabetes | 320 | — |
| TRIUMPH-2 | NCT05929079 | P3 | active not recruiting | Type 2 Diabetes | 1,000 | — |
| TRIUMPH-3 | NCT05882045 | P3 | active not recruiting | Obesity | 1,946 | — |
| TRIUMPH-1 | NCT05929066 | P3 | completed | Obesity | 2,335 | — |
| TRANSCEND-T2D-1 | NCT06354660 | P3 | completed | Diabetes Type 2 | 537 | — |
| TRIUMPH-4 | NCT05931367 | P3 | completed | Obesity | 445 | — |
| GZBF | NCT07467447 | P2 | recruiting | Obesity | 300 | — |
| LY3437943 | NCT05936151 | P2 | completed | Overweight or Obesity | 146 | — |
All Retatrutide trials (19)
Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.
| NCT ID | Acronym | Title | Phase | Status | Enrollment | Sponsor | Started |
|---|---|---|---|---|---|---|---|
| NCT07165028 | A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes) | P3 | recruiting | 4,500 | Eli Lilly and Company | Oct 2025 | |
| NCT06383390 | The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes) | P3 | active not recruiting | 10,000 | Eli Lilly and Company | Apr 2024 | |
| NCT07357415 | TRIUMPH-9 | A Study of Retatrutide (LY3437943) in Participants Without Type 2 Diabetes Who Have Obesity or Overweight | P3 | active not recruiting | 600 | Eli Lilly and Company | Jan 2026 |
| NCT06859268 | TRIUMPH-6 | A Study of Retatrutide (LY3437943) in the Maintenance of Weight Reduction in Individuals With Obesity | P3 | active not recruiting | 643 | Eli Lilly and Company | Mar 2025 |
| NCT07467447 | GZBF | Effect of LY3437943 Versus Placebo in Participants Who Have Obesity or Are Overweight | P2 | recruiting | 300 | Hudson Biotech | Feb 2026 |
| NCT07035093 | TRIUMPH-7 | A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back Pain | P3 | recruiting | 586 | Eli Lilly and Company | May 2025 |
| NCT07232719 | TRIUMPH-8 | A Study of Retatrutide (LY3437943) in Participants With Obesity or Overweight | P3 | active not recruiting | 250 | Eli Lilly and Company | Nov 2025 |
| NCT06260722 | TRANSCEND-T2D-2 | Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin With or Without SGLT2 Inhibitor (TRANSCEND-T2D-2) | P3 | active not recruiting | 1,250 | Eli Lilly and Company | Feb 2024 |
| NCT06982859 | A Study to Evaluate the Effect of Retatrutide on Insulin Secretion and Insulin Sensitivity in Adult Participants With Type 2 Diabetes Mellitus | P1 | active not recruiting | 95 | Eli Lilly and Company | Jun 2025 | |
| NCT06662383 | TRIUMPH-5 | A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have Obesity | P3 | active not recruiting | 800 | Eli Lilly and Company | Nov 2024 |
| NCT06297603 | TRANSCEND-T2D-3 | Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3) | P3 | active not recruiting | 320 | Eli Lilly and Company | Mar 2024 |
| NCT05929079 | TRIUMPH-2 | A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have Obesity or Overweight | P3 | active not recruiting | 1,000 | Eli Lilly and Company | Jul 2023 |
| NCT05882045 | TRIUMPH-3 | A Study of Retatrutide (LY3437943) in Participants With Obesity and Cardiovascular Disease | P3 | active not recruiting | 1,946 | Eli Lilly and Company | May 2023 |
| NCT06982846 | A Study to Investigate the Response of Participants With Type 2 Diabetes Mellitus on Once-Weekly Retatrutide to Hypoglycemia | P1 | completed | 80 | Eli Lilly and Company | Jun 2025 | |
| NCT05929066 | TRIUMPH-1 | A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight | P3 | completed | 2,335 | Eli Lilly and Company | Jul 2023 |
| NCT06354660 | TRANSCEND-T2D-1 | Effect of Retatrutide Compared With Placebo in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise Alone (TRANSCEND-T2D-1) | P3 | completed | 537 | Eli Lilly and Company | Apr 2024 |
| NCT05931367 | TRIUMPH-4 | A Study of Retatrutide (LY3437943) Once Weekly in Participants Who Have Obesity or Overweight and Osteoarthritis of the Knee | P3 | completed | 445 | Eli Lilly and Company | Aug 2023 |
| NCT05936151 | LY3437943 | A Study of Retatrutide (LY3437943) on Renal Function in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes | P2 | completed | 146 | Eli Lilly and Company | Jul 2023 |
| NCT06808802 | LY3437943 | To Investigate the Effect of Retatrutide (LY3437943) on Metoprolol Pharmacokinetics in Healthy Participants | P1 | completed | 30 | Eli Lilly and Company | Feb 2025 |
Retatrutide clinical trials: frequently asked questions
- How many Retatrutide clinical trials are there?
- 19 Retatrutide clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 3 are actively recruiting participants. 6 are marked completed.
- Are Retatrutide clinical trials recruiting in 2026?
- Yes — 3 Retatrutide trials are actively recruiting in 2026, with 158 U.S. sites across 34 states. See the recruiting trials and the per-state site list further down this page.
- What conditions is Retatrutide being studied for?
- Retatrutide is being studied for Obesity, Overweight, Type 2 Diabetes, Obstructive Sleep Apnea, CKD and 14 more. The trials are grouped by indication on this page.
- What phase is Retatrutide in?
- Retatrutide clinical trials span 14 Phase 3, 2 Phase 2, 3 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
- Who sponsors Retatrutide clinical trials?
- The lead sponsor across the most Retatrutide trials is Eli Lilly and Company, with 1 additional lead sponsor listed in the data. Each trial row links to the full study detail page including sponsor information.
Sources and methodology
Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming Retatrutideas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.
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