A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back Pain

Part of paid clinical trials in Chandler, Arizona.

Sponsor
Eli Lilly and Company
Study ID
NCT07035093
Phase
PHASE3
Status
Active Not Recruiting

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Retatrutide — DRUG
    Administered SC
  • Placebo — DRUG
    Administered SC

Study Details

The main purpose of this study is to evaluate the efficacy and safety of retatrutide in relieving chronic low back pain in participants who have obesity or overweight. Participation in the study will last about 80 weeks.

Key Dates

First listed
Jun 24, 2025
Start date
May 29, 2025
Status verified
Jul 2026
Primary completion
Sep 30, 2027
Completion
Sep 30, 2027

Study Design

Enrollment
586 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Retatrutide
    Participants will receive Retatrutide subcutaneously (SC)
  • Placebo Comparator: Placebo
    Participants will receive Placebo SC

Primary Outcome Measure

Change from Baseline in Pain Intensity Per Numeric Rating Scale [ Time Frame: Baseline, up to 72 weeks ]

Locations (25)

FacilityCityStateZIPSite coordinators
MD First Research - ChandlerChandlerArizona85286-
Tucson Orthopaedic Institute - North Wyatt DriveTucsonArizona85712-
Ark Clinical Research - Fountain ValleyFountain ValleyCalifornia92708-
St Joseph Heritage HealthcareFullertonCalifornia92835-
Clinical Research InstituteLos AngelesCalifornia90048-
Artemis Institute for Clinical ResearchSan DiegoCalifornia92123-
Alpine Clinical Research CenterBoulderColorado80301-
K2 Medical Research - Daytona BeachDaytona BeachFlorida32114-
Flourish Research - Miami, LLCMiamiFlorida33135-
IMA Clinical Research St. PetersburgSt. PetersburgFlorida33704-
Care Access - TampaTampaFlorida33625-
Charter Research - Lady LakeThe VillagesFlorida32162-
Conquest ResearchWinter ParkFlorida32789-
Cotton O'Neil Clinical Research CenterTopekaKansas66606-
Care Access - Lake Charles (Bayou Pines)Lake CharlesLouisiana70601-
MedVadis Research CorporationWalthamMassachusetts02451-
Great Lakes Research Group, Inc.Bay CityMichigan48706-
Clinvest Headlands LlcSpringfieldMissouri65807-
Center for Clinical ResearchWinston-SalemNorth Carolina27103-
Altoona Center For Clinical ResearchDuncansvillePennsylvania16635-
New Phase Research and DevelopmentKnoxvilleTennessee37909-
FutureSearch Trials of NeurologyAustinTexas78731-
Mercy Family ClinicDallasTexas75208-
Houston Research InstituteHoustonTexas77079-
Sovah Clinical Research-River DistrictDanvilleVirginia24541-

Find similar trials in Chandler, AZ

Nationwide
Obesity / overweight trialsEndocrinology trialsMetabolic health trialsWeight loss trials
By condition
Obesity / overweight
By specialty
EndocrinologyMetabolic healthWeight loss
By research site
MD First Research - Chandler· Chandler, AZTucson Orthopaedic Institute - North Wyatt Drive· Tucson, AZArk Clinical Research - Fountain Valley· Fountain Valley, CASt Joseph Heritage Healthcare· Fullerton, CAClinical Research Institute· Los Angeles, CAArtemis Institute for Clinical Research· San Diego, CA

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