Paid Clinical Trials in Columbia, MD
As of August 2026, 80 paid clinical trials are recruiting in Columbia, Maryland. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Columbia offers studies at sites including Central Maryland Radiation Oncology in Howard County for conditions such as Breast Cancer, Carcinoma, Non-Small-Cell Lung, Obesity, Overweight. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Columbia
Trials by drug in Columbia
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Newly added in Columbia
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
77 clinical trials
A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)
Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With Uncontrolled Gout
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
Efficacy and Safety of Ribupatide Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes
Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-1)
ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease
A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)
Pelacarsen Roll-over Extension Program
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
Real-world Experience Using Nemolizumab in the Treatment of Moderate-to-Severe Atopic Dermatitis in Adolescents & Adults
Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
Proof-of-Concept Study Evaluating Total Body Weight, Physical Function & Safety of Enobosarm in Patients Treated With GLP-1 Receptor Agonist, for Weight Loss
A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)
ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis
Efficacy and Safety of Ribupatide in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes
A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002)
Beamion PANTUMOR-1: A Study to Test Whether Zongertinib Helps People With Advanced Cancers With HER2 Alterations
ATLAS (AltaValve) Pivotal Trial
A Study to Assess Efficacy and Safety of Empasiprubart Versus IVIg in Adults With CIDP
ZEN003694 and Enzalutamide Versus Enzalutamide Monotherapy in Metastatic Castration-Resistant Prostate Cancer
CardiolRx in Recurrent Pericarditis (MAVERIC Phase-3)
A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions
Top Research Study Locations in Columbia
Researchers run research studies in Columbia, MD at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Central Maryland Radiation Oncology in Howard County | Metastatic Malignant Neoplasm in the Brain, Stage IV Lung Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | 7 |
| Maryland Oncology Hematology, P.A. | Breast Cancer, Esophageal Adenocarcinoma, Essential Thrombocythemia | 7 |
| Centennial Medical Group | Obesity, Overweight, Atherosclerotic Cardiovascular Disease (ASCVD) | 6 |
| Central Maryland Radiation Oncology | Brain Tumor, Glioblastoma, Glioma | 5 |
| Johns Hopkins University | Atherosclerotic Cardiovascular Disease, Atherosclerotic Cardiovascular Disease (ASCVD), Cardiovascular Disease | 4 |
| Maryland Oncology Hematology | Breast Cancer, Colon Cancer, Colorectal Cancer | 4 |
| MedStar Health Research Institute | Degenerative Disc Disease, Leg Pain and/or Back Pain, Rotator Cuff Tear | 3 |
| Central Maryland Oncology Center | Breast Cancer, Breast Cancer Female | 2 |
| Erlanger Health System | AChR-Ab Seropositive Generalized Myasthenia Gravis, CIDP, CIDP - Chronic Inflammatory Demyelinating Polyneuropathy | 2 |
| Kailera Clinical Site | Obesity, Obesity With Diabetes, Overweight | 2 |
| Maryland Oncology Hematology - Columbia | Carcinoma, Non-Small-Cell Lung, Advanced Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung (NSCLC) | 2 |
| Maryland Oncology Hematology P.A. | Breast Cancer, Breast Neoplasms | 2 |
| Anxiety Treatment Center of Maryland | Anxiety Disorder of Childhood | 1 |
| Centennial Medical Group (CMG) | HOMA-IR, Mobility Disability, Obesity & Overweight | 1 |
| Centennial Medical Group Research Department | OSA | 1 |
| Charter Professional Center | Arthroplasty Complications, Fragility Fracture, Osteoporosis | 1 |
| Clearway Pain Solutions - Columbia | Lumbar Spinal Stenosis | 1 |
| Foundation Fighting Blindness | Achromatopsia, Bardet-Biedl Syndrome, Bassen-Kornzweig Syndrome | 1 |
| GSK Investigational Site | Neoplasms, Head and Neck | 1 |
| Galderma Investigational | Atopic Dermatitis | 1 |
| Johns Hopkins Community Physicians, Howard County Pediatrics | Adolescent Alcohol Use | 1 |
| Johns Hopkins Howard County Operating Room | Lumbar Spinal Stenosis | 1 |
| Johns Hopkins Surgery Centr- Howard County | Lumbar Spinal Stenosis | 1 |
| KUR Research at CMP | Diabetes Mellitus, Type 2, Metabolic Syndrome, PreDiabetes | 1 |
| Kur Research - Columbia Medical | Coronavirus Disease (COVID-19) | 1 |
Active & Upcoming Studies in Columbia (2026)
Recruiting trials in Columbia grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (34 active studies)
- Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma · Phase 3 · Immuneering Corporation
- Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer · Phase 2, Phase 3 · Pfizer
Diabetes & metabolic (7 active studies)
- Proof-of-Concept Study Evaluating Total Body Weight, Physical Function & Safety of Enobosarm in Patients Treated With GLP-1 Receptor Agonist, for Weight Loss · Phase 2 · Veru Inc.
- A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes · Phase 3 · Hoffmann-La Roche
Vaccines (2 active studies)
- A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease · Phase 3 · Pfizer
- A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023) · Phase 3 · Merck Sharp & Dohme LLC
Mental health & behavior (2 active studies)
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
- Efficacy Trial of the CALM Intervention · UConn Health
Neurology & pain (2 active studies)
- MagnetOs Flex Matrix Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion · Kuros Biosurgery AG
- Testing the Pain Clinical Practice Guideline · Phase 2 · University of Maryland, Baltimore
Eye & vision (2 active studies)
- Measuring the Effects of Netarsudil, Latanoprost, and Combination Therapy on Episcleral and Retinal Blood Flow in Ocular Hypertension and Glaucoma Suspects · Phase 4 · University of Maryland, Baltimore
- Inherited Retinal Degenerative Disease Registry · Foundation Fighting Blindness
Cardiovascular (1 active study)
- Measuring the Effects of Netarsudil, Latanoprost, and Combination Therapy on Episcleral and Retinal Blood Flow in Ocular Hypertension and Glaucoma Suspects · Phase 4 · University of Maryland, Baltimore
Pediatric (1 active study)
Common conditions studied in Columbia
- Breast Cancer (8 active studies)
- Carcinoma, Non-Small-Cell Lung (3 active studies)
- Obesity (3 active studies)
- Overweight (3 active studies)
- Brain Tumor (2 active studies)
- Cardiovascular Disease (2 active studies)
Leading research sponsors in Columbia
- University of Maryland, Baltimore
- Pfizer
- NRG Oncology
- AstraZeneca
- Eli Lilly and Company
Frequently asked questions
How many paid clinical trials are currently recruiting in Columbia?
There are approximately 80 recruiting clinical trials in Columbia, Maryland listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Columbia pay participants?
Most recruiting trials in Columbia compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Columbia?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Columbia?
The most common conditions under active study in Columbia include Breast Cancer (8), Carcinoma, Non-Small-Cell Lung (3), Obesity (3), Overweight (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Columbia?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Columbia on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Columbia?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Columbia?
Recruiting research sites in Columbia include Central Maryland Radiation Oncology in Howard County, Maryland Oncology Hematology, P.A., Centennial Medical Group, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Columbia right now?
The largest active categories in Columbia are Cancer & tumors (34), Diabetes & metabolic (7), Vaccines (2). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.