Clinical Trials at National Institutes of Health Clinical Center
As of September 2026, 582 paid clinical trials are recruiting at National Institutes of Health Clinical Center, located at 10 CENTER DR, BLDG. 10 ROOM 2-5940, BETHESDA, MD 20892-0001, phone (301) 496-6353 in Bethesda, Maryland. Active studies at this site cover conditions such as Healthy Volunteers, Breast Cancer and Prostate Cancer. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Bethesda
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Phase 1 Challenge Study Using rDEN2delta30-7169 to Evaluate Host-Pathogen Interactions in Primary, Homotypic, and Heterotypic Dengue Virus Infection
Assessment of [18F]-Fluorocellobiose ([18F]FCB) Pharmacokinetics in Healthy Volunteers and Subjects With Invasive Mold Infections
PET Imaging of Noradrenergic Transmission in the Brain
Natural History of Trisomy 8-Associated Autoinflammatory Disease (TRIAD) and Related Disorders
587 clinical trials at National Institutes of Health Clinical Center
·Clear filters·A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies
Enzalutamide Implants (Enolen) in Patients With Prostate Cancer
Ketoconazole Effects on the Daily Cortisol Rhythm in Mild Autonomous Cortisol Secretion
Evaluation of [11C]ZTP-1 to Image PDE4B
Fibrotic Disease Activity in Cardiopulmonary Disorders Using 18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74) PET/CT Imaging
Partial Stem Cell Transplant for Sickle Cell Disease From Matched Donors
Escalating Doses of VAS-101 in Subjects With Stable Sickle Cell Disease
Tirzepatide s Dopaminergic Effects in Alcohol Use Disorders (AUD)
Safety and Efficacy of PTH-IA
GRAfT 2.0. A Multimodal Prospective Approach to Define the Mechanisms and Clinical Features of Acute and Chronic Rejection in Lung Transplantation
Intravenous Brincidofovir as an Antiviral for Treatment of Progressive Multifocal Leukoencephalopathy: A Pilot Study
Turner Syndrome: Genetic Considerations
NCI Childhood Cancer Data Initiative (CCDI) Led Pediatric, Adolescent, and Young Adult Rare Cancer Registry for Very Rare Solid Tumors
Immune Profiling of CLL/SLL Treated With First-Line Pirtobrutinib
Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma
Natural History of Dysregulation and Aging of the Immune System in People With Trisomy 21 With and Without Thymectomy
Accuracy of 18F-Fluorocholine PET/MR and NeuroEXPLORER PET/CT Imaging for Localization of Parathyroid Tumors
Recombinant Glycosylated Human Interleukin-7 (CYT107) for the Treatment of Kaposi Sarcoma in Participants With HIV and Immune Non-Response (REGIMENKS HIV)
CD22 CAR T-cells to Extend Remission Following Commercial CD19 CAR T-cells in Children, Adolescents, and Adults With Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia
Observational Study of Responses to Treatments in Advanced Central Nervous System (CNS) Tumors
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
THREAT: Testing Harms Related to Exposure to Allergenic and Epithelial Toxins
Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren Disease
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
BPL-1357 Against H1N1 Influenza Virus Challenge
Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis
Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)
Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma
Randomized Stepped Wedge Study of Emapalumab in APECED Enteritis
Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network
Hepatic Lipid Metabolism-Alcohol Use Disorder
Collection of Tissue Samples for Cancer Research
Testing the Combination of the Anti-cancer Drugs ZEN003694 (ZEN-3694) and Talazoparib in Patients With Advanced Solid Tumors, The ComBET Trial
PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)
Phase I Trial Integrating HLA-Haploidentical Anti-CD19 CAR-T Cells With Post-Transplantation Cyclophosphamide-Based HLA-Haploidentical Hematopoietic Cell Transplantation
Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes
Precision-Based Genomics in Prostate Cancer
Testing Atezolizumab With Selinexor in People ≥ 12 Years Old With Alveolar Soft Part Sarcoma, AXIOM Trial
Distinguishing Tics and Functional Tics Using Clinical Neurophysiological Techniques
FAST for DM - Fatty Acid Supplementation Trial (FAST) for Dermatomyositis (DM)
Common conditions studied in Bethesda
- Healthy Volunteers (24 active studies)
- Breast Cancer (19 active studies)
- Prostate Cancer (19 active studies)
- Healthy Volunteer (17 active studies)
- Obesity (15 active studies)
- Neoplasms (14 active studies)
Leading research sponsors in Bethesda
- National Cancer Institute (NCI)
- National Institute of Allergy and Infectious Diseases (NIAID)
- National Heart, Lung, and Blood Institute (NHLBI)
- National Institute of Neurological Disorders and Stroke (NINDS)
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Frequently asked questions
How many paid clinical trials are currently recruiting in Bethesda?
There are approximately 893 recruiting clinical trials in Bethesda, Maryland listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Bethesda pay participants?
Most recruiting trials in Bethesda compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Bethesda?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Bethesda?
The most common conditions under active study in Bethesda include Healthy Volunteers (24), Breast Cancer (19), Prostate Cancer (19), Healthy Volunteer (17), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Bethesda?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Bethesda on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Bethesda?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Bethesda?
Recruiting research sites in Bethesda include National Institutes of Health Clinical Center, Walter Reed National Military Medical Center, National Cancer Institute Developmental Therapeutics Clinic, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Bethesda right now?
The largest active categories in Bethesda are Cancer & tumors (234), Neurology & pain (60), Diabetes & metabolic (25). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of National Institutes of Health Clinical Center?
National Institutes of Health Clinical Center is located at 10 CENTER DR, BLDG. 10 ROOM 2-5940, BETHESDA, MD 20892-0001. Use the Google Maps link in the intro above to get directions.
How do I contact National Institutes of Health Clinical Center?
You can reach National Institutes of Health Clinical Center by phone at (301) 496-6353. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.