Paid Clinical Trials in Birmingham, AL
As of June 2026, 1,066 paid clinical trials are recruiting in Birmingham, Alabama. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Birmingham offers studies at sites including University of Alabama at Birmingham for conditions such as Breast Cancer, Obesity, Sickle Cell Disease, Atopic Dermatitis. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Birmingham
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Birmingham has approximately 1,066 recruiting research studies across a wide range of therapeutic areas. Alabama hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.
Top Research Study Locations in Birmingham
Researchers run research studies in Birmingham, AL at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Alabama at Birmingham | Hypertension, Obesity, Cardiovascular Diseases | 352 |
| University of Alabama at Birmingham Cancer Center | Malignant Solid Neoplasm, Acute Myeloid Leukemia, Recurrent Endometrial Carcinoma | 60 |
| Children's Hospital of Alabama | B Acute Lymphoblastic Leukemia, Malignant Solid Neoplasm, Neuroblastoma | 41 |
| University of Alabama | Chronic Kidney Disease(CKD), Heart Failure, Type 2 DM | 34 |
| University of Alabama Birmingham | Amyotrophic Lateral Sclerosis, AML (Acute Myelogenous Leukemia), Acetabulum Fractures | 32 |
| The University of Alabama at Birmingham | Idiopathic Pulmonary Fibrosis, ALK-positive Histiocytosis, Advanced or Metastatic Solid Tumors | 25 |
| Children's of Alabama | Acute Kidney Injury, Acute Kidney Injury Due to Sepsis, Acute Respiratory Distress Syndrome | 18 |
| UAB | Opioid Overdose, Opioid Use Disorder, Alzheimer Disease | 15 |
| University of Alabama Hospital | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 13 |
| Birmingham VA Medical Center, Birmingham, AL | Adult Growth Hormone Deficiency, Aging, Carcinoma, Hepatocellular | 10 |
| Alabama Oncology | Non-Small Cell Lung Cancer, Cancer, Hormone Receptor Positive HER-2 Negative Breast Cancer | 6 |
| Alabama Clinical Therapeutics | Degenerative Disc Disease, Degenerative Disc Disease (DDD), Gout | 6 |
| Central Alabama Research | Colorectal Cancer, Diabetes, Diabetes Mellitus, Type 2 | 6 |
| University of Alabama - Birmingham | Obstetrical Complications, Cesarean Delivery, High Risk Acute Myeloid Leukemia | 6 |
| University of Alabama at Birmingham (UAB) Hospital | Advanced Systemic Mastocytosis (AdvSM), Aggressive Systemic Mastocytosis (ASM), Antibody-mediated Rejection | 6 |
| AllerVie Clinical Research | Atopic Dermatitis, Allergy, Atopic | 5 |
| Grandview Medical Center | Atrial Fibrillation, Acute Myocardial Infarction (AMI), Atrial Fibrillation (AF) | 5 |
| UAB Lung Health Center | Arsenic and/or Arsenic Compound Adverse Reaction, Chronic Disease, Chronic Obstructive Pulmonary Disease | 5 |
| University of Alabama At Birmingham Hospital | Advanced Solid Tumor, Mantle Cell Lymphoma, B Cell Lymphoma | 5 |
| University of Alabama in Birmingham | Alzheimers Disease, Alzheimers Disease, Familial, Dementia | 5 |
| University of Alabama, Birmingham | Acute Porphyrias, Bone Marrow Transplant (BMT), Breast Cancer | 5 |
| University of Alabama/Children's of Alabama | Neuroblastoma, Ewing Sarcoma, Osteosarcoma | 5 |
| Clinical Trial Site | Acute Hepatic Porphyria, Generalized Myasthenia Gravis, Hereditary Hemorrhagic Telangiectasia | 4 |
| O'Neal Comprehensive Cancer Center at UAB | Advanced Lung Carcinoma, Carcinoma, Endometrial Cancer | 4 |
| Parkway Medical Center | Alcohol Use Disorder, Atherosclerotic Cardiovascular Disease, Atherosclerotic Cardiovascular Disease (ASCVD) | 4 |
Active & Upcoming Studies in Birmingham (2026)
Recruiting trials in Birmingham grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (259 active studies)
- Evaluating Avive+ Soft Tissue Matrix for Prevention of Superficial Radial Nerve Morbidity Following Radial Forearm Free Flap Harvest · University of Alabama at Birmingham
- Mind-Body Group Interventions for Psychological Distress in Young Breast Cancer Survivors · University of Alabama at Birmingham
Cardiovascular (68 active studies)
- Feasibility and Acceptability of Three Component Intervention for the Heart Failure Care for Rural Dwelling Participants · University of Alabama at Birmingham
- Genetic Architecture of Natriuretic Peptides and Blood Pressure Response · University of Alabama at Birmingham
Neurology & pain (65 active studies)
- Behavioral Intervention for Physical Activity and Sexual Dysfunction in Multiple Sclerosis · University of Alabama at Birmingham
- A Study of Ocrelizumab Administered Subcutaneously in Participants With Multiple Sclerosis Who Switch From an Approved Anti-CD20 Therapy · Phase 4 · Genentech, Inc.
Diabetes & metabolic (54 active studies)
- MEDBRIDGE-Guided NCM/CHW Post-Discharge Support for High-Risk T2D Patients · University of Alabama at Birmingham
- VITAL-IMPACT: Improving Cardiometabolic Health in Black Individuals Through Therapeutic Augmentation of Cyclic Guanosine Mono-Phosphate Signaling Pathway · Phase 2 · University of Alabama at Birmingham
HIV / STI (26 active studies)
- Integrating Supports to Promote PrEP for Black Adolescents Working With Apps- Alabama · Emory University
- A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
Pediatric (25 active studies)
- Cue-Based Vs. Clinician-Driven Feeding in Very Low Birthweight Infants · University of Alabama at Birmingham
- Application to Predict Neonatal Apnea With Bradycardia · University of Alabama at Birmingham
Mental health & behavior (19 active studies)
- Online Intervention To Improve Motivation · University of Alabama at Birmingham
- Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression · Phase 3 · VA Office of Research and Development
Vaccines (10 active studies)
- Induction of Cross-protective Antibodies for Serogroup 33 by Pneumococcal Conjugate Vaccines · Phase 4 · University of Alabama at Birmingham
- ME/CFS Brain Fog: Cognitive Rehabilitation Trial · University of Alabama at Birmingham
Eye & vision (5 active studies)
- Intranasal Delivery of Octreotide for Treatment of Diabetic Macular Edema · Phase 1 · University of Alabama at Birmingham
- Integrative Liver-Targeted Therapy for Diabetic Macular Edema: Combining Tauroursodeoxycholate and Traditional Chinese Medicine. · Phase 2 · University of Alabama at Birmingham
Common conditions studied in Birmingham
- Breast Cancer (17 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Obesity (15 active studies). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
- Sickle Cell Disease (13 active studies). Sickle cell disease studies test gene therapies, gene editing, and new small molecules aimed at reducing pain crises and organ damage.
- Atopic Dermatitis (12 active studies). Atopic dermatitis studies test IL-13 inhibitors, JAK inhibitors, and next-generation topical therapies for moderate-to-severe eczema.
- HIV (12 active studies). HIV trials investigate long-acting injectable antiretrovirals, broadly neutralizing antibodies, and cure-focused strategies.
- Hypertension (12 active studies). Hypertension research tests new antihypertensive drug classes, renal denervation devices, and fixed-dose combinations for resistant disease.
Leading research sponsors in Birmingham
- University of Alabama at Birmingham
- National Cancer Institute (NCI)
- Children's Oncology Group
- AstraZeneca
- Novartis Pharmaceuticals
Local regulations and guidelines
Clinical trials in Alabama are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Alabama research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Birmingham. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Birmingham
Hipa.ai aggregates every recruiting study in Birmingham from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Birmingham?
There are approximately 1,066 recruiting clinical trials in Birmingham, Alabama listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Birmingham pay participants?
Most recruiting trials in Birmingham compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Birmingham?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Birmingham?
The most common conditions under active study in Birmingham include Breast Cancer (17), Obesity (15), Sickle Cell Disease (13), Atopic Dermatitis (12), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Birmingham?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Birmingham on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Birmingham?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Birmingham?
Recruiting research sites in Birmingham include University of Alabama at Birmingham, University of Alabama at Birmingham Cancer Center, Children's Hospital of Alabama, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Birmingham right now?
The largest active categories in Birmingham are Cancer & tumors (259), Cardiovascular (68), Neurology & pain (65). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.