Paid Clinical Trials in California

California has 6,346 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 8, 2026.

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5,270 clinical trials

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Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)

for Major Depressive Disorder

Sites in Orange, Long Beach +30 more locations

Sponsor: Autobahn Therapeutics, Inc.

Sex: All·Age: 18 - 65

Code: NCT06633016·Phase 2·Recruiting·Listed Oct 2024

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Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening

for Lung Cancer Diagnosis

Sites in Los Angeles +35 more locations

Sponsor: Freenome Holdings Inc.

Sex: All·Age: 50+

Code: NCT06122077·Recruiting·Listed Nov 2023

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To Evaluate the Safety and Efficacy of MANP in Subjects With Difficult to Control/ Resistant Hypertension

for Difficult to Control Hypertension

Sites in Beverly Hills, Valencia +24 more locations

Sponsor: E-Star BioTech, LLC

Sex: All·Age: 18 - 80

Code: NCT06343298·Phase 2·Recruiting·Listed Apr 2024

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AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM

for Heart Failure

Sites in San Francisco, San Diego +35 more locations

Sponsor: Cordio Medical

Sex: All·Age: 22+

Code: NCT06378632·Recruiting·Listed Apr 2024

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MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions

for In-Stent Restenosis

Sites in Los Angeles +27 more locations

Sponsor: Concept Medical Inc.

Sex: All·Age: 18 - 110

Code: NCT05908331·Recruiting·Listed Jun 2023

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C-Brace Prospective Registry

for Pareses

Sites in San Diego +36 more locations

Sponsor: Otto Bock Healthcare Products GmbH

Sex: All·Age: All ages

Code: NCT04640584·Recruiting·Listed Nov 2020

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ALTO-100 in Bipolar Disorder With Depression (BD-D)

for Bipolar Disorder I or II With a Major Depressive Episode

Sites in Los Angeles, Riverside +22 more locations

Sponsor: Alto Neuroscience

Sex: All·Age: 18 - 70

Code: NCT06656416·Phase 2·Recruiting·Listed Oct 2024

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Impella RP Flex with Smart Assist

for Right Ventricular (RV) Dysfunction

Sites in Los Angeles +30 more locations

Sponsor: Abiomed Inc.

Sex: All·Age: All ages

Code: NCT06637644·Recruiting·Listed Oct 2024

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To Evaluate the Effect of EXPD-101/FXS7553 Compared With Placebo in Patients With COPD Over 52 Weeks of Treatment

for Chronic Obstructive Pulmonary Disease (COPD)

Sites in Northridge +19 more locations

Sponsor: Expedition Therapeutics, Inc

Sex: All·Age: 40 - 85

Code: NCT07684820·Phase 2·Recruiting·Listed Jul 2026

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A Study to Test Whether BI 3034701 Helps People to Lose Weight Who Live With Obesity or Overweight

for Obesity

Sites in West Hills +18 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18 - 74

Code: NCT07662122·Phase 2·Recruiting·Listed Jun 2026

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A Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation

for AML

Sites in Duarte, Stanford +24 more locations

Sponsor: TScan Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07702578·Phase 3·Recruiting·Listed Jul 14, 2026

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A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer

for Pancreatic Ductal Adenocarcinoma (PDAC)

Sites in Los Angeles +23 more locations

Sponsor: Verastem, Inc.

Sex: All·Age: 18+

Code: NCT07644559·Phase 2·Recruiting·Listed Jun 2026

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A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Narcolepsy

for EDS

Sites in Los Angeles, San Francisco +49 more locations

Sponsor: Harmony Biosciences Management, Inc.

Sex: All·Age: 18+

Code: NCT07675135·Phase 3·Recruiting·Listed Jun 2026

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Study of EVO756 in Adults With Migraine

for Migraine

Sites in Los Angeles, Walnut Creek +24 more locations

Sponsor: Evommune, Inc.

Sex: All·Age: 18 - 64

Code: NCT07616128·Phase 2·Recruiting·Listed Jun 2026

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A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High Risk

for Atherosclerosis

Drug: Lepodisiran

Sites in La Jolla, Torrance +15 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 45 - 80

Code: NCT07613294·Phase 3·Recruiting·Listed May 2026

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A Comparative, Randomized, Investigator-blind, Active-controlled, Parallel-group, Multicenter, Clinical Endpoint Study

for Primary Open Angle Glaucoma (POAG)

Sites in Newport Beach, Beverly Hills +14 more locations

Sponsor: YS Life Science Co., Ltd.

Sex: All·Age: 18+

Code: NCT07661329·Phase 3·Recruiting·Listed Jun 2026

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Trial Comparing the Safety and Efficacy of Two Different Oral VPV Doses With Placebo as Treatment for RV in Participants With COPD

for Rhinovirus Infection

Sites in San Diego, Newport Beach +32 more locations

Sponsor: Altesa Biosciences, Inc.

Sex: All·Age: 40 - 85

Code: NCT07610395·Phase 2·Recruiting·Listed May 2026

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A Study to Assess the Safety and Effects of ABBV-1758 Following Subcutaneous or Intravenous Injections in Participants With Alzheimer's Disease

for Alzheimer's Disease

Sites in Irvine +10 more locations

Sponsor: AbbVie

Sex: All·Age: 50 - 90

Code: NCT07599670·Phase 1, Phase 2·Recruiting·Listed May 2026

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A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With Obesity

for Obesity

Drug: NNC0662-0419

Sites in Los Angeles, Costa Mesa +22 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07639021·Phase 2·Recruiting·Listed Jun 2026

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A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity

for Obesity

Sites in Sacramento, Walnut Creek +32 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07595549·Phase 3·Recruiting·Listed May 2026

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PRESERVE: LUPKYNIS in Combination With Belimumab, Obinutuzumab or Anifrolumab in Patients With Lupus Nephritis

for Lupus Nephritis

Sites in Los Alamitos, La Mesa +25 more locations

Sponsor: Aurinia Pharmaceuticals Inc.

Sex: All·Age: 18 - 75

Code: NCT07611214·Phase 4·Recruiting·Listed May 2026

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Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

for Pancreatic Cancer

Drug: Atebimetinib

Sites in Duarte +37 more locations

Sponsor: Immuneering Corporation

Sex: All·Age: 18+

Code: NCT07562152·Phase 3·Recruiting·Listed May 2026

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A Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Major Depressive Disorder

for Depressive Disorder, Major

Drug: Seltorexant

Sites in Orange, Walnut Creek +29 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18 - 74

Code: NCT07573176·Phase 3·Recruiting·Listed May 2026

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Surabgene Lomparvovec Administered in the Suprachoroidal Space in Adult Participants With Diabetic Retinopathy Without Center-Involved Diabetic Macular Edema

for Diabetic Retinopathy

Drug: Surabgene Lomparvovec

Sites in San Francisco, Torrance +27 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07592273·Phase 2, Phase 3·Recruiting·Listed May 2026

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A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC PFS in Adult Participants With Graves' Disease

for Graves' Disease

Drug: Efgartigimod PH20 SC

Sites in Orange, Pasadena +15 more locations

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT07570316·Phase 3·Recruiting·Listed May 2026

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Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)

for Urothelial Cancer

Sites in Santa Barbara +11 more locations

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT07566156·Phase 3·Recruiting·Listed May 2026

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A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions and Subcutaneous Injections of ABBV-519 in Adult Participants With Systemic Lupus Erythematosus (SLE) or Rheumatoid Arthritis (RA)

for Systemic Lupus Erythematosus

Sites in Tustin +8 more locations

Sponsor: AbbVie

Sex: All·Age: 18 - 75

Code: NCT07607964·Phase 1·Recruiting·Listed May 2026

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Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System

for Type 2 Diabetes Mellitus

Sites in Los Angeles, Santa Barbara +9 more locations

Sponsor: Insulet Corporation

Sex: All·Age: 14 - 75

Code: NCT07579702·Recruiting·Listed May 2026

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Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events

for Obesity

Sites in Walnut Creek +10 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07607587·Phase 1·Recruiting·Listed May 2026

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A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Constipation (IBS-C)

for Irritable Bowel Syndrome

Drug: Brenipatide

Sites in Anaheim, Lancaster +12 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT07545772·Phase 2·Recruiting·Listed Apr 2026

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A Study of LY4005130 in Adult Participants With Non-Segmental Vitiligo

for Vitiligo

Drug: LY4005130

Sites in Fremont, Northridge +16 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT07533019·Phase 2·Recruiting·Listed Apr 2026

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A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Diarrhea (IBS-D)

for Irritable Bowel Syndrome

Drug: Brenipatide

Sites in Anaheim, Lancaster +13 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT07545759·Phase 2·Recruiting·Listed Apr 2026

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AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea

for Obesity

Drug: NNC0487-0111

Sites in San Diego +16 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07571005·Phase 3·Recruiting·Listed May 2026

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A Phase 2 Trial of Dotinurad in Xanthine Oxidase Inhibitor (XOI) Intolerant/Uricase Failure Gout Participants

for Gout

Drug: Dotinurad

Sites in Thousand Oaks, Tustin +36 more locations

Sponsor: Crystalys Therapeutics

Sex: All·Age: 18 - 75

Code: NCT07535034·Phase 2·Recruiting·Listed Apr 2026

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AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

for Diabetes Mellitus

Drug: NNC0487-0111

Sites in Walnut Creek, Lomita +12 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07533175·Phase 3·Recruiting·Listed Apr 2026

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A Clinical Study Evaluating Licaminlimab for Dry Eye Disease

for Dry Eye Disease (DED)

Sites in Newport Beach, Glendale +10 more locations

Sponsor: Oculis

Sex: All·Age: 18+

Code: NCT07548632·Phase 2, Phase 3·Recruiting·Listed Apr 2026

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A Study Comparing JNJ-79635322 and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

Drug: Teclistamab

Sites in Los Angeles, Orange +33 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07518186·Phase 3·Recruiting·Listed Apr 2026

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A Study of VARIPULSE Pulsed Field Ablation (PFA) Catheter and FARAWAVE PFA Catheter in the Treatment of Participants With Persistent Atrial Fibrillation

for Atrial Fibrillation

Sites in Stanford, Fountain Valley +28 more locations

Sponsor: Biosense Webster, Inc.

Sex: All·Age: 18 - 80

Code: NCT07523750·Recruiting·Listed Apr 2026

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A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)

for Alpha 1 Antitrypsin Deficiency

Sites in Los Angelas +9 more locations

Sponsor: Grifols Therapeutics LLC

Sex: All·Age: 18 - 80

Code: NCT07555483·Phase 3·Recruiting·Listed Apr 2026

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Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes

for Type 2 Diabetes Mellitus

Sites in Los Angeles, Newport Beach +24 more locations

Sponsor: Insulet Corporation

Sex: All·Age: 18 - 75

Code: NCT07521475·Recruiting·Listed Apr 2026

Apply to this trial