Paid Clinical Trials in California

California has 6,346 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 8, 2026.

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5,270 clinical trials

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AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

for Obesity

Drug: NNC0487-0111

Sites in Lancaster, Escondido +17 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07509307·Phase 3·Recruiting·Listed Apr 2026

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A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Idiopathic Hypersomnia (IH)

for Idiopathic Hypersomnia

Sites in Santa Monica, Redwood City +38 more locations

Sponsor: Harmony Biosciences Management, Inc.

Sex: All·Age: 18+

Code: NCT07500090·Phase 3·Recruiting·Listed Mar 2026

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BGB-43395 Plus Letrozole Versus CDK4/6i Plus Letrozole for Patients With Advanced or Metastatic HR+/HER2- Breast Cancer Who Have Not Received Prior Treatment for Advanced or Metastatic Disease

for HR+/HER2- Breast Cancer

Sites in Fountain Valley, Oxnard +34 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT07492641·Phase 3·Recruiting·Listed Mar 2026

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Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

for Pancreatic Cancer

Drug: daraxonrasib

Sites in San Francisco +12 more locations

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT07491445·Phase 3·Recruiting·Listed Mar 2026

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A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's Disease

for Colitis, Ulcerative

Sites in Los Angeles, Oxnard +11 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 80

Code: NCT07483073·Phase 2·Recruiting·Listed Mar 2026

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A Study of LY4395089 and Mirikizumab (LY3074828) Given Together and Mirikizumab (Alone) in Adults With Crohn's Disease

for Crohn Disease

Drug: LY4395089

Sites in Los Angeles, Oxnard +12 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 80

Code: NCT07483099·Phase 2·Recruiting·Listed Mar 2026

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Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015)

for Psoriatic Arthritis

Drug: Tulisokibart

Sites in Riverside, Thousand Oaks +16 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18 - 80

Code: NCT07486960·Phase 2·Recruiting·Listed Mar 2026

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RE104 Safety and Efficacy Study in Generalized Anxiety Disorder

for Generalized Anxiety Disorder

Sites in San Francisco, La Jolla +26 more locations

Sponsor: Reunion Neuroscience Inc

Sex: All·Age: 18 - 74

Code: NCT07489651·Phase 2·Recruiting·Listed Mar 2026

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Continuous Dual Aspiration Technique With Zoom System for Stroke

for Ischemic Stroke

Sites in Walnut Creek +16 more locations

Sponsor: Imperative Care, Inc.

Sex: All·Age: 18+

Code: NCT07491952·Recruiting·Listed Mar 2026

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An Efficacy and Safety Study of Cenegermin Ophthalmic Solution Compared With Vehicle in the Treatment of PCED

for Persistent Corneal Epithelial Defect

Sites in Los Angeles, Loma Linda +16 more locations

Sponsor: Dompé Farmaceutici S.p.A

Sex: All·Age: 18+

Code: NCT07519902·Phase 3·Recruiting·Listed Apr 2026

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A Phase 1/2 Study of TRI-611 in ALK-Positive NSCLC

for ALK-positive NSCLC

Sites in San Francisco +13 more locations

Sponsor: TRIANA Biomedicines, Inc.

Sex: All·Age: 18+

Code: NCT07491497·Phase 1, Phase 2·Recruiting·Listed Mar 2026

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A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors

for Gastric or Gastro-esophageal Junction (GEJ) Adenocarcinoma

Sites in Los Angeles +13 more locations

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT07488676·Phase 1, Phase 2·Recruiting·Listed Mar 2026

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A Phase 2 Study to Evaluate Povetacicept in Adults With Generalized Myasthenia Gravis

for Myasthenia Gravis, Generalized

Sites in Mission Hills +14 more locations

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18+

Code: NCT07501702·Phase 2·Recruiting·Listed Mar 2026

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FOLFIRI and Bevacizumab With or Without Pelareorep for Second-Line Treatment of Metastatic RAS-Mutated, Microsatellite-Stable Colorectal Cancer

for Ras-mutated Metastatic Colorectal Cancer

Drug: Bevacizumab

Sites in Los Angeles, Beverly Hills +11 more locations

Sponsor: Oncolytics Biotech

Sex: All·Age: 18+

Code: NCT07446322·Phase 2·Recruiting·Listed Mar 2026

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Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Mellitus Who Are Not Achieving Glycemic Targets While Using GLP-1-Based Therapy

for Type 2 Diabetes

Sites in San Diego, Long Beach +15 more locations

Sponsor: Biomea Fusion Inc.

Sex: All·Age: 18 - 70

Code: NCT07502508·Phase 2·Recruiting·Listed Mar 2026

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A Study to Investigate Efficacy and Safety of FWY003 Compared With Placebo in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration

for Geographic Atrophy Secondary to Age-related Macular Degeneration

Drug: FWY003

Sites in Sacramento, Huntington Beach +13 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 50+

Code: NCT07441642·Phase 2·Recruiting·Listed Mar 2026

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An Exploratory Efficacy and Safety Study of DFL24498 Topical Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease

for Dry Eye Disease (DED)

Sites in Newport Beach, Torrance +22 more locations

Sponsor: Dompé Farmaceutici S.p.A

Sex: All·Age: 18+

Code: NCT07503886·Phase 2·Recruiting·Listed Mar 2026

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A Study to Develop a Blood-based Test for Aiding the Diagnosis/Prognosis of Traumatic Brain Injury in Adults and for Monitoring the Development of Secondary Events in Patients Diagnosed With Traumatic Brain Injury

for Traumatic Brain Injury

Sites in San Francisco, Sacramento +11 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07455136·Recruiting·Listed Mar 2026

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A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

for Obesity

Drug: NNC0487-0111

Sites in Walnut Creek +18 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07481630·Phase 3·Recruiting·Listed Mar 2026

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A Study of MUC16-Directed Antibody Drug Conjugate HWK-016 in Participants With Advanced Solid Tumors.

for PROC

Sites in Los Angeles +11 more locations

Sponsor: Whitehawk Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07470853·Phase 1·Recruiting·Listed Mar 2026

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Study Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid Tumors

for Endometrial Cancer

Sites in Los Angeles +11 more locations

Sponsor: Whitehawk Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07444814·Phase 1·Recruiting·Listed Mar 2026

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A Solid Tumor Study for Long Term Treatment of Cancer Patients Who Participated in Adagrasib Studies

for Solid Tumors

Drug: Adagrasib

Sites in Long Beach, Bellflower +12 more locations

Sponsor: Mirati Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT07415031·Phase 2·Recruiting·Listed Feb 2026

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A Phase IIb Dose-ranging Study to Assess the Efficacy and Safety of GIA632 in Participants With Non-segmental Vitiligo

for Non-segmental Vitiligo

Drug: GIA632

Sites in San Diego, Fountain Valley +19 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 99

Code: NCT07431177·Phase 2·Recruiting·Listed Feb 2026

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Immune Modulation During Palynziq® Treatment in Adults (IMPALA)

for Phenylketonuria

Sites in Los Angeles +11 more locations

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 18 - 65

Code: NCT07477691·Phase 4·Recruiting·Listed Mar 2026

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A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes

for Diabetes Mellitus, Type 2

Drug: NNC0662-0419

Sites in San Diego, Long Beach +21 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18 - 75

Code: NCT07415954·Phase 2·Recruiting·Listed Feb 2026

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A Study to Learn How Stargardt-type Eye Conditions Progress in Children and Adults

for Stargardt Disease

Sites in Palo Alto, Sacramento +13 more locations

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 6+

Code: NCT07425574·Recruiting·Listed Feb 2026

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A Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

for Myelodysplastic Syndrome

Sites in Duarte, Santa Rosa +23 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07422480·Phase 3·Recruiting·Listed Feb 2026

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A Study to Assess the Safety and Efficacy of Different Doses of ELV001 to Treat Active Rheumatoid Arthritis in Patients With an Inadequate Response to Methotrexate and Tumor Necrosis Factor Inhibition (START SYNERGY)

for Active Rheumatoid Arthritis

Sites in Tustin +21 more locations

Sponsor: Elevara Medicines Limited

Sex: All·Age: 18 - 75

Code: NCT07409103·Phase 2·Recruiting·Listed Feb 2026

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A Study to Evaluate D-2570 in Participants With Moderate to Severe Plaque Psoriasis

for Psoriasis

Sites in Los Angeles, San Diego +18 more locations

Sponsor: InventisBio Co., Ltd

Sex: All·Age: 18 - 70

Code: NCT07489885·Phase 2·Recruiting·Listed Mar 2026

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A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events

for Atherosclerosis

Sites in Irvine, Beverly Hills +21 more locations

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT07448038·Phase 2·Recruiting·Listed Mar 2026

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Study of INCA036978 in Participants With Myeloproliferative Neoplasms

for Myeloproliferative Neoplasms

Drug: INCA036978

Sites in Los Angeles, Irvine +21 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07441694·Phase 1·Recruiting·Listed Mar 2026

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A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME)

for Diabetic Macular Edema

Drug: RO7823653

Sites in Walnut Creek, Beverly Hills +10 more locations

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT07425522·Phase 1·Recruiting·Listed Feb 2026

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A Trial to Evaluate Efficacy and Safety of Maridebart Cafraglutide in Adults Living With Elevated Liver Fat and Obesity or Overweight

for Overweight or Obesity and Elevated Liver Fat

Sites in San Diego, Escondido +21 more locations

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07441252·Phase 2·Recruiting·Listed Feb 2026

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A Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the Treatment of Schizophrenia and Autism-Related Irritability in Adolescents, Respectively

for Schizophrenia

Drug: KarXT

Sites in Los Angeles, San Francisco +47 more locations

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All·Age: 5 - 17

Code: NCT07424404·Phase 3·Recruiting·Listed Feb 2026

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A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight

for Sleep Apnea, Obstructive

Drug: Eloralintide

Sites in Long Beach, Riverside +21 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07369011·Phase 3·Recruiting·Listed Jan 2026

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Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable

for Atrial Fibrillation (AF)

Sites in Pasadena, Fremont +16 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07430956·Phase 3·Recruiting·Listed Feb 2026

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Study of GB-4362 With Enfortumab Vedotin and Pembrolizumab for Advanced Urothelial Cancer

for Advanced Urothelial Cancer

Sites in Duarte, Irvine +8 more locations

Sponsor: Generate Biomedicines

Sex: All·Age: 18+

Code: NCT07484022·Phase 1·Recruiting·Listed Mar 2026

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Phase 3 Extension Study of ADX-324 in Participants With Hereditary Angioedema (HAE)

for Hereditary Angioedema (HAE)

Sites in San Diego, Walnut Creek +13 more locations

Sponsor: ADARx Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07428499·Phase 3·Recruiting·Listed Feb 2026

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Efficacy and Safety of Intranasal Cenegermin in Adult Participants With Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)

for Non-Arteritic Anterior Ischemic Optic Neuropathy

Sites in Los Angeles, Newport Beach +16 more locations

Sponsor: Dompé Farmaceutici S.p.A

Sex: All·Age: 50 - 80

Code: NCT07453888·Phase 3·Recruiting·Listed Mar 2026

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A Study to Evaluate the Efficacy and Safety of Veverimer for the Treatment of Metabolic Acidosis

for CKD

Sites in Los Angeles, San Diego +21 more locations

Sponsor: Renibus Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07355062·Phase 3·Recruiting·Listed Jan 2026

Apply to this trial