Paid Clinical Trials in California

California has 6,389 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 25, 2026.

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5,286 clinical trials

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Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)

for Urothelial Cancer

Sites in Santa Barbara +10 more locations

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT07566156·Phase 3·Recruiting·Listed May 2026

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Surabgene Lomparvovec Administered in the Suprachoroidal Space in Adult Participants With Diabetic Retinopathy Without Center-Involved Diabetic Macular Edema

for Diabetic Retinopathy

Drug: Surabgene Lomparvovec

Sites in Torrance, Pasadena +12 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07592273·Phase 2, Phase 3·Recruiting·Listed May 2026

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PRESERVE: LUPKYNIS in Combination With Belimumab, Obinutuzumab or Anifrolumab in Patients With Lupus Nephritis

for Lupus Nephritis

Sites in Los Alamitos, La Mesa +13 more locations

Sponsor: Aurinia Pharmaceuticals Inc.

Sex: All·Age: 18 - 75

Code: NCT07611214·Phase 4·Recruiting·Listed May 28, 2026

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Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System

for Type 2 Diabetes Mellitus

Sites in Los Angeles, Santa Barbara +10 more locations

Sponsor: Insulet Corporation

Sex: All·Age: 14 - 75

Code: NCT07579702·Recruiting·Listed May 2026

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AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea

for Obesity

Drug: NNC0487-0111

Sites in San Diego +16 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07571005·Phase 3·Recruiting·Listed May 2026

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A Study of LY4005130 in Adult Participants With Non-Segmental Vitiligo

for Vitiligo

Drug: LY4005130

Sites in Fremont, Northridge +16 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT07533019·Phase 2·Recruiting·Listed Apr 2026

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A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Constipation (IBS-C)

for Irritable Bowel Syndrome

Drug: Brenipatide

Sites in Anaheim, Los Alamitos +12 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT07545772·Phase 2·Recruiting·Listed Apr 2026

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A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Diarrhea (IBS-D)

for Irritable Bowel Syndrome

Drug: Brenipatide

Sites in Anaheim, Los Alamitos +13 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT07545759·Phase 2·Recruiting·Listed Apr 2026

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AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

for Diabetes Mellitus

Drug: NNC0487-0111

Sites in Walnut Creek, Escondido +13 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07533175·Phase 3·Recruiting·Listed Apr 2026

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A Clinical Study Evaluating Licaminlimab for Dry Eye Disease

for Dry Eye Disease (DED)

Sites in Newport Beach, Glendale +12 more locations

Sponsor: Oculis

Sex: All·Age: 18+

Code: NCT07548632·Phase 2, Phase 3·Recruiting·Listed Apr 2026

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A Phase 2 Trial of Dotinurad in Xanthine Oxidase Inhibitor (XOI) Intolerant/Uricase Failure Gout Participants

for Gout

Drug: Dotinurad

Sites in Thousand Oaks, Granada Hills +15 more locations

Sponsor: Crystalys Therapeutics

Sex: All·Age: 18 - 75

Code: NCT07535034·Phase 2·Recruiting·Listed Apr 2026

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A Study Comparing JNJ-79635322 and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

Drug: Teclistamab

Sites in Los Angeles +10 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07518186·Phase 3·Recruiting·Listed Apr 2026

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Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes

for Type 2 Diabetes Mellitus

Sites in Santa Barbara, Vallejo +17 more locations

Sponsor: Insulet Corporation

Sex: All·Age: 18 - 75

Code: NCT07521475·Recruiting·Listed Apr 2026

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A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)

for Alpha 1 Antitrypsin Deficiency

Sites in Los Angelas +9 more locations

Sponsor: Grifols Therapeutics LLC

Sex: All·Age: 18 - 80

Code: NCT07555483·Phase 3·Recruiting·Listed Apr 2026

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A Study of VARIPULSE Catheter in Participants With Persistent Atrial Fibrillation Undergoing Pulmonary Vein and Superior Vena Cava Isolation

for Atrial Fibrillation

Sites in Santa Monica, Larkspur +16 more locations

Sponsor: Biosense Webster, Inc.

Sex: All·Age: 18 - 80

Code: NCT07527299·Recruiting·Listed Apr 2026

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AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

for Obesity

Drug: NNC0487-0111

Sites in Lancaster, Escondido +17 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07509307·Phase 3·Recruiting·Listed Apr 2026

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An Efficacy and Safety Study of Cenegermin Ophthalmic Solution Compared With Vehicle in the Treatment of PCED

for Persistent Corneal Epithelial Defect

Sites in Los Angeles, Loma Linda +16 more locations

Sponsor: Dompé Farmaceutici S.p.A

Sex: All·Age: 18+

Code: NCT07519902·Phase 3·Recruiting·Listed Apr 2026

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A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Idiopathic Hypersomnia (IH)

for Idiopathic Hypersomnia

Sites in Santa Monica, Redwood City +20 more locations

Sponsor: Harmony Biosciences Management, Inc.

Sex: All·Age: 18+

Code: NCT07500090·Phase 3·Recruiting·Listed Mar 2026

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Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Mellitus Who Are Not Achieving Glycemic Targets While Using GLP-1-Based Therapy

for Type 2 Diabetes

Sites in San Diego, Long Beach +15 more locations

Sponsor: Biomea Fusion Inc.

Sex: All·Age: 18 - 70

Code: NCT07502508·Phase 2·Recruiting·Listed Mar 2026

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BGB-43395 Plus Letrozole Versus CDK4/6i Plus Letrozole for Patients With Advanced or Metastatic HR+/HER2- Breast Cancer Who Have Not Received Prior Treatment for Advanced or Metastatic Disease

for HR+/HER2- Breast Cancer

Sites in Fountain Valley +24 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT07492641·Phase 3·Recruiting·Listed Mar 2026

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Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015)

for Psoriatic Arthritis

Drug: Tulisokibart

Sites in Riverside, Thousand Oaks +14 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18 - 80

Code: NCT07486960·Phase 2·Recruiting·Listed Mar 2026

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A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's Disease

for Colitis, Ulcerative

Sites in Los Angeles, Oxnard +13 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 80

Code: NCT07483073·Phase 2·Recruiting·Listed Mar 2026

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A Study of LY4395089 and Mirikizumab (LY3074828) Given Together and Mirikizumab (Alone) in Adults With Crohn's Disease

for Crohn Disease

Drug: LY4395089

Sites in Los Angeles, Oxnard +13 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 80

Code: NCT07483099·Phase 2·Recruiting·Listed Mar 2026

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An Exploratory Efficacy and Safety Study of DFL24498 Topical Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease

for Dry Eye Disease (DED)

Sites in Newport Beach, Torrance +22 more locations

Sponsor: Dompé Farmaceutici S.p.A

Sex: All·Age: 18+

Code: NCT07503886·Phase 2·Recruiting·Listed Mar 2026

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RE104 Safety and Efficacy Study in Generalized Anxiety Disorder

for Generalized Anxiety Disorder

Sites in San Francisco, La Jolla +20 more locations

Sponsor: Reunion Neuroscience Inc

Sex: All·Age: 18 - 74

Code: NCT07489651·Phase 2·Recruiting·Listed Mar 2026

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Continuous Dual Aspiration Technique With Zoom System for Stroke

for Ischemic Stroke

Sites in Walnut Creek +15 more locations

Sponsor: Imperative Care, Inc.

Sex: All·Age: 18+

Code: NCT07491952·Recruiting·Listed Mar 2026

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AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss

for Obesity

Drug: NNC0487-0111

Sites in Walnut Creek +12 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07503210·Phase 3·Recruiting·Listed Mar 2026

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A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

for Obesity

Drug: NNC0487-0111

Sites in Walnut Creek +18 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07481630·Phase 3·Recruiting·Listed Mar 2026

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A Phase 1/2 Study of TRI-611 in ALK-Positive NSCLC

for ALK-positive NSCLC

Sites in San Francisco +10 more locations

Sponsor: TRIANA Biomedicines, Inc.

Sex: All·Age: 18+

Code: NCT07491497·Phase 1, Phase 2·Recruiting·Listed Mar 2026

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Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Who Are Not Achieving Glycemic Targets

for Type 2 Diabetes

Sites in San Diego, Long Beach +14 more locations

Sponsor: Biomea Fusion Inc.

Sex: All·Age: 18 - 70

Code: NCT07502495·Phase 2·Recruiting·Listed Mar 2026

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A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors

for Gastric or Gastro-esophageal Junction (GEJ) Adenocarcinoma

Sites in Los Angeles +10 more locations

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT07488676·Phase 1, Phase 2·Recruiting·Listed Mar 2026

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Immune Modulation During Palynziq® Treatment in Adults (IMPALA)

for Phenylketonuria

Sites in Los Angeles +11 more locations

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 18 - 65

Code: NCT07477691·Phase 4·Recruiting·Listed Mar 2026

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FOLFIRI and Bevacizumab With or Without Pelareorep for Second-Line Treatment of Metastatic RAS-Mutated, Microsatellite-Stable Colorectal Cancer

for Ras-mutated Metastatic Colorectal Cancer

Drug: Bevacizumab

Sites in Los Angeles, Beverly Hills +11 more locations

Sponsor: Oncolytics Biotech

Sex: All·Age: 18+

Code: NCT07446322·Phase 2·Recruiting·Listed Mar 2026

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A Study to Investigate Efficacy and Safety of FWY003 Compared With Placebo in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration

for Geographic Atrophy Secondary to Age-related Macular Degeneration

Drug: FWY003

Sites in Sacramento, Huntington Beach +13 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 50+

Code: NCT07441642·Phase 2·Recruiting·Listed Mar 2026

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A Study to Develop a Blood-based Test for Aiding the Diagnosis/Prognosis of Traumatic Brain Injury in Adults and for Monitoring the Development of Secondary Events in Patients Diagnosed With Traumatic Brain Injury

for Traumatic Brain Injury

Sites in San Francisco, Sacramento +10 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07455136·Recruiting·Listed Mar 2026

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A Study to Evaluate D-2570 in Participants With Moderate to Severe Plaque Psoriasis

for Psoriasis

Sites in Los Angeles, San Diego +18 more locations

Sponsor: InventisBio Co., Ltd

Sex: All·Age: 18 - 70

Code: NCT07489885·Phase 2·Recruiting·Listed Mar 2026

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A Trial to Evaluate Efficacy and Safety of Maridebart Cafraglutide in Adults Living With Elevated Liver Fat and Obesity or Overweight

for Overweight or Obesity and Elevated Liver Fat

Sites in San Diego, Canoga Park +21 more locations

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07441252·Phase 2·Recruiting·Listed Feb 2026

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A Study of mRNA-1018-H5 Pandemic Influenza Vaccine in Healthy Adults

for Influenza

Sites in San Bernardino +9 more locations

Sponsor: ModernaTX, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07496450·Phase 3·Recruiting·Listed Mar 2026

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A Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

for Myelodysplastic Syndrome

Sites in Duarte, Santa Rosa +23 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07422480·Phase 3·Recruiting·Listed Feb 2026

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A Study to Assess the Safety and Efficacy of Different Doses of ELV001 to Treat Active Rheumatoid Arthritis in Patients With an Inadequate Response to Methotrexate and Tumor Necrosis Factor Inhibition (START SYNERGY)

for Active Rheumatoid Arthritis

Sites in Tustin +21 more locations

Sponsor: Elevara Medicines Limited

Sex: All·Age: 18 - 75

Code: NCT07409103·Phase 2·Recruiting·Listed Feb 2026

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