Paid Clinical Trials in California

California has 6,346 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 8, 2026.

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5,270 clinical trials

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KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GIST in 1st Line Setting (SynerGIST-1st Line)

for GIST - Gastrointestinal Stromal Tumor

Sites in Los Angeles +16 more locations

Sponsor: Kumquat Biosciences Inc.

Sex: All·Age: 18+

Code: NCT07406633·Phase 2·Recruiting·Listed Feb 2026

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A Study to Evaluate the Efficacy and Safety of E2086 in Adults With Narcolepsy

for Narcolepsy

Sites in Santa Ana +16 more locations

Sponsor: Eisai Inc.

Sex: All·Age: 18+

Code: NCT07493265·Phase 2·Recruiting·Listed Mar 2026

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Study to Evaluate LB-102 for the Treatment of Adult Patients With Acute Schizophrenia

for Schizophrenia

Sites in Riverside, Garden Grove +11 more locations

Sponsor: LB Pharmaceuticals Inc.

Sex: All·Age: 18 - 65

Code: NCT07363577·Phase 3·Recruiting·Listed Jan 2026

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A Study of TAK-505 in Adults With Solid Tumors

for Malignant Solid Tumors

Sites in San Francisco, San Diego +13 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07436728·Phase 1, Phase 2·Recruiting·Listed Feb 2026

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A Study to Learn About mRNA Vaccines Against Influenza in Adults

for Healthy Adults

Sites in Walnut Creek +14 more locations

Sponsor: Pfizer

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07431853·Phase 2·Recruiting·Listed Feb 2026

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Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis

for Knee Cartilage Defects

Sites in La Jolla, Santa Monica +26 more locations

Sponsor: Medipost, Inc.

Sex: All·Age: 18 - 75

Code: NCT07339111·Phase 3·Recruiting·Listed Jan 2026

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Study to Evaluate Resmetirom in Post-Liver Transplant Patients With MASH

for MASH - Metabolic Dysfunction-Associated Steatohepatitis

Sites in Los Angeles, San Francisco +14 more locations

Sponsor: Madrigal Pharmaceuticals, Inc.

Sex: All·Age: 18 - 75

Code: NCT07335601·Phase 2·Recruiting·Listed Jan 2026

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Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

for Glioblastoma (GBM)

Sites in Los Angeles, Palo Alto +27 more locations

Sponsor: Black Diamond Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07326566·Phase 2·Recruiting·Listed Jan 2026

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Study of DISC-0974-201 in Participants With IBD and Anemia

for Inflammatory Bowel Disease (IBD)

Sites in Los Angeles +13 more locations

Sponsor: Disc Medicine, Inc

Sex: All·Age: 18+

Code: NCT07368972·Phase 2·Recruiting·Listed Jan 2026

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A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1)

for Bipolar Disorder

Drug: Brenipatide

Sites in Orange +19 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT07286175·Phase 2·Recruiting·Listed Dec 2025

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A Study to Evaluate the Efficacy and Safety of JNJ-88545223 for the Treatment of Participants With Active Psoriatic Arthritis

for Arthritis, Psoriatic

Sites in San Diego, Huntington Beach +14 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07321873·Phase 2·Recruiting·Listed Jan 2026

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Non-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous Administration in Adult Participants With Multiple Sclerosis

for Multiple Sclerosis

Drug: Frexalimab

Sites in West Hollywood +21 more locations

Sponsor: Sanofi

Sex: All·Age: 18 - 60

Code: NCT07325292·Phase 3·Recruiting·Listed Jan 2026

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Efficacy and Safety of Vamifeport in Adult Participants With Homeostatic Iron Regulator Gene (HFE)-Related Hereditary Hemochromatosis

for Homeostatic Iron Regulator Gene-related Hereditary Hemochromatosis

Drug: Vamifeport

Sites in San Diego +18 more locations

Sponsor: CSL Behring

Sex: All·Age: 18+

Code: NCT07332091·Phase 2·Recruiting·Listed Jan 2026

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A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease

for Systemic Lupus Erythematosus (SLE)

Drug: Enpatoran

Sites in Los Angeles, Thousand Oaks +10 more locations

Sponsor: EMD Serono Research & Development Institute, Inc.

Sex: All·Age: 18 - 75

Code: NCT07332481·Phase 3·Recruiting·Listed Jan 2026

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Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors

for Melanoma (Skin Cancer)

Sites in Los Angeles, San Francisco +18 more locations

Sponsor: Aminex Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07287917·Phase 1, Phase 2·Recruiting·Listed Dec 2025

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A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease

for Huntington Disease

Sites in Sacramento, La Jolla +32 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 21 - 70

Code: NCT07326709·Phase 3·Recruiting·Listed Jan 2026

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A Study to Assess Real-World Use and Outcomes of TAR-200 for Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) in the United States

for Non-Muscle Invasive Bladder Neoplasms

Sites in Los Angeles +16 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07309445·Recruiting·Listed Dec 2025

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Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI)

for Coronary Artery Disease

Sites in Sacramento, Loma Linda +17 more locations

Sponsor: Supira Medical

Sex: All·Age: 18 - 90

Code: NCT07296744·Recruiting·Listed Dec 2025

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Phase 2 Study of Kylo-11 in ASCVD Patients With Elevated Lp(a)

for Lipoprotein Disorder

Sites in Los Angeles, San Diego +14 more locations

Sponsor: Kylonova (Xiamen) Biopharma co., LTD.

Sex: All·Age: 18 - 80

Code: NCT07327840·Phase 2·Recruiting·Listed Jan 2026

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Study to Assess the Efficacy and Safety of Rina-S in Participants With Non-small Cell Lung Cancer

for Non-small Cell Lung Cancer (NSCLC)

Sites in San Diego, Santa Rosa +17 more locations

Sponsor: Genmab

Sex: All·Age: 18+

Code: NCT07288177·Phase 2·Recruiting·Listed Dec 2025

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CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

for Locally Advanced / Metastatic Solid Tumors

Sites in Los Angeles +14 more locations

Sponsor: Crescent Biopharma, Inc.

Sex: All·Age: 18+

Code: NCT07335497·Phase 1, Phase 2·Recruiting·Listed Jan 2026

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ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

for Major Depressive Disorder (MDD)

Sites in La Jolla, Orange +20 more locations

Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All·Age: 18 - 65

Code: NCT07284667·Phase 2·Recruiting·Listed Dec 2025

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A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

for NSCLC Adenocarcinoma

Sites in Santa Rosa +16 more locations

Sponsor: IDEAYA Biosciences

Sex: All·Age: 18+

Code: NCT07277413·Phase 1·Recruiting·Listed Dec 2025

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A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)

for Ovarian Neoplasms

Sites in Walnut Creek +25 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: Female·Age: 18+

Code: NCT07318558·Phase 3·Recruiting·Listed Jan 2026

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Pridopidine Phase 3 Study to Evaluate Efficacy and Safety in ALS

for Amyotrophic Lateral Sclerosis

Sites in San Francisco +17 more locations

Sponsor: Prilenia

Sex: All·Age: 18 - 80

Code: NCT07322003·Phase 3·Recruiting·Listed Jan 2026

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A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-2)

for Severe Asthma

Sites in Lancaster, Bakersfield +17 more locations

Sponsor: Generate Biomedicines

Sex: All·Age: 12 - 80

Code: NCT07359846·Phase 3·Recruiting·Listed Jan 2026

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ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis

for Myasthenia Gravis

Sites in Carlsbad +11 more locations

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT07294170·Recruiting·Listed Dec 2025

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Efficacy, Safety, and Tolerability of NBI-1065890 Versus Placebo in Adults With Tardive Dyskinesia

for Tardive Dyskinesia

Sites in Long Beach, Torrance +16 more locations

Sponsor: Neurocrine Biosciences

Sex: All·Age: 18 - 75

Code: NCT07365462·Phase 2·Recruiting·Listed Jan 2026

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A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (EMERGENT TEEN)

for Schizophrenia

Drug: KarXT

Sites in San Francisco, Anaheim +18 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 13 - 17

Code: NCT07288567·Phase 3·Recruiting·Listed Dec 2025

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Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)

for Atrial Fibrillation (AF)

Sites in Los Angeles, La Jolla +20 more locations

Sponsor: Medtronic Cardiac Ablation Solutions

Sex: All·Age: 18+

Code: NCT07298473·Recruiting·Listed Dec 2025

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A Study to Evaluate the Safety and Tolerability of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advanced or Unresectable Hepatocellular Carcinoma (HCC) (ROSETTA HCC-206)

for Hepatocellular Carcinoma (HCC)

Drug: Ipilimumab

Sites in Los Angeles, Duarte +9 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07291076·Phase 1, Phase 2·Recruiting·Listed Dec 2025

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A Study to Learn About the Effects of Cemsidomide in Combination With Elranatamab in Relapsed/Refractory Multiple Myeloma Subjects

for Multiple Myeloma (MM)

Drug: Elranatamab

Sites in Sacramento, Santa Monica +18 more locations

Sponsor: C4 Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07280013·Phase 1·Recruiting·Listed Dec 2025

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ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to Efgartigimod IV in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis With a Partial Clinical Response to Efgartigimod

for AChR-Ab Seropositive Generalized Myasthenia Gravis

Drug: Empasiprubart IV

Sites in Carlsbad +10 more locations

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT07284420·Phase 2·Recruiting·Listed Dec 2025

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Lot-to-lot Consistency Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From 2 Months of Age

for Pneumococcal Immunization

Sites in Los Angeles, Huntington Park +11 more locations

Sponsor: Sanofi

Sex: All·Age: 42 Days - 89 Days·Accepts healthy volunteers

Code: NCT07348692·Phase 3·Recruiting·Listed Jan 2026

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A Study to Investigate Efficacy and Safety With SAR445399 in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

for Hidradenitis Suppurativa

Drug: SAR445399

Sites in North Hollywood +15 more locations

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT07225569·Phase 2·Recruiting·Listed Nov 2025

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A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma

for Multiple Myeloma

Sites in West Hollywood +19 more locations

Sponsor: C4 Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07284758·Phase 2·Recruiting·Listed Dec 2025

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A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy

for Spinal Muscular Atrophy (SMA)

Sites in Stanford +14 more locations

Sponsor: argenx

Sex: All·Age: 5 - 17

Code: NCT07287982·Phase 2·Recruiting·Listed Dec 2025

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A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis

for Secondary Progressive Multiple Sclerosis

Sites in Torrance, Fullerton +18 more locations

Sponsor: Zenas BioPharma (USA), LLC

Sex: All·Age: 18 - 60

Code: NCT07299019·Phase 3·Recruiting·Listed Dec 2025

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Continuation Study of Zasocitinib in Adults With Psoriatic Arthritis

for Psoriatic Arthritis

Drug: Zasocitinib

Sites in Fountain Valley, Thousand Oaks +15 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07286058·Phase 3·Recruiting·Listed Dec 2025

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A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton's Tyrosine Kinase Inhibitor and a B-cell Lymphoma-2 Inhibitor (DAYBreak CLL-201)

for Chronic Lymphocytic Leukemia (CLL)

Sites in Los Angeles, San Diego +23 more locations

Sponsor: Nurix Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07221500·Phase 2·Recruiting·Listed Oct 2025

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