A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
for Macular Degeneration
Sites in Carmel +52 more locations
Sponsor: EyeBiotech Ltd.
Sex: All·Age: 50+
Code: NCT07440225·Phase 2, Phase 3·Recruiting·Listed Feb 2026
Age-related macular degeneration Clinical Trials in Carmel, IN
As of July 2026, 2 paid clinical trials are recruiting for Age-related macular degeneration in Carmel, Indiana. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Related specialties in Carmel
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2 clinical trials for Age-related macular degeneration
·Clear filters·Study to Assess the Adverse Events and How Intravitreal ABBV-6628 Moves Through the Body of Adult Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration
for Geographic Atrophy
Sites in Carmel +4 more locations
Sponsor: AbbVie
Sex: All·Age: 50+
Code: NCT07160179·Phase 1, Phase 2·Recruiting·Listed Sep 2025
Top Research Study Locations in Carmel
Researchers run research studies in Carmel, IN at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| IU Health North Hospital | Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Endometrial Clear Cell Adenocarcinoma | 19 |
| Midwest Eye Institute | Geographic Atrophy Secondary to Age-related Macular Degeneration, Macular Edema Secondary to Inflammation, Geographic Atrophy | 6 |
| Associated Vitreoretinal and Uveitis Consultants | Age-Related Macular Degeneration, Choroidal Neovascularization, Geographic Atrophy | 4 |
| IU Health Joe and Shelly Schwarz Cancer Center | Estrogen-receptor-low Breast Cancer, HPV Positive Cancer, Metastatic Breast Cancer | 3 |
| Indiana Spine Group | Degenerative Disc Disease, Discogenic Low Back Pain, Spinal Deformity | 3 |
| Adverum Clinical | Neovascular Age-Related Macular Degeneration (nAMD), Wet AMD | 3 |
| Ascension St. Vincent Cardiovascular Research Institute | Coronary Artery Disease | 2 |
| Ascension St. Vincent Heart Center | Aortic Insufficiency, Aortic Regurgitation, Aortic Valve Insufficiency | 2 |
| Associated Vitreoretinal and Uveitis Consultants LLC | Macular Edema Secondary to Inflammation | 2 |
| Goodman Campbell Brain and Spine | Brain Tumor, Brain Tumor - Metastatic, Brain Tumor, Adult Meningioma | 2 |
| Midwest Cornea Associates | Neurotrophic Keratitis | 2 |
| Midwest Cornea Associates, LLC | Corneal Scar, Limbal Stem Cell Deficiency | 2 |
| Urology of Indiana | Metastatic Castration-Resistant Prostate Cancer (mCRPC), Non-Muscle Invasive Bladder Neoplasms | 2 |
| Retina Partners Midwest, P.C. | Age - Related Macular Degeneration (AMD), Geographic Atrophy (GA), Age-Related Macular Degeneration | 2 |
| Urology of Indiana - Carmel | High-Risk Non-Muscle-Invasive Bladder Cancer, Metastatic Castration-resistant Prostate Cancer (mCRPC), Prostatic Neoplasms | 2 |
| Ascension St. Vincent Hospital Indianapolis Goodman Campbell Brain and Spine | Intracranial Aneurysm | 1 |
| Ascension St. Vincent's Hospital | Cardiovascular Diseases, Heart Diseases, Heart Valve Diseases | 1 |
| Associated Vitreoretinal & Uveitis Consultants - Carmel | DME, Diabetic Macular Edema, Diabetic Macular Edema (DME) | 1 |
| CBCC Global Research Site:004 | Age-related Wet Macular Degeneration | 1 |
| Claris Investigative Site | Limbal Stem Cell Deficiency | 1 |
| Clinical Trial Site | High Cardiovascular Risk, High Risk Cardiovascular Disease, Hypertension | 1 |
| Glaukos Investigative Site | Persistent Corneal Epithelial Defect | 1 |
| Goodman Campbell Brain and Spine/Ascension | Traumatic Brain Injury | 1 |
| IU Health Beltway Surgery Center | Lumbar Spinal Stenosis | 1 |
| IU Health North / Schwarz Cancer Center | Metastatic Cancer | 1 |
Active & Upcoming Studies in Carmel (2026)
Recruiting trials in Carmel grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (28 active studies)
- Safety and Efficacy of OTL78 (Zopocianine) · Phase 2, Phase 3 · Clinton Bahler
- Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer · Phase 3 · National Cancer Institute (NCI)
Eye & vision (18 active studies)
- A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration · Phase 3 · Amgen
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
Cardiovascular (4 active studies)
- TRIFORMIS RESILIA Real-world Study Assessing Safety and Performance (TRIBLAZE Study) · Edwards Lifesciences
- Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease · Phase 3 · Alnylam Pharmaceuticals
Neurology & pain (3 active studies)
- Rapid Evacuation and Access of Cerebral Hemorrhage Trial · Emory University
- PerQdisc Traditional Feasibility Trial. · Spinal Stabilization Technologies
Common conditions studied in Carmel
- Geographic Atrophy (3 active studies)
- Geographic Atrophy Secondary to Age-related Macular Degeneration (3 active studies)
- Age-Related Macular Degeneration (2 active studies)
- Anatomic Stage I Breast Cancer AJCC v8 (2 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (2 active studies)
- Coronary Artery Disease (2 active studies)
Leading research sponsors in Carmel
- Indiana University
- NRG Oncology
- National Cancer Institute (NCI)
- Alliance for Clinical Trials in Oncology
- Claris Biotherapeutics, Inc.
Frequently asked questions
How many paid clinical trials are currently recruiting in Carmel?
There are approximately 75 recruiting clinical trials in Carmel, Indiana listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Carmel pay participants?
Most recruiting trials in Carmel compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Carmel?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Carmel?
The most common conditions under active study in Carmel include Geographic Atrophy (3), Geographic Atrophy Secondary to Age-related Macular Degeneration (3), Age-Related Macular Degeneration (2), Anatomic Stage I Breast Cancer AJCC v8 (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Carmel?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Carmel on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Carmel?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Carmel?
Recruiting research sites in Carmel include IU Health North Hospital, Midwest Eye Institute, Associated Vitreoretinal and Uveitis Consultants, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Carmel right now?
The largest active categories in Carmel are Cancer & tumors (28), Eye & vision (18), Cardiovascular (4). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
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