Breast oncology Clinical Trials in Chattanooga, TN
As of July 2026, 4 paid clinical trials are recruiting for Breast oncology in Chattanooga, Tennessee. Breast oncology research tests new hormone therapies, HER2-targeted agents, PARP inhibitors, antibody-drug conjugates, and immunotherapy combinations across early-stage and metastatic disease. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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4 clinical trials for Breast oncology
·Clear filters·↓ Download CSVSacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC
Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer
A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)
About research studies in Chattanooga
Chattanooga has approximately 128 recruiting research studies across a wide range of therapeutic areas. Tennessee is home to Vanderbilt University Medical Center and St. Jude Children's Research Hospital — world leaders in pediatric oncology and personalized medicine.
Top Research Study Locations in Chattanooga
Researchers run research studies in Chattanooga, TN at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Southeast Renal Research Institute | Diabetic Kidney Disease (DKD), End Stage Kidney Disease, Focal Segmental Glomerulosclerosis | 5 |
| T C Thompson Children's Hospital | Adrenal Gland Pheochromocytoma, B Acute Lymphoblastic Leukemia, B Lymphoblastic Lymphoma | 5 |
| GSK Investigational Site | Irritable Bowel Syndrome, Multiple Myeloma, Neoplasms, Head and Neck | 4 |
| Tennessee Oncology, PLLC - Chattanooga Downtown | Advanced Non-Small Cell Lung Cancer, Advanced/Metastatic Urothelial Cancer, Cancer of the Prostate | 4 |
| Tennessee Oncology, PLLC - Chattanooga Med Park II | Advanced Renal Cell Carcinoma, Advanced or Metastatic Renal Cell Carcinoma, Advanced/Metastatic Urothelial Cancer | 4 |
| Tennessee Oncology, PLLC - Chattanooga Memorial | Advanced Renal Cell Carcinoma, Advanced or Metastatic Renal Cell Carcinoma, Advanced/Metastatic Urothelial Cancer | 4 |
| Erlanger Health System | AChR-Ab Seropositive Generalized Myasthenia Gravis, Generalized Myasthenia Gravis, Generalized Myasthenia Gravis (gMG) | 4 |
| ClinSearch, LLC | Chronic Obstructive Pulmonary Disease, Liver Fibrosis, Metabolic Dysfunction Associated Steatohepatitis | 3 |
| Erlanger Health, Inc. | Cardiovascular Disease, Endometrioid Ovarian Cancer, Fallopian Tube Cancer | 3 |
| Tennessee Oncology | Advanced Solid Tumors, B-Cell Non-Hodgkins Lymphoma, Colorectal Cancer (CRC) | 3 |
| Tennessee Oncology - Chattanooga | Carcinoma, Non-Small-Cell Lung, Melanoma, Metastatic Castration-resistant Prostate Neoplasms | 3 |
| Tennessee Oncology Chattanooga | Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms, Neoplasm Metastasis | 3 |
| Tennessee Oncology, PLLC - Investigational Drug Services/Supply Storage | Advanced Renal Cell Carcinoma, Advanced or Metastatic Renal Cell Carcinoma, Advanced/Metastatic Urothelial Cancer | 3 |
| Vascular Institute of Chattanooga | Arteriovenous Fistula, Chronic Total Occlusion of Artery of the Extremities, End-stage Renal Disease | 3 |
| Clinical Trial Site | Generalized Myasthenia Gravis, High Cardiovascular Risk, High Risk Cardiovascular Disease | 2 |
| Erlanger Health | Epithelial Ovarian Cancer, Fallopian Tube Cancer, Heart Failure | 2 |
| Tennessee Oncology, PLLC | Acinar Cell Carcinoma, Advanced Cancer, Breast Cancer | 2 |
| Tennessee Oncology, PLLC - Chattanooga East | Advanced/Metastatic Urothelial Cancer, Cancer of the Prostate, Hormone Sensitive Prostate Cancer | 2 |
| University Diabetes & Endocrine Consultants | T1D, T1DM, T1DM - Type 1 Diabetes Mellitus | 2 |
| WR-ClinSearch, LLC | Acute Migraine, Migraine | 2 |
| WR-Clinsearch, LLC | Atherosclerotic Cardiovascular Disease (ASCVD), COVID-19 SARS-CoV-2 Infection, Elevated Lp(a) | 2 |
| Woolfson Eye Institute | Forme Fruste Keratoconus (FFK), Keratoconus, Down Syndrome (DS) | 2 |
| 89bio Clinical Study Site | Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis | 1 |
| Akero Clinical Study Site | MASH With Fibrosis, NASH With Fibrosis | 1 |
| Anthos Investigational | Atrial Fibrillation (AF) | 1 |
Active & Upcoming Studies in Chattanooga (2026)
Recruiting trials in Chattanooga grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (43 active studies)
- Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer · Phase 1, Phase 2 · Pfizer
- Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer · Phase 1, Phase 2 · Pfizer
Diabetes & metabolic (10 active studies)
Neurology & pain (10 active studies)
- A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine · Phase 3 · Kallyope Inc.
- A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine · Phase 3 · Kallyope Inc.
Cardiovascular (8 active studies)
Vaccines (2 active studies)
Pediatric (1 active study)
- CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D) · Phase 1, Phase 2 · COUR Pharmaceutical Development Company, Inc.
Common conditions studied in Chattanooga
- Carcinoma, Non-Small-Cell Lung (5 active studies). Recruiting Carcinoma, Non-Small-Cell Lung studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Generalized Myasthenia Gravis (4 active studies). Recruiting Generalized Myasthenia Gravis studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Breast Cancer (3 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Chronic Lymphocytic Leukemia (3 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Chronic Obstructive Pulmonary Disease (3 active studies). COPD research evaluates biologic therapies, triple-inhaler combinations, and new anti-inflammatory agents to reduce exacerbations.
- Fallopian Tube Cancer (3 active studies). Recruiting Fallopian Tube Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Chattanooga
- AstraZeneca
- Pfizer
- Children's Oncology Group
- Boehringer Ingelheim
- Eli Lilly and Company
Local regulations and guidelines
Clinical trials in Tennessee are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Tennessee research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Chattanooga. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Chattanooga
Hipa.ai aggregates every recruiting study in Chattanooga from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Chattanooga?
There are approximately 128 recruiting clinical trials in Chattanooga, Tennessee listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Chattanooga pay participants?
Most recruiting trials in Chattanooga compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Chattanooga?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Chattanooga?
The most common conditions under active study in Chattanooga include Carcinoma, Non-Small-Cell Lung (5), Generalized Myasthenia Gravis (4), Breast Cancer (3), Chronic Lymphocytic Leukemia (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Chattanooga?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Chattanooga on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Chattanooga?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Chattanooga?
Recruiting research sites in Chattanooga include Southeast Renal Research Institute, T C Thompson Children's Hospital, GSK Investigational Site, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Chattanooga right now?
The largest active categories in Chattanooga are Cancer & tumors (43), Diabetes & metabolic (10), Neurology & pain (10). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.