Oncology Clinical Trials in Denver, CO
As of September 2026, 166 paid clinical trials are recruiting for Oncology in Denver, Colorado. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Denver
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
A Study of SHY-ONC6, a Novel Proteasome Inhibitor, in Adults With Advanced or Metastatic Solid Tumors
A Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation
169 clinical trials for Oncology
·Clear filters·Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer
A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma
Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy
A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer
Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)
Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects
A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)
MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer
A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.
A Study of ASP3082 in Adults With Advanced Solid Tumors
Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma
Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)
Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC
A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer
A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis
A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer
Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1
Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma
A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)
TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers
Top Research Study Locations in Denver
Researchers run research studies in Denver, CO at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Colorado Blood Cancer Institute | Multiple Myeloma, Non-Hodgkin Lymphoma, Acute Myeloid Leukemia | 44 |
| National Jewish Health | Cystic Fibrosis, Pulmonary Hypertension, Asthma | 41 |
| Sarah Cannon Research Institute at HealthONE | Advanced Solid Tumor, Solid Tumor, Metastatic Solid Tumor | 26 |
| Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center | Acute Myeloid Leukemia, Malignant Solid Neoplasm, Mixed Phenotype Acute Leukemia | 17 |
| Rocky Mountain Cancer Centers | Breast Cancer, Colorectal Neoplasms, Breast Neoplasms | 16 |
| Kaiser Permanente-Franklin | Lung Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 14 |
| UCHealth - Cherry Creek | Anatomic Stage II Breast Cancer AJCC v8, Muscle Invasive Bladder Urothelial Carcinoma, Stage II Bladder Cancer AJCC v8 | 14 |
| University of Colorado | B Cell Lymphoma, B-Cell Non-Hodgkin's Lymphoma, CADASIL | 13 |
| Denver Health Medical Center | Acute Respiratory Failure, Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm >= 5.0 Centimeters in Female (Disorder) | 12 |
| Children's Hospital Colorado | ALL, AML, Acute Respiratory Distress Syndrome | 10 |
| University of Colorado Denver | Amyotrophic Lateral Sclerosis, Attention, Behavioral Variant Frontotemporal Dementia (bvFTD) | 10 |
| Rocky Mountain Cancer Centers, LLP | Colorectal Neoplasms, Urothelial Cancer, Advanced Renal Cell Carcinoma | 9 |
| Denver Health and Hospital Authority | Sepsis, ARDS, Acute Otitis Media | 9 |
| Saint Joseph Hospital - Cancer Centers of Colorado | Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma | 8 |
| Presbyterian - Saint Lukes Medical Center - Health One | Malignant Solid Neoplasm, Acral Lentiginous Melanoma, Anatomic Stage I Breast Cancer AJCC v8 | 7 |
| Rocky Mountain Cancer Centers-Midtown | Malignant Solid Neoplasm, Non-Hodgkin Lymphoma, Acral Lentiginous Melanoma | 7 |
| Rocky Mountain Cancer Centers-Rose | Malignant Solid Neoplasm, Non-Hodgkin Lymphoma, Acral Lentiginous Melanoma | 7 |
| AdventHealth Porter | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8 | 6 |
| National Jewish Health-Main Campus | Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma | 6 |
| Sarah Cannon Research Institute | Gastric Cancer, Locally Advanced or Metastatic Solid Tumors, Pancreatic Cancer | 6 |
| The Women's Imaging Center | Malignant Solid Neoplasm, Acral Lentiginous Melanoma, Anatomic Stage I Breast Cancer AJCC v8 | 6 |
| Cancer Center of Colorado at Sloan's Lake | Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma | 5 |
| Children's Hospital of Colorado | Adolescent, Bowel Incontinence, CBL Syndrome | 5 |
| Denver Arthritis Clinic - Lowry | Gout, Psoriatic Arthritis, Systemic Lupus Erythematosus | 5 |
| Denver Health | Angina, Stable, Cardiovascular Diseases, Communication Disabilities | 5 |
Active & Upcoming Studies in Denver (2026)
Recruiting trials in Denver grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (222 active studies)
- Trial to Evaluate an Educational Video Series for Women in Breast Cancer Treatment · University of Colorado, Denver
- A Study of Elranatamab Outpatient Administration in Patients With Relapsed/Refractory Multiple Myeloma · Phase 2 · SCRI Development Innovations, LLC
Cardiovascular (16 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- Optimal Ventilation for Cardiac Arrest · Children's Hospital of Philadelphia
Diabetes & metabolic (10 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes · Insulet Corporation
Mental health & behavior (7 active studies)
- Occupational Therapy for Mental Health and Engagement in Neurorehabilitation · Colorado State University
- Measuring Communal Coping in Dual-smoking Couples Making a Quit Attempt · University of Colorado, Denver
Pediatric (7 active studies)
- Meet Me on the Pitch: Developing and Testing a Community-Based Sports and Behavioral Health Intervention for Youth · University of California, San Francisco
- Interventions to De-implement Unnecessary Antibiotic Prescribing for Children With Ear Infections · Intermountain Health Care, Inc.
Neurology & pain (6 active studies)
- CF Wellness Program · Johns Hopkins University
- A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101 · Kyverna Therapeutics
Eye & vision (5 active studies)
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003) · Phase 2, Phase 3 · EyeBiotech Ltd.
- Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS) · Phase 3 · Adverum Biotechnologies, Inc.
HIV / STI (3 active studies)
- Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention · Gilead Sciences
- A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062) · Phase 2, Phase 3 · Merck Sharp & Dohme LLC
Vaccines (2 active studies)
- Phase 2a Multiple Ascending Dose Study in Hospitalized Patients With Pneumonia. · Phase 2 · Vasomune Therapeutics, Inc.
- SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry · Massive Bio, Inc.
Common conditions studied in Denver
- Multiple Myeloma (18 active studies)
- Breast Cancer (16 active studies)
- Advanced Solid Tumor (15 active studies)
- Endometrial Cancer (11 active studies)
- Ovarian Cancer (11 active studies)
- Solid Tumor (11 active studies)
Leading research sponsors in Denver
- University of Colorado, Denver
- AstraZeneca
- Children's Oncology Group
- National Cancer Institute (NCI)
- Eli Lilly and Company
Frequently asked questions
How many paid clinical trials are currently recruiting in Denver?
There are approximately 521 recruiting clinical trials in Denver, Colorado listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Denver pay participants?
Most recruiting trials in Denver compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Denver?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Denver?
The most common conditions under active study in Denver include Multiple Myeloma (18), Breast Cancer (16), Advanced Solid Tumor (15), Endometrial Cancer (11), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Denver?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Denver on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Denver?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Denver?
Recruiting research sites in Denver include Colorado Blood Cancer Institute, National Jewish Health, Sarah Cannon Research Institute at HealthONE, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Denver right now?
The largest active categories in Denver are Cancer & tumors (222), Cardiovascular (16), Diabetes & metabolic (10). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.