Paid Clinical Trials in Highlands Ranch, CO
As of August 2026, 36 paid clinical trials are recruiting in Highlands Ranch, Colorado. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Highlands Ranch offers studies at sites including UCHealth Highlands Ranch Hospital for conditions such as Breast Cancer, Anatomic Stage II Breast Cancer AJCC v8, Muscle Invasive Bladder Urothelial Carcinoma, Ovarian Carcinoma. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Highlands Ranch
Trials by drug in Highlands Ranch
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34 clinical trials
Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)
A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver)
A Study to Test DSP107 in Combination With Atezolizumab in Comparison With Fruquintinib as a New Treatment for Colorectal Cancer.
Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer
Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer
Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial
Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response
Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer
The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial
Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study
Letrozole in Uterine Leiomyosarcoma
Neoadjuvant Pembrolizumab and Axitinib in Renal Cell Carcinoma With Inferior Vena Cava Tumor Thrombus
Improving Care for Rural Patients With Solid Tumors
The Immune System's Response to Young Women's Breast Cancer
A Lifetime Partnership With Patients Who Have or May be at Risk of Having Cancer
A Novel Patient Decision Aid for Surgical Treatment Options in Early-Stage Breast Cancer
Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma
Top Research Study Locations in Highlands Ranch
Researchers run research studies in Highlands Ranch, CO at 9 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| UCHealth Highlands Ranch Hospital | Anatomic Stage II Breast Cancer AJCC v8, Breast Cancer, Muscle Invasive Bladder Urothelial Carcinoma | 28 |
| Highlands Ranch Hospital | Bladder Cancer, Breast Cancer, Cervical Cancer | 2 |
| Highlands Ranch Medical Center | Cancer Risk | 1 |
| Hilands Ranch Hospital | Inferior Vena Cava Thrombosis, Kidney Cancer, Renal Cancer | 1 |
| UCHealth Cancer Center Pharmacy - Highlands Ranch Hospital | Advanced Liver Cancers | 1 |
| UCHealth Family Medicine - Littleton | Obesity | 1 |
| UCHealth Primary Care - Highlands Ranch | Obesity | 1 |
| University of Colorado Cancer Center - Highlands Ranch Hospital | Colorectal Cancer | 1 |
| University of Colorado Health - Highlands Ranch Hospital | Prostate Cancer Metastatic | 1 |
Active & Upcoming Studies in Highlands Ranch (2026)
Recruiting trials in Highlands Ranch grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (33 active studies)
- Trial to Evaluate an Educational Video Series for Women in Breast Cancer Treatment · University of Colorado, Denver
- Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer · Phase 3 · National Cancer Institute (NCI)
Diabetes & metabolic (1 active study)
- PATHWEIGH: Pragmatic Weight Management in Primary Care · University of Colorado, Denver
Common conditions studied in Highlands Ranch
- Breast Cancer (4 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (3 active studies)
- Muscle Invasive Bladder Urothelial Carcinoma (3 active studies)
- Ovarian Carcinoma (2 active studies)
- Stage II Bladder Cancer AJCC v8 (2 active studies)
- Stage IIIA Bladder Cancer AJCC v8 (2 active studies)
Leading research sponsors in Highlands Ranch
- NRG Oncology
- National Cancer Institute (NCI)
- University of Colorado, Denver
- Alliance for Clinical Trials in Oncology
- Merck Sharp & Dohme LLC
Frequently asked questions
How many paid clinical trials are currently recruiting in Highlands Ranch?
There are approximately 36 recruiting clinical trials in Highlands Ranch, Colorado listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Highlands Ranch pay participants?
Most recruiting trials in Highlands Ranch compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Highlands Ranch?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Highlands Ranch?
The most common conditions under active study in Highlands Ranch include Breast Cancer (4), Anatomic Stage II Breast Cancer AJCC v8 (3), Muscle Invasive Bladder Urothelial Carcinoma (3), Ovarian Carcinoma (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Highlands Ranch?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Highlands Ranch on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Highlands Ranch?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Highlands Ranch?
Recruiting research sites in Highlands Ranch include UCHealth Highlands Ranch Hospital, Highlands Ranch Hospital, Highlands Ranch Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Highlands Ranch right now?
The largest active categories in Highlands Ranch are Cancer & tumors (33), Diabetes & metabolic (1). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.