Paid Clinical Trials in Denver, CO
As of September 2026, 524 paid clinical trials are recruiting in Denver, Colorado. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Denver offers studies at sites including Colorado Blood Cancer Institute for conditions such as Multiple Myeloma, Advanced Solid Tumor, Breast Cancer, Endometrial Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Denver
Trials by drug in Denver
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Newly added in Denver
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Threat Interpretation Bias as Cognitive Marker and Treatment Target in Pediatric Anxiety: R33 Phase
Non-invasive Prediction of EArly Cardiac rEjection
Study of AZD0120 in Newly Diagnosed Multiple Myeloma Ineligible for ASCT
A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.
A Study to Investigate the Efficacy and Safety of Apraglutide Compared With Placebo in Adult Participants With Short Bowel Syndrome Associated With Intestinal Failure (SBS-IF)
473 clinical trials
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer
A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris
Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer
Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention
Phase 3 Study of Telitacicept in Active Primary Sjögren's Disease
Phase 2 Study to Assess the Safety and Efficacy of ANG003
A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE)
A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With Uncontrolled Gout
Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)
PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease
A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults
Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
Study of DONQ52 in Active Celiac Disease
Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers
A Study to Find Out if BI 764198 Helps Adults and Adolescents With a Kidney Condition Called Focal Segmental Glomerulosclerosis (FSGS)
A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma
A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
A Study of Dotinurad Versus Allopurinol in Participants With Gout
A Study of Dotinurad Versus Allopurinol in Tophaceous Gout
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer
Phase IIIb Study of Ribociclib + ET in Early Breast Cancer
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer
Top Research Study Locations in Denver
Researchers run research studies in Denver, CO at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Colorado Blood Cancer Institute | Multiple Myeloma, Non-Hodgkin Lymphoma, Acute Myeloid Leukemia | 44 |
| National Jewish Health | Cystic Fibrosis, Pulmonary Hypertension, Asthma | 41 |
| Sarah Cannon Research Institute at HealthONE | Advanced Solid Tumor, Solid Tumor, Metastatic Solid Tumor | 26 |
| Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center | Acute Myeloid Leukemia, Malignant Solid Neoplasm, Mixed Phenotype Acute Leukemia | 17 |
| Kaiser Permanente-Franklin | Lung Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 14 |
| Rocky Mountain Cancer Centers | Breast Cancer, Colorectal Neoplasms, Breast Neoplasms | 14 |
| UCHealth - Cherry Creek | Anatomic Stage II Breast Cancer AJCC v8, Muscle Invasive Bladder Urothelial Carcinoma, Stage II Bladder Cancer AJCC v8 | 14 |
| University of Colorado | B Cell Lymphoma, B-Cell Non-Hodgkin's Lymphoma, CADASIL | 13 |
| Children's Hospital Colorado | ALL, AML, Acute Respiratory Distress Syndrome | 12 |
| Denver Health Medical Center | Acute Respiratory Failure, Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm >= 5.0 Centimeters in Female (Disorder) | 11 |
| University of Colorado Denver | Amyotrophic Lateral Sclerosis, Attention, Behavioral Variant Frontotemporal Dementia (bvFTD) | 10 |
| Denver Health and Hospital Authority | Sepsis, ARDS, Acute Otitis Media | 9 |
| Saint Joseph Hospital - Cancer Centers of Colorado | Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma | 8 |
| AdventHealth Porter | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8 | 7 |
| Sarah Cannon Research Institute | Gastric Cancer, Locally Advanced or Metastatic Solid Tumors, Pancreatic Cancer | 7 |
| National Jewish Health-Main Campus | Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma | 6 |
| Rocky Mountain Cancer Centers, LLP | Colorectal Neoplasms, Urothelial Cancer, Advanced/Metastatic Urothelial Cancer | 5 |
| Cancer Center of Colorado at Sloan's Lake | Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma | 5 |
| Children's Hospital of Colorado | Adolescent, Bowel Incontinence, CBL Syndrome | 5 |
| Denver Arthritis Clinic - Lowry | Gout, Psoriatic Arthritis, Systemic Lupus Erythematosus | 5 |
| Mountain View Clinical Research | Major Depressive Disorder, Depressive Disorder, Major, Depressive Disorder, Treatment-Resistant | 5 |
| Presbyterian - Saint Lukes Medical Center - Health One | Acral Lentiginous Melanoma, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 5 |
| Rocky Mountain Cancer Centers-Midtown | Acral Lentiginous Melanoma, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 5 |
| Rocky Mountain Cancer Centers-Rose | Acral Lentiginous Melanoma, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 5 |
| University of Colorado, Denver | ACUTE SINUSITIS, ARDS, Acute Otitis Media (AOM) | 5 |
Active & Upcoming Studies in Denver (2026)
Recruiting trials in Denver grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (217 active studies)
- Trial to Evaluate an Educational Video Series for Women in Breast Cancer Treatment · University of Colorado, Denver
- A Study of Elranatamab Outpatient Administration in Patients With Relapsed/Refractory Multiple Myeloma · Phase 2 · SCRI Development Innovations, LLC
Cardiovascular (17 active studies)
- Testing Heart Failure Resilience Intervention for Caregivers (HEROIC) in Advanced Heart Failure · Phase 2 · Johns Hopkins University
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
Mental health & behavior (10 active studies)
- Feasibility of a Modified Dental Comfort Position for Pediatric Patients Receiving Dental Exams · Children's Hospital Colorado
- Device for Treating Generalized Anxiety · BTL Industries Ltd.
Diabetes & metabolic (10 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes · Insulet Corporation
Pediatric (9 active studies)
- Feasibility of a Modified Dental Comfort Position for Pediatric Patients Receiving Dental Exams · Children's Hospital Colorado
- Meet Me on the Pitch: Developing and Testing a Community-Based Sports and Behavioral Health Intervention for Youth · University of California, San Francisco
Neurology & pain (7 active studies)
- A Study to Assess the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine · Phase 3 · Kallyope Inc.
- CF Wellness Program · Johns Hopkins University
Eye & vision (7 active studies)
- A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-004) · Phase 3 · Merck Sharp & Dohme LLC
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003) · Phase 2, Phase 3 · EyeBiotech Ltd.
HIV / STI (4 active studies)
Vaccines (2 active studies)
- Phase 2a Multiple Ascending Dose Study in Hospitalized Patients With Pneumonia. · Phase 2 · Vasomune Therapeutics, Inc.
- SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry · Massive Bio, Inc.
Common conditions studied in Denver
- Multiple Myeloma (18 active studies)
- Advanced Solid Tumor (14 active studies)
- Breast Cancer (14 active studies)
- Endometrial Cancer (11 active studies)
- Ovarian Cancer (11 active studies)
- Solid Tumor (10 active studies)
Leading research sponsors in Denver
- University of Colorado, Denver
- AstraZeneca
- Children's Oncology Group
- National Cancer Institute (NCI)
- Eli Lilly and Company
Frequently asked questions
How many paid clinical trials are currently recruiting in Denver?
There are approximately 524 recruiting clinical trials in Denver, Colorado listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Denver pay participants?
Most recruiting trials in Denver compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Denver?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Denver?
The most common conditions under active study in Denver include Multiple Myeloma (18), Advanced Solid Tumor (14), Breast Cancer (14), Endometrial Cancer (11), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Denver?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Denver on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Denver?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Denver?
Recruiting research sites in Denver include Colorado Blood Cancer Institute, National Jewish Health, Sarah Cannon Research Institute at HealthONE, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Denver right now?
The largest active categories in Denver are Cancer & tumors (217), Cardiovascular (17), Mental health & behavior (10). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.