Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies
for Cancer
8 locations incl. Fort Smith
Sponsor: Elephas
Sex: All·Age: 18+
Code: NCT07327489·Recruiting
ENT Clinical Trials in Frederick, MD
As of June 2026, 1 paid clinical trial is recruiting for ENT in Frederick, Maryland. ENT (otolaryngology) trials evaluate new treatments for hearing loss, swallowing disorders, and head and neck cancers — covering pharmacologic, surgical, and rehabilitative approaches. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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1 clinical trial for ENT
·Clear filters·↓ Download CSVAbout research studies in Frederick
Frederick has approximately 31 recruiting research studies across a wide range of therapeutic areas. Maryland hosts Johns Hopkins Medicine and the NIH Clinical Center in Bethesda, giving participants access to some of the most advanced early-phase research in the country.
Top Research Study Locations in Frederick
Researchers run research studies in Frederick, MD at 18 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| FMH James M Stockman Cancer Institute | Breast Cancer, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 8 |
| James M Stockman Cancer Institute | Breast Cancer, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung | 5 |
| Frederick Memorial Hospital | Breast Cancer, Cognitive Impairments, Plasma Cell Myeloma | 4 |
| Frederick Health Hospital | Advanced Solid Tumors Cancer, Bladder Cancer, Cancer | 2 |
| Frederick Health Hospital- James M Stockman Cancer Institute | Extensive-stage Small-cell Lung Cancer, Non-small Cell Lung Cancer | 2 |
| Frederick Health Regional System | Cancer, Non-Small Cell Lung Cancer | 2 |
| Frederick Oncology Hematology Associates | Breast Cancer, Malignant Neoplasm | 2 |
| Ability x Ottobock.care | Lower Extremity, Pareses | 1 |
| Cumberland Valley Retina Consultants | Macular Telangiectasia Type 2 (MacTel) | 1 |
| Frederick County Health Department, Street Safe Program | Addiction, Drug Use, HIV Infections | 1 |
| Frederick Health-James M Stockman Cancer Institute | Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion | 1 |
| Frederick Memorial Hospital Crestwood | Breast Cancer, Cognitive Impairments | 1 |
| James M. Stockman Cancer Institute | Homeostatic Iron Regulator Gene-related Hereditary Hemochromatosis | 1 |
| Johns Hopkins Community Physicians Frederick | Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance) | 1 |
| Monocacy Surgery Center, LLC | Lumbar Spinal Stenosis | 1 |
| NCI Frederick Cancer Research Center | Healthy Donors | 1 |
| National Pain and Spine Centers | Lumbar Spinal Stenosis | 1 |
| Thomas Johnson Surgery Center | Lumbar Spinal Stenosis | 1 |
Active & Upcoming Studies in Frederick (2026)
Recruiting trials in Frederick grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (22 active studies)
- Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy · Phase 3 · Alliance for Clinical Trials in Oncology
- Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies · Elephas
HIV / STI (1 active study)
- Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation · Johns Hopkins University
Mental health & behavior (1 active study)
- Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation · Johns Hopkins University
Eye & vision (1 active study)
- Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants · Phase 4 · Neurotech Pharmaceuticals
Common conditions studied in Frederick
- Breast Cancer (4 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Cancer (2 active studies). Recruiting Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Addiction (1 active study). Recruiting Addiction studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Advanced Solid Tumors Cancer (1 active study). Recruiting Advanced Solid Tumors Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Anatomic Stage I Breast Cancer AJCC v8 (1 active study). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Anatomic Stage II Breast Cancer AJCC v8 (1 active study). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
Leading research sponsors in Frederick
- NRG Oncology
- National Cancer Institute (NCI)
- Alliance for Clinical Trials in Oncology
- AstraZeneca
- BioNTech SE
Local regulations and guidelines
Clinical trials in Maryland are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Maryland research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Frederick. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Frederick
Hipa.ai aggregates every recruiting study in Frederick from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Frederick?
There are approximately 31 recruiting clinical trials in Frederick, Maryland listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Frederick pay participants?
Most recruiting trials in Frederick compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Frederick?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Frederick?
The most common conditions under active study in Frederick include Breast Cancer (4), Cancer (2), Addiction (1), Advanced Solid Tumors Cancer (1), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Frederick?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Frederick on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Frederick?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Frederick?
Recruiting research sites in Frederick include FMH James M Stockman Cancer Institute, James M Stockman Cancer Institute, Frederick Memorial Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Frederick right now?
The largest active categories in Frederick are Cancer & tumors (22), HIV / STI (1), Mental health & behavior (1). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
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