Paid Clinical Trials in Illinois

Illinois has 2,971 paid clinical trials enrolling now across cities including Chicago, Peoria and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Illinois include Northwestern Medicine, University of Chicago Medicine and Rush, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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2,971 clinical trials

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A Study to Assess Adverse Events, Change in Disease Activity and How Intravenous (IV) ABBV901 Moves Through the Body Alone or in Combination With Bevacizumab in Adult Participants With Ovarian Cancer

for Ovarian Cancer

Drug: Bevacizumab

5 locations incl. Denver

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07278336·Phase 1·Recruiting

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A Study to Assess the Efficacy and Safety of Debio 4126 in Participants With Acromegaly Previously Treated With Somatostatin Analogs

for Acromegaly

9 locations incl. Los Angeles

Sponsor: Debiopharm International SA

Sex: All·Age: 18+

Code: NCT06930625·Phase 3·Recruiting

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A Study to Evaluate the Efficacy and Safety of Cannabidiol Oral Solution (CBD-OS [GWP42003-P, JZP926]) for the Treatment of Focal-Onset Seizures

for Focal Seizures

24 locations incl. Phoenix

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 12 - 75

Code: NCT07233239·Phase 1·Recruiting

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Observational Study of VYKAT™ XR in Patients With Prader-Willi Syndrome

for Prader-Willi Syndrome

15 locations incl. Los Angeles

Sponsor: Soleno Therapeutics, Inc.

Sex: All·Age: 4+

Code: NCT07450664·Enrolling By Invitation

Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial

for Muscle Invasive Bladder Urothelial Carcinoma

143 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07061964·Phase 2·Recruiting

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Detrusor Nerve Radiofrequency Ablation for Overactive Bladder in Women

for Overactive Bladder

9 locations incl. Palo Alto

Sponsor: InMode MD Ltd.

Sex: Female·Age: 22 - 80

Code: NCT07209397·Recruiting

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Long-term Efficacy and Safety Extension (LTE) Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria

for Chronic Spontaneous Urticaria

19 locations incl. Birmingham

Sponsor: Celldex Therapeutics

Sex: All·Age: 18+

Code: NCT07256392·Phase 3·Enrolling By Invitation

Mirena for the Treatment of Nonatypical Endometrial Hyperplasia for 6 Months

for Endometrial Hyperplasia

69 locations incl. Birmingham

Sponsor: Bayer

Sex: Female·Age: 18+

Code: NCT06904274·Phase 3·Recruiting

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A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

for Parkinson's Disease

Drug: Prasinezumab

42 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 50 - 85

Code: NCT07174310·Phase 3·Recruiting

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REGN7508 Versus Acetylsalicylic Acid (ASA) for Venous Thromboprophylaxis After Total Knee Arthroplasty in Adult Participants

for Symptomatic Venous Thromboembolism (VTE)

23 locations incl. Rancho Mirage

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07213778·Phase 3·Recruiting

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A Study of KT-621 Administered Orally to Participants With Moderate to Severe Atopic Dermatitis

for Atopic Dermatitis

20 locations incl. Birmingham

Sponsor: Kymera Therapeutics, Inc.

Sex: All·Age: 12 - 75

Code: NCT07217015·Phase 2·Recruiting

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A Study to Evaluate How the Study Drug Moves Through the Body, Adverse Events, and How the Body Tolerates ABBV-547 Injections

for Healthy Volunteer

21 locations incl. Birmingham

Sponsor: AbbVie

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07232004·Phase 1·Recruiting

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Home Based Functional Balance Intervention for Multiple Sclerosis

for Multiple Sclerosis

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 40 - 90

Code: NCT07355387·Recruiting

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Study of MRM-3379 in Male Participants With Fragile X Syndrome (BLOOM)

for Fragile X Syndrome

15 locations incl. Phoenix

Sponsor: Mirum Pharmaceuticals, Inc.

Sex: Male·Age: 13 - 45

Code: NCT07209462·Phase 2·Recruiting

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A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

for Epithelial Ovarian Cancer

66 locations incl. Birmingham

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT06890338·Phase 2·Recruiting

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Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants

for Macular Telangiectasia Type 2 (MacTel)

23 locations incl. La Jolla

Sponsor: Neurotech Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06971939·Phase 4·Recruiting

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Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy

for Diabetic Peripheral Neuropathic Pain

75 locations incl. Birmingham

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 80

Code: NCT07231419·Phase 3·Recruiting

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SGLT2i in Kidney Stones

for Kidney Stones

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 70

Code: NCT07055282·EARLY_Phase 1·Recruiting

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A Study to Assess the Adverse Events, Change in Disease Activity, and How Oral ABBV-711 Tablets Move Through the Body as a Monotherapy and in Combination With Intravenously Infused Budigalimab (ABBV-181), in Adults With Advanced Squamous Tumors

for Advanced Squamous Tumors

6 locations incl. Duarte

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07241039·Phase 1·Recruiting

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PSMA PET for Surveillance After Focal Therapy

for Prostate Cancer (Adenocarcinoma)

1 location in Chicago

Sponsor: University of Chicago

Sex: Male·Age: 18+

Code: NCT07115914·Recruiting

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Study of Reformulated Levulan Kerastick Plus PDT for Actinic Keratosis on Face and Scalp

for Actinic Keratosis

10 locations incl. Fremont

Sponsor: Sun Pharmaceutical Industries, Inc.

Sex: All·Age: 18 - 85

Code: NCT07144345·Phase 3·Recruiting

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Phase 2a Study of VX-407 in Participants With ADPKD Who Have a Subset of PKD1 Gene Variants (AGLOW)

for Autosomal Dominant Polycystic Kidney Disease (ADPKD)

26 locations incl. Alabaster

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 65

Code: NCT07161037·Phase 2·Recruiting

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A Study of ABBV-295 Subcutaneous Injections to Assess Adverse Events and Pharmacokinetics in Adult Participants With Obesity

for Obesity

2 locations incl. Anaheim

Sponsor: AbbVie

Sex: All·Age: 18 - 65

Code: NCT07291232·Phase 1·Recruiting

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Self-sampling to Optimize Anal Lesion Outcomes

for Anal Cancer

3 locations incl. Chicago

Sponsor: Medical College of Wisconsin

Sex: All·Age: 35+·Accepts healthy volunteers

Code: NCT07192055·Recruiting

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Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

for Metastatic Colorectal Cancer (CRC)

Drug: Bevacizumab

58 locations incl. Goodyear

Sponsor: Summit Therapeutics

Sex: All·Age: 18+

Code: NCT07228832·Phase 3·Recruiting

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This Study is a Non-interventional Disease Registry of Adolescent and Adult Patients With Atopic Dermatitis Who Initiate or Switch Any Systemic Treatment

for Atopic Dermatitis

43 locations incl. Birmingham

Sponsor: Sanofi

Sex: All·Age: 12+

Code: NCT07290803·Recruiting

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Social Cognition Training in Individuals With Huntington's Disease

for Huntington&#39

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18 - 65

Code: NCT06828471·Recruiting

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People With Multiple Sclerosis Treated With Ocrelizumab and GLP-1 Agonists

for Multiple Sclerosis

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18 - 70

Code: NCT07207148·Recruiting

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Improving Walking After Spinal Cord Injury

for Spinal Cord Injury

1 location in Chicago

Sponsor: Shirley Ryan AbilityLab

Sex: All·Age: 18 - 75

Code: NCT07223710·Phase 1, Phase 2·Not Yet Recruiting

A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

for Systemic Lupus Erythematosus (With and Without Nephritis)

13 locations incl. Phoenix

Sponsor: Allogene Therapeutics

Sex: All·Age: 18 - 69

Code: NCT07085104·Phase 1·Recruiting

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A 16-Week Study to Learn About the Study Medicine Called Ritlecitinib in Adults With Long Lasting Painful Red Skin Lumps, Known by the Medical Term, Hidradenitis Suppurativa, or HS.

for Hidradenitis Suppurativa

Drug: Ritlecitinib

32 locations incl. Phoenix

Sponsor: Pfizer

Sex: All·Age: 18 - 75

Code: NCT07228390·Phase 2·Recruiting

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Probiotics in Adults With Rheumatoid Arthritis

for Rheumatoid Arthritis (RA)

1 location in Chicago

Sponsor: Ancilia Biosciences

Sex: All·Age: 18+

Code: NCT07304505·Recruiting

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Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia

for B-cell Acute Lymphoblastic Leukemia (B-ALL)

6 locations incl. Duarte

Sponsor: AstraZeneca

Sex: All·Age: 12+

Code: NCT07109219·Phase 1, Phase 2·Recruiting

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A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

for Alzheimers Disease

Drug: Trontinemab

33 locations incl. Phoenix

Sponsor: Hoffmann-La Roche

Sex: All·Age: 50 - 90

Code: NCT07170150·Phase 3·Recruiting

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A Study of NNZ-2591 in Pediatric Participants With Phelan-McDermid Syndrome

for Phelan-McDermid Syndrome

9 locations incl. Glendale

Sponsor: Neuren Pharmaceuticals Limited

Sex: All·Age: 3 - 12

Code: NCT07281079·Phase 3·Recruiting

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STOP-UC: De-escalation of Therapy in Patients With Ulcerative Colitis With Histological Remission

for Ulcerative Colitis (UC)

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 75

Code: NCT06693310·Recruiting

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A Clinical Study of Enlicitide in Participants With High Cholesterol (MK-0616-037)

for Hyperlipidemia

35 locations incl. Birmingham

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18 - 64

Code: NCT07216482·Phase 3·Recruiting

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A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis

for Secondary Progressive Multiple Sclerosis (SPMS)

Drug: Remibrutinib

30 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT07225504·Phase 3·Recruiting

Apply to this trial

Type 1 Diabetes and Obstructive Sleep Apnea

for Sleep Apnea, Obstructive

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 50

Code: NCT06915831·Recruiting

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LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

for Ulcerative Colitis

Drug: LY4268989

41 locations incl. Scottsdale

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 80

Code: NCT07186101·Phase 2·Recruiting

Apply to this trial