Cardiology Clinical Trials in Indianapolis, IN
As of August 2026, 41 paid clinical trials are recruiting for Cardiology in Indianapolis, Indiana. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Indianapolis
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
42 clinical trials for Cardiology
·Clear filters·A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
Assessment of CCM in HF With Higher Ejection Fraction
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
Tracking Results of Ablations to Combat AF Registry Generation 2
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
An Open-Label ProSpective MultiCENTer Study to Evaluate Safety and Tolerability of Dry Powder Inhaled Treprostinil in PH
Artificial Intelligence Mapping and Ablation of Non-Pulmonary Vein Electrical Drivers of AF Study
Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System
PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm
Virtue® SAB in the Treatment of Coronary ISR Trial
The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation
The Fourth Left Atrial Appendage Occlusion Study
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
Leg Heat Therapy in Peripheral Artery Disease
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery
Delivering Food Resources & Kitchen Skills (FoRKS) to Adults With Food Insecurity and Hypertension
MIND Foods and Aerobic Training in Black Adults With HTN
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women
ATrial Tachycardia PAcing Therapy in Congenital Heart
Left vs Left Randomized Clinical Trial
Ondansetron for the Management of Atrial Fibrillation
Pulmonary Hypertension Association Registry
Leg Heat Therapy in Heart Failure With Preserved Ejection Fraction
A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
Prospective Global Registry for the Study of Chronic Total Occlusion Intervention
Alleviant ALLAY-HF Study
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
Late Subclinical Cardiovascular Disease in Testicular Cancer Survivors
Top Research Study Locations in Indianapolis
Researchers run research studies in Indianapolis, IN at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Indiana University | Alzheimer Disease, Amyotrophic Lateral Sclerosis, Dementia | 103 |
| Riley Hospital for Children | Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 63 |
| Indiana University School of Medicine | Dementia, Alzheimers Disease, Alzheimers Disease, Familial | 51 |
| Indiana University/Melvin and Bren Simon Cancer Center | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Stage IV Lung Cancer AJCC v8 | 33 |
| Indiana University Melvin and Bren Simon Comprehensive Cancer Center | Small Cell Lung Cancer, Germ Cell Tumor, Prostate Cancer | 28 |
| Indiana University Health | Myasthenia Gravis, Acetabulum Fractures, Acute Ischemic Stroke | 21 |
| Community Health Network | Colorectal Cancer, Pancreatic Ductal Adenocarcinoma, Head and Neck Squamous Cell Carcinoma | 20 |
| Indiana University Health University Hospital | Eosinophilic Esophagitis, Gastroparesis, Obesity or Overweight | 20 |
| Saint Catherine Hospital | Anatomic Stage II Breast Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Advanced Esophageal Adenocarcinoma | 20 |
| Indiana University Hospital | Gastroparesis, Abnormal Uterine Bleeding, Achalasia | 17 |
| IU Health Methodist Hospital | Coronary Artery Disease, Atrial Fibrillation, Breast Implant; Complications | 15 |
| Ascension Saint Vincent Indianapolis Hospital | Acute Myeloid Leukemia, Malignant Solid Neoplasm, Mixed Phenotype Acute Leukemia | 14 |
| Dawes Fretzin Clinical Research Group, LLC | Atopic Dermatitis, Eczema, Plaque Psoriasis | 14 |
| Richard L. Roudebush VA Medical Center, Indianapolis, IN | Prostate Cancer, Actinic Keratosis, Anxiety | 14 |
| Sidney and Lois Eskenazi Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8 | 13 |
| Riley Children's Hospital | Becker Muscular Dystrophy, Bowel Incontinence, CLOVES Syndrome | 12 |
| Franciscan Health | Neoplasm Metastasis, Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms | 11 |
| Franciscan Health Indianapolis | Anatomic Stage IV Breast Cancer AJCC v8, Breast Cancer, Cardiotoxicity | 11 |
| Indiana University Health Methodist Hospital | Diabetic Foot Ulcer (DFU), Acute Ischemic Stroke, Atherosclerotic Cardiovascular Disease (ASCVD) | 10 |
| IU Health University Hospital | Colitis, Ulcerative, Contraception, Crohn Disease | 9 |
| Ascension St. Vincent | Coronary Artery Disease, Aortic Valve Disease, Aortic Valve Stenosis | 8 |
| Indiana University Melvin and Bren Simon Cancer Center | Neoplasm Metastasis, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung | 8 |
| Riley Hospital for Children at Indiana University Health | ADHD - Attention Deficit Disorder With Hyperactivity, Anxiety Disorders, Aortic Coarctation | 8 |
| Midwest Inst For Clin Res | Obesity, Overweight, Diabetes Mellitus, Type 2 | 7 |
| Eskenazi Health | Hypertension, Aerobic Exercise, Alzheimer's Disease (Incl Subtypes) | 6 |
Active & Upcoming Studies in Indianapolis (2026)
Recruiting trials in Indianapolis grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (227 active studies)
- ImmuNe ParameTERs to Predict Immunotherapy REsponse and Toxicity (INTERPRET) · Indiana University
- Therapeutic Induction of Dermal Remodeling in Veterans to Prevent Actinic Neoplasia Caused by Chronic Environmental Exposure to Ultraviolet Radiation · VA Office of Research and Development
Cardiovascular (68 active studies)
- Utilizing Carbon Dioxide for Assessing Coronary Blood Flow in Subjects With Coronary Artery Disease · Indiana University
- LOw DosE Spironolactone, chlorThAlidone oR Combination in CKD Trial · Phase 2 · VA Office of Research and Development
Diabetes & metabolic (53 active studies)
- Effect Of Percutaneous Electrical Nerve Field Stimulation on Symptom Control/Nervous System Activity in Patients w/Diabetes Types 1/2 · Indiana University
- A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event · Phase 2 · Eli Lilly and Company
Neurology & pain (48 active studies)
- Overground Virtual Reality (VR) Gait Rehabilitation for Stroke · Indiana University
- VICA: A Virtual Care Assistant for Dementia Caregivers · Indiana University
Mental health & behavior (23 active studies)
- Improving Mental Healthcare Outcomes for Minoritized Veterans Through a Peer-led, Patient Navigation Program (PARTNER-MH 2.0) · VA Office of Research and Development
- Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder · Phase 1, Phase 2 · Indiana University
Pediatric (14 active studies)
HIV / STI (5 active studies)
- A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIV · Phase 2 · Naga P. Chalasani
- The Effects of Cognitive Behavioral Therapy on Insulin Resistance in People With HIV · Indiana University
Eye & vision (5 active studies)
- An Exploratory Efficacy and Safety Study of DFL24498 Topical Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease · Phase 2 · Dompé Farmaceutici S.p.A
- A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio · Phase 2 · Apellis Pharmaceuticals, Inc.
Vaccines (1 active study)
- Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children · Phase 3 · University of Alabama at Birmingham
Common conditions studied in Indianapolis
- Obesity (17 active studies)
- Heart Failure (14 active studies)
- Prostate Cancer (11 active studies)
- Dementia (10 active studies)
- Multiple Myeloma (10 active studies)
- Coronary Artery Disease (9 active studies)
Leading research sponsors in Indianapolis
- Indiana University
- Eli Lilly and Company
- National Cancer Institute (NCI)
- Children's Oncology Group
- Janssen Research & Development, LLC
Frequently asked questions
How many paid clinical trials are currently recruiting in Indianapolis?
There are approximately 878 recruiting clinical trials in Indianapolis, Indiana listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Indianapolis pay participants?
Most recruiting trials in Indianapolis compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Indianapolis?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Indianapolis?
The most common conditions under active study in Indianapolis include Obesity (17), Heart Failure (14), Prostate Cancer (11), Dementia (10), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Indianapolis?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Indianapolis on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Indianapolis?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Indianapolis?
Recruiting research sites in Indianapolis include Indiana University, Riley Hospital for Children, Indiana University School of Medicine, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Indianapolis right now?
The largest active categories in Indianapolis are Cancer & tumors (227), Cardiovascular (68), Diabetes & metabolic (53). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.