Lung oncology Clinical Trials in Indianapolis, IN
As of September 2026, 30 paid clinical trials are recruiting for Lung oncology in Indianapolis, Indiana. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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30 clinical trials for Lung oncology
·Clear filters·Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
A Study of Alisertib in Patients With Extensive Stage Small Cell Lung Cancer
Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer
MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1
GEMINI-NSCLC: NSCLC Biomarker Study
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan
A Study of LY4175408 in Participants With Advanced Cancer
Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients
A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies
A Study of Tolododekin Alfa (ANK-101) in Combination With an Anti-PD-1/PD-L1 Antibody in Participants With Advanced Non-Small Cell Lung Cancer
A Study of VET3-TGI in Patients With Solid Tumors
Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial
Increasing Equity in Lung Cancer Screening
Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)
Rapid Autopsy Protocol for Patients With Small Cell Lung Cancer
MOnaliZumab in Combination With durvAlumab (MEDI4736) for tRreatmenT of Small Cell Lung Cancer
Repositioning Immunotherapy in VetArans With Lung Cancer
Evaluating a Fasting-mimicking Diet in Combination With Immunotherapy in Patients With Non-small Cell Lung Cancer
Prospective Study on Radiation Induced Cardiotoxicity Assessed By PET-CT for Locally Advanced Non-Small Cell Lung Cancer (NSCLC)
A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer
A Phase 1/2 Clinical Trial to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMBD-501 in Patients With HER3-Expressing Solid Tumors
Top Research Study Locations in Indianapolis
Researchers run research studies in Indianapolis, IN at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Indiana University | Alzheimer Disease, Amyotrophic Lateral Sclerosis, Dementia | 102 |
| Riley Hospital for Children | Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 65 |
| Indiana University School of Medicine | Dementia, Alzheimers Disease, Alzheimers Disease, Familial | 48 |
| Indiana University/Melvin and Bren Simon Cancer Center | Anatomic Stage II Breast Cancer AJCC v8, Acute Myeloid Leukemia, Anatomic Stage IIIA Breast Cancer AJCC v8 | 33 |
| Indiana University Melvin and Bren Simon Comprehensive Cancer Center | Small Cell Lung Cancer, Germ Cell Tumor, Prostate Cancer | 29 |
| Saint Catherine Hospital | Anatomic Stage II Breast Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Advanced Esophageal Adenocarcinoma | 22 |
| Indiana University Health | Myasthenia Gravis, Acetabulum Fractures, Acute Ischemic Stroke | 21 |
| Indiana University Health University Hospital | Eosinophilic Esophagitis, Gastroparesis, Obesity or Overweight | 20 |
| Community Health Network | Colorectal Cancer, Pancreatic Ductal Adenocarcinoma, Head and Neck Squamous Cell Carcinoma | 19 |
| Indiana University Hospital | Gastroparesis, Abnormal Uterine Bleeding, Achalasia | 16 |
| Ascension Saint Vincent Indianapolis Hospital | Acute Myeloid Leukemia, Malignant Solid Neoplasm, Mixed Phenotype Acute Leukemia | 14 |
| Dawes Fretzin Clinical Research Group, LLC | Atopic Dermatitis, Alopecia Areata, Eczema | 14 |
| IU Health Methodist Hospital | Coronary Artery Disease, Atrial Fibrillation, Breast Implant; Complications | 14 |
| Richard L. Roudebush VA Medical Center, Indianapolis, IN | Prostate Cancer, Actinic Keratosis, Anxiety | 14 |
| Sidney and Lois Eskenazi Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8 | 13 |
| Franciscan Health Indianapolis | Anatomic Stage IV Breast Cancer AJCC v8, Breast Cancer, Cardiotoxicity | 12 |
| Riley Children's Hospital | Becker Muscular Dystrophy, Bowel Incontinence, CLOVES Syndrome | 12 |
| Franciscan Health | Neoplasm Metastasis, Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms | 11 |
| Indiana University Health Methodist Hospital | Diabetic Foot Ulcer (DFU), Acute Ischemic Stroke, Atherosclerotic Cardiovascular Disease (ASCVD) | 11 |
| IU Health University Hospital | Colitis, Ulcerative, Contraception, Crohn Disease | 10 |
| Ascension St. Vincent | Coronary Artery Disease, Aortic Valve Disease, Aortic Valve Stenosis | 9 |
| Indiana University Melvin and Bren Simon Cancer Center | Neoplasm Metastasis, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung | 7 |
| Riley Hospital for Children at Indiana University Health | ADHD - Attention Deficit Disorder With Hyperactivity, Anxiety Disorders, Aortic Coarctation | 7 |
| Eskenazi Health | Hypertension, Aerobic Exercise, Alzheimer's Disease (Incl Subtypes) | 6 |
| IU Health Neuroscience Center | Epilepsy, Epilepsy (Treatment Refractory), Acute Pain | 6 |
Active & Upcoming Studies in Indianapolis (2026)
Recruiting trials in Indianapolis grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (233 active studies)
- ImmuNe ParameTERs to Predict Immunotherapy REsponse and Toxicity (INTERPRET) · Indiana University
- Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial · Phase 3 · National Cancer Institute (NCI)
Cardiovascular (70 active studies)
- Utilizing Carbon Dioxide for Assessing Coronary Blood Flow in Subjects With Coronary Artery Disease · Indiana University
- LOw DosE Spironolactone, chlorThAlidone oR Combination in CKD Trial · Phase 2 · VA Office of Research and Development
Diabetes & metabolic (52 active studies)
- Effect Of Percutaneous Electrical Nerve Field Stimulation on Symptom Control/Nervous System Activity in Patients w/Diabetes Types 1/2 · Indiana University
- Supplementation of Gut-brain Axis (GLP-1)-Activating Carbohydrates for Increasing Satiety in Adolescents With Obesity · Phase 2 · Indiana University
Neurology & pain (52 active studies)
Mental health & behavior (22 active studies)
- Improving Mental Healthcare Outcomes for Minoritized Veterans Through a Peer-led, Patient Navigation Program (PARTNER-MH 2.0) · VA Office of Research and Development
- Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder · Phase 1, Phase 2 · Indiana University
Pediatric (14 active studies)
HIV / STI (6 active studies)
- Study of GS-0415 and How It Works in People With HIV · Phase 1 · Gilead Sciences
- A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIV · Phase 2 · Naga P. Chalasani
Eye & vision (4 active studies)
- An Exploratory Efficacy and Safety Study of DFL24498 Topical Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease · Phase 2 · Dompé Farmaceutici S.p.A
- A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio · Phase 2 · Apellis Pharmaceuticals, Inc.
Vaccines (1 active study)
- Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children · Phase 3 · University of Alabama at Birmingham
Common conditions studied in Indianapolis
- Obesity (16 active studies)
- Heart Failure (15 active studies)
- Prostate Cancer (11 active studies)
- Dementia (10 active studies)
- Breast Cancer (9 active studies)
- Coronary Artery Disease (9 active studies)
Leading research sponsors in Indianapolis
- Indiana University
- Eli Lilly and Company
- National Cancer Institute (NCI)
- Children's Oncology Group
- VA Office of Research and Development
Frequently asked questions
How many paid clinical trials are currently recruiting in Indianapolis?
There are approximately 881 recruiting clinical trials in Indianapolis, Indiana listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Indianapolis pay participants?
Most recruiting trials in Indianapolis compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Indianapolis?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Indianapolis?
The most common conditions under active study in Indianapolis include Obesity (16), Heart Failure (15), Prostate Cancer (11), Dementia (10), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Indianapolis?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Indianapolis on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Indianapolis?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Indianapolis?
Recruiting research sites in Indianapolis include Indiana University, Riley Hospital for Children, Indiana University School of Medicine, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Indianapolis right now?
The largest active categories in Indianapolis are Cancer & tumors (233), Cardiovascular (70), Diabetes & metabolic (52). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.